DNA Hybridization-Accelerated Programmable Immuno-Aggregation of Microbeads Enabling Mix-and-Read Flow Cytometric Protein Analysis [0.03%]
用于蛋白质分析的混合并读取型流式细胞仪免疫聚集体的DNA杂交加速程序化微球免疫聚集技术
Junyue Sun,Xinrui Fei,Wenjiao Fan et al.
Junyue Sun et al.
Microbeads (MBs) aggregation-based immunoassay, which is independent of multistep bead washing, signal labeling, and even reporter eluting procedures, has emerged as a promising label-free route for protein biomarker analysis. However, thei...
Exactly Matching the FRET Energy of the Functionalized Upconversion Nanoprobe to Boost the Sensing Performance toward Perchlorate [0.03%]
通过精确匹配FRET能量的功能化上转换纳米探针以增强其对高氯酸根的检测性能
Zhongfei Shang,Meimei Wang,Jiguang Li et al.
Zhongfei Shang et al.
The design and development of ultra-accurate probe is of great significance, but there is still a big challenge for chemical sensing in complex practical detection scenes. Here, a unique optical nanoprobe with high sensitivity and anti-inte...
Copper-Deficient Cu2- xSe/g-C3N4 Immobilizing Lactate Oxidase Cascade Catalytic Chemiluminescence for Lactate Detection [0.03%]
铜缺乏的Cu2-xSe/g-C3N4固定乳酸氧化酶级联催化化学发光检测乳酸
Xiaoxiao Li,Meihan Guo,Chenlei Gu et al.
Xiaoxiao Li et al.
Integrating distinct catalytic processes to develop novel cascade catalytic systems, thereby enhancing catalytic efficiency, holds significant promise for biosensing applications, owing to its superior advantages in signal transduction and ...
Split G-Quadruplex-Integrated CRISPR-Cas Biosensor for One-Pot, Signal-On Visual Detection of Pathogen Nucleic Acids [0.03%]
一种用于病原体核酸检测的一锅型信号开启视觉生物传感器
Yan Zhang,Yanan Lin,Ruoxuan Li et al.
Yan Zhang et al.
Pathogen nucleic acid analysis has emerged as an indispensable component of contemporary healthcare systems, serving dual roles in personalized clinical management and population-level disease surveillance. Herein, we present a novel G-quad...
Photothermal-Enhanced Desorption and Internally Heated Photochemical Ionization TOF-MS for Rapid and Quantitative Analysis of Particulate PAH Composition [0.03%]
光热增强解吸和内部加热光电离飞行时间质谱法快速定量分析颗粒物中多环芳烃化合物组成
Zhenming Wang,Jianwei Yang,Yingzhe Guo et al.
Zhenming Wang et al.
Fine particulate matter (such as PM2.5) is one of the most critical areas of atmospheric pollution, posing significant risks to the health of the respiratory, circulatory, and nervous systems. An immediate concern is the inadequate characte...
A Woundplast of Hydrogel Microneedles with In Vivo ATP-Responsive Therapeutic Logic for Bacteria-Infected Wound Healing [0.03%]
一种具有体内治疗逻辑的水凝胶微针创可贴用于细菌感染伤口修复
Yuzhu Li,Juanjuan Zhu,Cheng Wang et al.
Yuzhu Li et al.
To reduce the overuse of antibiotics, on-demand antibiotic administration guided by rapid infection assessment is of particular importance. In this study, we present a portable, multifunctional hydrogel microneedle (MN) woundplast capable o...
Development of an FDM-TDLAS Sensor for Long-Term Online Monitoring of H2S and CO to Predict Water Wall Corrosion Trends [0.03%]
用于长期在线监测H2S和CO以预测水壁腐蚀趋势的FDM-TDLAS传感器的研发
Xuanbing Qiu,Xiaohe Xiong,Long Li et al.
Xuanbing Qiu et al.
A laser sensor system was developed to be employed in power plants and specifically engineered for high-particulate and high-temperature environments to be applicable for the online monitoring of hydrogen sulfide (H2S) and carbon monoxide (...
Metal Ion Isotope Ratio Using ESI-Orbitrap HRMS: Proof of Concept and Initial Performance Evaluation for Lead Isotopic Ratios [0.03%]
基于ESI- Orbitrap高分辨质谱的金属同位素比分析：铅同位素比的原理证明及初步性能评估
Gianluca Roncoroni,Davide Spanu,Gilberto Binda et al.
Gianluca Roncoroni et al.
This study introduces a novel approach using an electrospray source coupled to an Orbitrap MS instrument to determine metal isotope ratios. The procedure involves forming a complex between the ion of interest and an appropriate ligand, gene...
Overcoming Matrix Effects in Non-Target Screening: A Novel Strategy for Urban Runoff Analysis [0.03%]
克服非目标筛查中的矩阵效应：城市地表径流分析的新策略
Thomas Molnár Karlsson,Jan H Christensen
Thomas Molnár Karlsson
Matrix effects (MEs) challenge the reliability of target and non-target screening (NTS) in urban runoff analysis, particularly due to sample heterogeneity, which makes pooled samples inadequate for method development, validation, and ME cor...
Facilely Fabricating Bimetallic Ir/Co Nanozymes with High Oxidize-like Activities for Sensitive Detection of Malathion with Portable Swabs [0.03%]
一种用于检测马拉硫磷的高氧化类似活性双金属Ir/Co纳米酶的简便合成方法及便携式拭子传感器
Menghan Liu,Ruyu Zhang,Jie Wang et al.
Menghan Liu et al.
Bimetallic nanozymes not only have strong synergistic catalysis ability but also may improve the catalytic specificity of the nanozymes. Herein, the oxidase (OXD)-mimic Ir/Co bimetallic nanozymes were prepared through a coordination reactio...