Multifunctional Composite Coating-Enhanced Flexible Microelectrodes for Chronic, High-Fidelity Neural Signal Recording [0.03%]
多功能复合涂层增强型柔性微电极用于慢性高保真神经信号记录
Ji Pang,Yuyang Sun,Tingting Cheng et al.
Ji Pang et al.
Implantable flexible neuroelectrodes are critical for brain-computer interface (BCI) applications. However, conventional flexible electrodes often face challenges such as increased electrochemical impedance upon miniaturization, mechanical ...
Utilizing Engineered Monobodies for the Electrochemical Quantification of Lysozyme [0.03%]
利用工程化单抗体进行溶菌酶的电化学定量分析
Sunanda Dey,Andrew Naser,Daniel R Woldring et al.
Sunanda Dey et al.
Monobody binding proteins are derived from the Fn3 domain of human fibronectin. These robust proteins can be engineered to bind to a wide range of small molecule-, nucleotide-, or large biomolecule-based analytes with high specificity and s...
In-Line NMR Diagnostics of Hydroformylation Provided by the Segmented-Flow Microfluidic Regime [0.03%]
连续流动微反应器中实施的氢甲酰化反应的在线核磁监测研究
Mahmoud E A Eid,Maria V Nenasheva,Aleksei N Bulgakov et al.
Mahmoud E A Eid et al.
Hydroformylation is an industrial method for the conversion of olefins to aldehydes, which are further transformed to other valuable products, including primary alcohols. In industry, it is catalyzed by Rh and Co complexes, mostly under hom...
A Novel Ficoll400-Based Signal Amplification Platform for High-Sensitive Cardiac Troponin I Immunoassay [0.03%]
一种基于新型Ficoll400的心肌肌钙蛋白I高灵敏免疫检测信号放大平台
Chaolin Guo,Meng Liu,Shuaipeng Li et al.
Chaolin Guo et al.
This study reports the development of a novel signal amplification carrier based on the soluble macromolecular polysaccharide Ficoll400 to enhance the sensitivity of chemiluminescent immunoassays (CLIA), with a particular focus on detecting...
Proximity-Inducible CRISPR/Cas12a Activity by Scaffold RNA Assembly for Sensing Applications [0.03%]
通过支架RNA组装诱导CRISPR/Cas12a作用实现传感检测功能
Yin Gang Nie,Hong-Shuai Zhang,Mei Su et al.
Yin Gang Nie et al.
The programmability and flexibility of the RNA-directed CRISPR/Cas12a system underpin its utility as a potent tool for diagnostic applications. However, existing engineered crRNA strategies are still limited by a narrow target range, inadeq...
Tasneem Omda Edrees Isaa,Ala&#x;a Mhmoued Abdllh Alboull,Hao Jiang et al.
Tasneem Omda Edrees Isaa et al.
This study introduces isostatic graphite (ISG) as a novel electrode material for electroanalysis for the first time. Characterized by its homogeneous and isotropic structure with ultrahigh density and low cost, ISG was employed for the simu...
Visualizing Viscosity Changes in Tumor and Rheumatoid Arthritis with a Dual-Targeted NIR Fluorescent Probe [0.03%]
用于肿瘤和类风湿性关节炎的粘度变化的近红外荧光双靶向探针可视化
Peng Lei,Pengjia Wei,Chuan Dong et al.
Peng Lei et al.
Targeting mitochondria and nucleus fluorescent probes have emerged as powerful tools for monitoring cellular processes, such as apoptosis and ferroptosis. Nevertheless, only a few near-infrared (NIR) fluorescent probes have been developed f...
Source Fingerprinting of PFOA via Full- and Intramolecular Stable Isotope Ratios of Carbon Using Orbitrap-IRMS [0.03%]
基于轨道离子阱与同位素比质谱联用的全分子和内分子稳定碳同位素比率来源指纹法定量PFOA
Holden M Nelson,Zhiliang Xu,Hui Li et al.
Holden M Nelson et al.
Remediation approaches for reducing environmental loading of perfluoroalkyl and polyfluoroalkyl substances (PFAS) require the ability to track PFAS origin sources. One common source attribution method for environmental contaminants is stabl...
Real-Time Monitoring of Drug Release in Whole Blood Based on Optical Interferometry [0.03%]
基于光学干涉的全血中药物释放实时监测研究
Nian Ding,Na Ni,Xinyu Yang et al.
Nian Ding et al.
An efficient strategy was established to achieve real-time monitoring of doxorubicin hydrochloride release based on a functionalized silica colloidal crystal (SCC) interferometric layer and the ordered porous layer interferometry system. An...
Three Conformations of Polyglutamic Acid Monitored by Vibrational Optical Activity [0.03%]
聚谷氨酸三种构象的振动光学活性监测
Andrii S Kurochka,Jana Hudecová,Josef Kapitán et al.
Andrii S Kurochka et al.
Polyglutamic acid (PGA) is an excellent model system to study peptide and protein folding. Its conformation in solution can be conveniently studied by vibrational optical activity. To better understand the behavior of the molecule in differ...