Membrane Protein Design: From Reprogramming Functions to AI-Guided De Novo Design Approaches [0.03%]
膜蛋白设计:从功能重构到人工智能引导的从头设计方法
Robert E Jefferson,Patrick Barth
Robert E Jefferson
Computational membrane protein design has rapidly evolved from early physics-based modeling into a mature discipline powered by high-throughput experimental screening and cutting-edge AI technologies. The convergence of these approaches is ...
Nanoscale CO2 Interfacial Reactions and Their Impacts on Sustainable Carbon Management [0.03%]
纳米尺度二氧化碳界面反应及其对可持续碳管理的影响
Young-Shin Jun,Minkyoung Jung,Ying Wang et al.
Young-Shin Jun et al.
The global rise in atmospheric CO2 concentration and its societal impact urges the development of sustainable carbon management via carbon capture, utilization, and storage (CCUS) strategies. Although CCUS addresses a challenge of global sc...
Topological Data Analysis in Materials Science: Principles, Machine Learning Integration, and Application Landscapes [0.03%]
材料科学中的拓扑数据分析:原理、机器学习集成及应用前景
Shisheng Zheng,Bingxu Wang,Mengmeng Zhang et al.
Shisheng Zheng et al.
The data-driven paradigms are reshaping materials science, placing unprecedented emphasis on the digital characterization and representation of the material data. Topological Data Analysis (TDA) methods offer a promising and innovative appr...
Photocatalytic Reduction-Oxidation System for Synergistic Utilization of Photogenerated Electrons and Holes [0.03%]
协同利用光生电子和空穴的光电催化红ox体系
Boxin Liu,Xin Tan,Tao Yu et al.
Boxin Liu et al.
The efficient and simultaneous utilization of photogenerated electrons and holes in photocatalytic reduction-oxidation (redox) reactions is currently an important trend in photocatalysis. This review systematically describes photocatalytic ...
Robert D Crapnell,Elena Bernalte,Craig E Banks
Robert D Crapnell
Fused filament fabrication (FFF) has rapidly evolved from a prototyping tool into a powerful platform for electrochemical device innovation. Its accessibility, design freedom, and compatibility with diverse polymers have enabled breakthroug...
Wired and Wireless Photosynthetic Biohybrids: Design, Materials, and Mechanisms [0.03%]
有线和无线光合作用生物混合体:设计、材料及机制
Lihini Jayasinghe,Wonseok Lee,Andrew Liu et al.
Lihini Jayasinghe et al.
Photosynthetic biohybrid systems (PBSs) integrate semiconductor light harvesters with microbial metabolism to enable solar-driven chemical synthesis, yet the chemical principles governing their performance remain dispersed across two distin...
Qiang Zhang,Wenjun Liao,Ling Lin et al.
Qiang Zhang et al.
Single-cell total-analysis aims to bridge the gap between cellular molecular makeup and functional phenotype, deciphering how genomic, transcriptomic, proteomic, and metabolic networks orchestrate phenotypic outcomes. Despite rapid omics ad...
Mikus Puriņš,Cecile Elgindy,Mark D Levin
Mikus Puriņš
Recent advances have made possible the replacement of individual atoms within a molecular skeleton while preserving the integrity of the surrounding framework. These skeletal editing reactions are emerging as powerful tools for molecular op...
Relay Catalysis in Selective Transformations of C1 into C2+ Molecules [0.03%]
C1分子选择性转化为C2+分子的接力催化研究进展
Yubing Li,Suhan Liu,Yu Xie et al.
Yubing Li et al.
C1 molecules (e.g., CO, CO2, CH4, and CH3OH) are pivotal platforms for synthesizing fuels and chemicals from nonpetroleum resources. However, the selective activation of C-O and C-H bonds, precise control of C-C formation, and preservation ...
Membrane Protein Insertion in Cells: Principles, Pathways, and Quality Control [0.03%]
细胞膜蛋白插入:原理、途径及质量控制
Hadas Peled-Zehavi,Reut Yemini,Nir Fluman
Hadas Peled-Zehavi
Integral membrane proteins comprise at least a quarter of every proteome. To fold and function properly, these proteins must insert into the correct membrane with the proper topology and orientation. Although their transmembrane helices are...