Selection of Nucleotide-Encoded Mass Libraries of Macrocyclic Peptides for Inaccessible Drug Targets [0.03%]
用于难以成药靶点的核苷酸编码大环肽质谱库的选择
Kilian Colas,Daniel Bindl,Hiroaki Suga
Kilian Colas
Technological advances and breakthrough developments in the pharmaceutical field are knocking at the door of the "undruggable" fortress with increasing insistence. Notably, the 21st century has seen the emergence of macrocyclic compounds, a...
Matthew C Lamb,Keri A Steiniger,Leslie K Trigoura et al.
Matthew C Lamb et al.
Electrocatalysis and photocatalysis have been the focus of extensive research efforts in organic synthesis in recent decades, and these powerful strategies have provided a wealth of new methods to construct complex molecules. Despite these ...
Wenlong Ding,Jiayu Gu,Wenyuan Xu et al.
Wenlong Ding et al.
Protein lipidation dramatically affects protein structure, localization, and trafficking via remodeling protein-membrane and protein-protein interactions through hydrophobic lipid moieties. Understanding the biosynthesis of lipidated protei...
Jonathan D Schultz,Jonathon L Yuly,Eric A Arsenault et al.
Jonathan D Schultz et al.
Coherence refers to correlations in waves. Because matter has a wave-particle nature, it is unsurprising that coherence has deep connections with the most contemporary issues in chemistry research (e.g., energy harvesting, femtosecond spect...
Merocyanines: Electronic Structure and Spectroscopy in Solutions, Solid State, and Gas Phase [0.03%]
墨氰化合物：溶液、固态和气相中的电子结构与光谱学
Andrii V Kulinich,Alexander A Ishchenko
Andrii V Kulinich
Merocyanines, owing to their readily tunable electronic structure, are arguably the most versatile functional dyes, with ample opportunities for tailored design via variations of both the donor/acceptor (D/A) end groups and π-conjugated po...
Correction to "P-Stereogenic Phosphorus Ligands in Asymmetric Catalysis" [0.03%]
“不对称催化中P-手性磷配体的研究”的更正
Tsuneo Imamoto
Tsuneo Imamoto
Published Erratum
Chemical reviews. 2024 Nov 13;124(21):12382-12389. DOI:10.1021/acs.chemrev.4c00658 2024
Reaching New Heights in Genetic Code Manipulation with High Throughput Screening [0.03%]
高通量筛选在基因密码操纵中达到新的高度
Briana R Lino,Sean J Williams,Michelle E Castor et al.
Briana R Lino et al.
The chemical and physical properties of proteins are limited by the 20 canonical amino acids. Genetic code manipulation allows for the incorporation of noncanonical amino acids (ncAAs) that enhance or alter protein functionality. This revie...
Shukun Yin,Dickson R Yao,Yu Song et al.
Shukun Yin et al.
Soft robotics presents innovative solutions across different scales. The flexibility and mechanical characteristics of soft robots make them particularly appealing for wearable and implantable applications. The scale and level of invasivene...
Correction to Recyclable and (Bio)degradable Polyesters in a Circular Plastics Economy [0.03%]
可循环和（生物）可降解聚酯在循环经济中的应用的更正文章
Changxia Shi,Ethan C Quinn,Wilfred T Diment et al.
Changxia Shi et al.
Published Erratum
Chemical reviews. 2024 Oct 23;124(20):11637. DOI:10.1021/acs.chemrev.4c00712 2024
Aryne Chemistry: Generation Methods and Reactions Incorporating Multiple Arynes [0.03%]
芳基炔化学：生成方法及多分子芳基炔反应
Nayoung Kim,Myungsoo Choi,Sung-Eun Suh et al.
Nayoung Kim et al.
Arynes hold significance for the efficient fusion of (hetero) arenes with diverse substrates, advancing the construction of complex molecular frameworks. Employing multiple equivalents of arynes is particularly effective in the rapid format...