Deep Learning-Aided SERS Detection of Microplastics in Water Samples with a Hierarchically Porous Gold Sponge Substrate [0.03%]
一种用于水样中微塑料深拉曼检测的深度学习辅助分层多孔金海绵基底
Zhenli Sun,Yiyan Zhang,Jingjing Du et al.
Zhenli Sun et al.
The pervasive occurrence of microplastics (MPs) in aquatic environments presents growing challenges for environmental monitoring. Conventional MP detection methods often require extensive pretreatment and struggle to differentiate mixed pol...
A Tailored Monoclonal Antibody for Visual Detection of an Emerging Insecticide Chlorfenapyr: Rational Hapten Design and Molecular Insights [0.03%]
一种用于检测新型杀虫剂氯苯醚的单克隆抗体的合理半抗原设计及分子见解：定制化Tailored Monoclonal Antibody可视化检测新出现的杀虫剂Chlorfenapyr：合理半抗原设计和分子见解
Shuai Kou,Liqiang Liu,Aihong Wu et al.
Shuai Kou et al.
Chlorfenapyr (CFP), a novel pyrrole-class insecticide, in the environment and agricultural products pose a threat to human health and ecological balance. This study designed five CFP-hapten conjugates. By computer simulations predict highly...
Quantitative Analysis of Multiple Serum Tumor Biomarkers by an Interpretable Stacked Ensemble Model [0.03%]
基于解释性的堆叠集成模型的多种血液肿瘤生物标志物的定量分析
Boyu Wu,Jiawei Chen,Yanheng Huang et al.
Boyu Wu et al.
Surface-enhanced Raman spectroscopy (SERS) offers exceptional sensitivity and specificity for biomolecular detection, particularly in analyzing serum tumor biomarkers. However, its application is hindered by spectral complexity and matrix i...
Viral Capsid Protein Architecture Informed Selection of ssDNA Aptamers for Specific Detection of FMDV [0.03%]
基于病毒壳蛋白结构的牛传染性鼻气管炎病毒DNA aptamer筛选及鉴定
Jin-Pyo Lee,Hee-Young Cho,Woo-Ri Shin et al.
Jin-Pyo Lee et al.
Foot-and-mouth disease virus (FMDV) is a highly contagious pathogen that poses a serious threat to the global livestock industry, highlighting the need for stable and serotype-specific diagnostic tools. In this study, single-stranded DNA (s...
In Situ Visualization of Electrocatalytic Interfacial pH Changes via the Use of Phosphates as the Probe [0.03%]
利用磷酸盐作为探针原位可视化电催化界面pH变化
Changchun Jiao,Xiang Li,Bin Zhang et al.
Changchun Jiao et al.
The interfacial pH distribution throughout the electrode has a considerable influence on the electrocatalytic performance. However, a local pH mapping method that can be applied to various electrocatalytic electrodes over a full pH range is...
R Krishna,G Millard,R Bradshaw et al.
R Krishna et al.
Since its inception in 2004, Desorption Electrospray Ionization Mass Spectrometry (DESI MS) has seen a significant increase in its application to the pharmaceutical and clinical setting, supported by a steady improvement of the sensitivity,...
3D Glioblastoma Molecular Responses to Carbon Dot-Delivered Riluzole Probed by Synchrotron FTIR [0.03%]
同步傅里叶变换红外探针碳点递送利鲁唑的胶质母细胞多分子反应
Tanja Dučić,Manuel Algarra,David Pérez Guaita et al.
Tanja Dučić et al.
Engineered carbon-based nanocarriers provide a versatile platform for probing drug delivery-induced molecular responses in complex cellular models. Here, we report 2-acrylamido-2-methylpropanesulfonic acid (AMPS)-derived carbon dots (CDs) a...
Broad Cross-Reactivity of a Microcystin ELISA Confirmed Using 19 Quantitative Reference Materials [0.03%]
利用19种定量参考物质验证微囊藻毒素酶联免疫吸附测定的广泛交叉反应性
Ingunn A Samdal,Luisa Florizoone,Kjersti L E Løvberg et al.
Ingunn A Samdal et al.
Microcystins (MCs) are toxins produced by cyanobacteria and are found worldwide. Exposure may be acute or chronic through contaminated drinking water, food (such as vegetables), dietary supplements, and recreational activities. Acute exposu...
Cryo-HIM-SIMS on the npSCOPE: Correlative Topographic, Transmitted and SIMS Imaging at Cryogenic Temperatures [0.03%]
冷冻HIM-SIMS在npSCOPE上的相关形貌、透射和SIMS成像研究
Tatjana Taubitz,Olivier De Castro,Dustin Andersen et al.
Tatjana Taubitz et al.
Multimodal helium ion microscopy (HIM) and secondary ion mass spectrometry (SIMS) provide in situ spatial imaging and chemical analysis at nanoscale resolution. Operation at cryogenic temperatures is needed to overcome artifacts related to ...
CRISPR/dCas9-Assisted On-Bead Multiplex Detection (BeadPlex2) for Genetically Modified Crops [0.03%]
基于CRISPR/dCas9的磁珠法多重检测技术(BeadPlex2)及其在转基因鉴定中的应用
Huimin Wang,Feiwu Li,Yuxuan He et al.
Huimin Wang et al.
This study leverages the precise recognition ability of CRISPR/dCas9 and the Raman coding feature of the gap-enhanced Raman tag-encoded magnetic beads (MagGERTs) to create a unique on-bead nucleic acid detection platform (BeadPlex2) for acc...