Asymmetric Synthesis of Allylamines by Regio- and Diastereoselective 1,2-Addition of Organolithium Reagents to Conjugated Sulfinimines [0.03%]
共轭亚磺基亚胺与有机锂试剂的区域和非对映选择性1,2-加成反应用于 allylamines 的不对称合成
Anaïs Loison,Nicolò Rossi,Gwilherm Evano
Anaïs Loison
A practical, robust, and straightforward access to optically enriched allylamines by a regio- and diastereoselective 1,2-addition of organolithium reagents to Davis-Ellman-type chiral conjugated sulfinimines is reported. The procedure is op...
Enantioselective Synthesis of (8 S,9 S,16 S)-Beraprost through a Yb(OTf)3-Catalyzed Diastereoselective Diels-Alder/Retro-Diels-Alder and Pd(TFA)2-Catalyzed Aromatization Process [0.03%]
通过Yb(OTf)3催化的Diels-Alder/反向Diels-Alder和Pd(TFA)2催化的芳构化过程进行（8S，9S，16S）-贝前列素的对映选择性合成
Nai-Xuan Liu,Xin Li,Jian-Ting Sun et al.
Nai-Xuan Liu et al.
An enantioselective synthetic route to the most active stereoisomer, (8S,9S,16S)-beraprost, through a mild and scalable Yb(OTf)3-catalyzed diastereoselective inverse-electron-demand Diels-Alder/retro-Diels-Alder and Pd(TFA)2-catalyzed aroma...
Decarbonylation Enables Chemodivergent Access to Guaiazulene-3-Oxalic and -Carboxylic Acid Derivatives [0.03%]
脱碳 monylation 实现 Guaiazulene-3-oxalic 和-carboxylic 酸衍生物的化学发散合成
Emma Audi,Carly M Zack,Esther M Ntankwa et al.
Emma Audi et al.
Guaiazulene derivatives are of interest due to the low cost of guaiazulene compared to azulene while still retaining many of the same unique electronic properties. Syntheses of guaiazulene-3-carboxylic acid and azulene-1-carboxylic acid der...
Highly Active cis-Diphosphinoalkenyl-Nickel Catalysts for Suzuki-Miyaura Cross-Coupling Reaction of Aryl Chlorides and Aryl Boronic Acids [0.03%]
高活性cis-双亚磷酸酯烯基镍催化剂用于芳基氯和芳基硼酸的Suzuki-Miyaura交叉偶联反应
Xiaoli Li,Mengyang Wang,Chaoyin Zhu et al.
Xiaoli Li et al.
A new class of cis-diphosphinoalkenyl-nickel complexes were designed/synthesized as efficient precatalysts for Suzuki-Miyaura coupling of less reactive aryl chlorides with arylboronic acids. Ligand's rigid five-membered ring and balanced st...
Photo-triggered Formation of an Amidinyl Radical from O-Nitroveratril Amidoxime and Its Intramolecular Cyclization in Aqueous Media [0.03%]
光激发O-硝基桂皮酰胲肟氨基
Hidenori Okamura,Yui Kaneyama,Kenshin Norizuki et al.
Hidenori Okamura et al.
Photochemical reactions compatible with physiological conditions are powerful tools for chemical biology and medicinal chemistry. Herein, we report that 3,4-dimethoxy-o-nitrobenzyl (o-nitroveratril) amidoxime ethers generate amidinyl radica...
Synthesis, Structure, and Reactivity of Hypervalent Iodine Reagents Stabilized by Internal Out-of-Plane Halogen Bonding: ortho- Bromo and ortho- Chloro-Substituted [Hydroxy(tosyloxy)iodo]arenes and Iodonium Ylides [0.03%]
由内部分子内平面外卤素键稳定的第一过渡态效应卤素试剂的合成、结构和反应性：邻溴和邻氯代[羟基(托索基)碘苯]和重氮onium盐离子
Niloofar Zarrabi,Grayson Hughes,Brianna Herrmann et al.
Niloofar Zarrabi et al.
The preparation and reactivity of a series of ortho-halogen-substituted (diacetoxyiodo)arenes, [hydroxy(tosyloxy)iodo]arenes, and aryliodonium ylides are reported. X-ray analysis of 1-[hydroxy(tosyloxy)iodo]-2-bromobenzene confirms the pres...
Ze-Yu Su,Yi-Rui Zhang,Jun-Hui Luo et al.
Ze-Yu Su et al.
α-Amino carbonyl compounds are valuable building blocks for diverse pharmaceuticals and natural products. However, current synthetic methods often rely on specialized nitrogen reagents, stoichiometric oxidants, or metal catalysts, highligh...
Synthesis of Polyhydroxylated Dihydro-Oxazines, Their Reactivity Studies, and Applications in the Construction of 1,2-Oxazinane Iminosugar Library with Bioactivities [0.03%]
聚羟基二氢氧化氮的合成、反应性研究及其在构建具有生物活性的1,2-氧杂环己烷氨基糖库中的应用
Chen-Hao Xu,Kosuke Yoshimura,Atsumi Taguchi et al.
Chen-Hao Xu et al.
Four polyhydroxylated dihydro-oxazines have been synthesized as competitive products of well-known nitrones from corresponding carbohydrates through efficient and practical procedures involving a five-to-seven-steps sequence in moderate ove...
Yeliang Xue,Shaozhong Wang
Yeliang Xue
We report an efficient, metal-free electrochemical synthesis of sulfonylated aminoquinones via electrooxidative denitrogenation of sulfonyl hydrazides. Anodic denitrogenation generates sulfonyl radicals that undergo chemo- and regioselectiv...
Bowl-Shaped π-Extended Phosphangulenes: Synthesis and Structure-Dependent Modulation of Circularly Polarized Luminescence [0.03%]
碗型π共轭磷杂角硫烯的合成及其圆偏振发光的手性调节研究
Huijie Li,Heyang Li,Yang Cheng et al.
Huijie Li et al.
Bowl-shaped conjugated materials have emerged as a compelling class of materials due to their unique structural topology and exceptional chiral optoelectronic characteristics. Among these, phosphorus-embedded curved polycyclic aromatic phos...