Mobile Protein Microboxes on Optical Fibers for Spatial Micromanipulation of Bacterial Microcolonies [0.03%]
Basu R Aryal,C Hyun Ryu,Jason B Shear et al.
Basu R Aryal et al.
Precise spatial control over cell populations offers new opportunities to investigate how physical proximity influences intercellular interactions. While we previously utilized the microfabrication of protein hydrogels for surface patternin...
Dual-Phase High-Emission Fan-Shaped Donor-Acceptor Molecules for Multiple-Scenario VOC Sensing [0.03%]
Wenpeng Wei,Xiaozheng Zhao,Mengjia Li et al.
Wenpeng Wei et al.
Donor-acceptor fluorophores often suffer from low luminescent efficiency in either solution or solid states due to nonradiative decay and aggregation-caused quenching. This study reports the rational design of two novel fan-shaped fluoropho...
Machine Learning-Enhanced Raman Spectroscopy for Microfiber Detection: From Model Development to Coastal Investigation [0.03%]
Ruoqun Yan,Jiawei Li,Yuanfang Wan et al.
Ruoqun Yan et al.
Microfibers are recognized as the most prevalent form of microplastics, with a widespread distribution across various ecosystems. The distinctive morphology of microfibers provides additional insights into their detection. In contrast to mo...
Wan Zhong,Mengxi Guo,Shihao Sun et al.
Wan Zhong et al.
Electrochemiluminescence (ECL) intensity is simultaneously influenced by both the electron-transfer and mass transport processes. However, the current concerns with ECL amplification focus on either electron transfer or ion transport. In th...
Mikhail L Felshtyn,Olga M Gorbenko,Stanislav Yu Lukashenko et al.
Mikhail L Felshtyn et al.
The stiffness modulus and stability loss force were experimentally and theoretically studied for conical glass nanopipettes of various shapes with an outer aperture diameter of ∼100 nm and a wall thickness at the tip of ∼30 nm. The experi...
NIR-Responsive AuAgPt Plasmonic Nanozyme: Colorimetric/Photothermal Dual-Signal Sensing Array for Discriminating and Detecting Sulfur-Containing Compounds [0.03%]
Qian Wu,Fang Sun,Haixia Kong et al.
Qian Wu et al.
Accurate discrimination and quantification of sulfur-containing compounds (SCCs) are essential for food safety. Herein, a near-infrared (NIR)-responsive AuAgPt ternary metallic plasmonic nanozyme is engineered, exploiting its broad NIR-I/II...
Optimized Low-Field Differential Ion Mobility Separations with High-Resolution Mass Spectrometry for Top-Down Proteomics [0.03%]
Hayden A Thurman,Pratima Pathak,Egor Gusachenko et al.
Hayden A Thurman et al.
Ion mobility spectrometry (IMS) with mass spectrometry (MS) is a versatile approach to simplify mixtures, distinguish isomers, and elucidate molecular geometries. While linear IMS relies on the mobility K at moderate normalized electric fie...
DNA Logic Gate-Integrated Peptide Nucleic Acid-Optical Fiber Sensor for Ultrasensitive Breast Cancer Exosome Profiling [0.03%]
Siqi Zhao,Xueyong Tian,Chushi Chen et al.
Siqi Zhao et al.
Tumor-derived exosomes (TDEs) have emerged as promising biomarkers for cancer liquid biopsy. However, their phenotypic heterogeneity and trace-level concentrations pose considerable analytical challenges, hampering the advancement of highly...
TOI-IGRA: A Fingertip Blood Biosensing Technology for Decentralized Quantification of Pathogen-Specific T-Cell Responses [0.03%]
Yuzhong Xu,Binmao Zhang,Zhen Huang et al.
Yuzhong Xu et al.
T-cell immune responses are key components of the adaptive immune system. The Interferon-γ Release Assay (IGRA), a standardized method for evaluating T-cell function, is widely used for tuberculosis (TB) diagnosis. However, conventional IG...
Challenges and Good Practices in Preprocessing and Normalization of Untargeted DNA Adductomics Data in Exposomics Research [0.03%]
exposome研究中非目标DNA加合物组学数据预处理与标准化的挑战及良好实践
Pablo Vangeenderhuysen,Matthijs Vynck,Liesa Engelen et al.
Pablo Vangeenderhuysen et al.
DNA adductomics is the study of the whole of DNA adducts in a biological sample and is a valuable asset to exposomics research. To date, a clear view on how to analyze larger sample series is lacking in DNA adductomics, and the preprocessin...