Sigitas Mikutis,Gonçalo J L Bernardes
Sigitas Mikutis
The vast majority of the human genome codes for RNA, but RNA-targeting therapeutics account for a small fraction of approved drugs. As such, there is great incentive to improve old and develop new approaches to RNA targeting. For many RNA t...
Computational Tools for Hydrogen-Deuterium Exchange Mass Spectrometry Data Analysis [0.03%]
氢氘交换质谱数据的计算工具
Michele Stofella,Antonio Grimaldi,Jochem H Smit et al.
Michele Stofella et al.
Hydrogen-deuterium exchange (HDX) has become a pivotal method for investigating the structural and dynamic properties of proteins. The versatility and sensitivity of mass spectrometry (MS) made the technique the ideal companion for HDX, and...
Understanding and Tuning the Effects of H2O on Catalytic CO and CO2 Hydrogenation [0.03%]
水对催化CO和CO2氢化作用的影响及调控机制研究
Mingrui Wang,Guanghui Zhang,Hao Wang et al.
Mingrui Wang et al.
Catalytic COx (CO and CO2) hydrogenation to valued chemicals is one of the promising approaches to address challenges in energy, environment, and climate change. H2O is an inevitable side product in these reactions, where its existence and ...
Electrochemical and Non-Electrochemical Pathways in the Electrocatalytic Oxidation of Monosaccharides and Related Sugar Alcohols into Valuable Products [0.03%]
单糖及类似糖醇电催化氧化生成高附加值产品的电化学和非电化学路径研究
Matthijs P J M van der Ham,Jordi Creus,Johannes H Bitter et al.
Matthijs P J M van der Ham et al.
In this contribution, we review the electrochemical upgrading of saccharides (e.g., glucose) and sugar alcohols (e.g., glycerol) on metal and metal-oxide electrodes by drawing conclusions on common trends and differences between these two i...
Additions and Corrections to Cleavage of Si-H, B-H and C-H Bonds by Metal-Ligand Cooperation [0.03%]
关于金属配体合作断裂硅氢、硼氢和碳氢键的补遗和更正
Takuya Higashi,Shuhei Kusumoto,Kyoko Nozaki
Takuya Higashi
Published Erratum
Chemical reviews. 2024 Nov 13;124(21):12381. DOI:10.1021/acs.chemrev.4c00563 2024
Alan Costello,Alexander A Peterson,Pei-Hsin Chen et al.
Alan Costello et al.
The genetic code is the foundation for all life. With few exceptions, the translation of nucleic acid messages into proteins follows conserved rules, which are defined by codons that specify each of the 20 proteinogenic amino acids. For dec...
Evolution of Copolymers of Epoxides and CO2: Catalysts, Monomers, Architectures, and Applications [0.03%]
环氧乙烷和二氧化碳共聚物的发展：催化剂、单体、结构与应用
Guan-Wen Yang,Rui Xie,Yao-Yao Zhang et al.
Guan-Wen Yang et al.
The copolymerization of CO2 and epoxides presents a transformative approach to converting greenhouse gases into aliphatic polycarbonates (CO2-PCs), thereby reducing the polymer industry's dependence on fossil resources. Over the past 50 yea...
Defect Chemistry of Titanium Dioxide (Rutile). Progress Toward Sustainable Energy [0.03%]
二氧化钛（金红石）的缺陷化学。迈向可持续能源的步伐
Tadeusz Bak,S A Sherif,David StClair Black et al.
Tadeusz Bak et al.
This work, which overviews defect chemistry of TiO2 (rutile), is focused on atomic-size structural defects that are thermodynamically reversible. Here it is shown that thermodynamics can be used in defect engineering of TiO2-based energy ma...
Selection of Nucleotide-Encoded Mass Libraries of Macrocyclic Peptides for Inaccessible Drug Targets [0.03%]
用于难以成药靶点的核苷酸编码大环肽质谱库的选择
Kilian Colas,Daniel Bindl,Hiroaki Suga
Kilian Colas
Technological advances and breakthrough developments in the pharmaceutical field are knocking at the door of the "undruggable" fortress with increasing insistence. Notably, the 21st century has seen the emergence of macrocyclic compounds, a...
Matthew C Lamb,Keri A Steiniger,Leslie K Trigoura et al.
Matthew C Lamb et al.
Electrocatalysis and photocatalysis have been the focus of extensive research efforts in organic synthesis in recent decades, and these powerful strategies have provided a wealth of new methods to construct complex molecules. Despite these ...