Josselyn Mata Calidonio,Kevin J Mathewson,Kimberly Hamad-Schifferli
Josselyn Mata Calidonio
Selective sensor arrays, commonly referred to as chemolfactory or "artificial nose" systems, have proven powerful in detecting and discriminating small molecules through cross-reactive, pattern-based recognition. While these systems have tr...
Efficient and Wide Chemical-Space Ionization of Organic Contaminants Using LC-MS with a Miniaturized Plasma Source Applying Different Discharge Gases [0.03%]
采用不同放电气体的微型等离子源LC-MS法有效而广泛地电离有机污染物化学空间
Irene Caño-Carrillo,Bienvenida Gilbert-López,David Moreno-González et al.
Irene Caño-Carrillo et al.
Dielectric barrier discharge ionization has gained significant interest due to its versatility and broad chemical coverage. Although electrospray ionization (ESI) is the most commonly used ionization source for organic contaminant analysis ...
A DNA Triangular Prism-Based Multitargeting Transistor for Ultrasensitive Detection of Respiratory Virus [0.03%]
基于DNA三角棱镜的多目标晶体管用于呼吸病毒超灵敏检测
Zhenhua Min,Jing Xie,Mengmeng Xiao et al.
Zhenhua Min et al.
The rapid and precise quantification of viral copies in clinical samples at extremely low concentrations is crucial for controlling infections and epidemics. The widely used nucleic acid detection methods require specialized equipment, high...
δ(18O/16O) Determinations in Water Using Inductively Coupled Plasma-Tandem Mass Spectrometry [0.03%]
基于ICP-MS的水体氧同位素比值分析研究
Shaun T Lancaster,Johanna Irrgeher,Remi Dallmayr et al.
Shaun T Lancaster et al.
A fully validated measurement approach for the determination of oxygen isotope ratios in water using inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS) is described for the first time. Deuterium was used as a reaction gas to ma...
ICP-MS for Multiplexed Protein Determination in Extracellular Vesicles from APP/PS1 Mice Blood Serum-Application to a Zn Supplementation Pilot Study [0.03%]
基于APP / PS1小鼠血清的ICP-MS在细胞外囊泡中进行蛋白多重检测及其在锌补充研究中的应用
Jaime Martínez-García,Beatriz Fernández,Enol Artime et al.
Jaime Martínez-García et al.
Neurodegenerative diseases represent a significant challenge due to their complex etiology, late diagnosis, and lack of effective treatments. Extracellular vesicles (EVs) have emerged as promising carriers of disease biomarkers, especially ...
Supramolecular Organic Framework-Enabled Aggregation-Enhanced Electrochemiluminescence for Ultrasensitive Detection of MMP 9 [0.03%]
超分子有机框架增强聚集型电化学发光用于超高灵敏度基质金属蛋白酶9检测
Yu Du,Hao Geng,Jingui Chen et al.
Yu Du et al.
The electrochemiluminescence (ECL) performance of tetraphenylethylene (TPE) derivatives benefits from their intrinsic aggregation-induced emission (AIE) characteristics. Under appropriate aggregation conditions, restricted intramolecular mo...
Securing the Future of NMR Metabolomics Reproducibility: A Call for Standardized Reporting [0.03%]
关于核磁共振元组学可重复性标准化报告的呼吁
Erik R Andersson,Amanda L Bayless,Robert B Brua et al.
Erik R Andersson et al.
Metabolomics is a rapidly growing multidisciplinary field with ever increasing demand and usability, which is attracting a surge of new researchers. While their varied skill sets, scientific questions, and approaches enrich the field with f...
Hydrogel-Bead Particles Enable Activity-Based Identification of Nucleic Acid Aptamer Enzyme Inhibitors [0.03%]
水凝胶微球使基于活性的小分子及核酸适配体酶抑制剂的筛选成为可能
Amanda A Nguyen,Brian M Paegel
Amanda A Nguyen
Nucleic acid aptamers bridge the gap between small molecules and antibodies as potentially nonimmunogenic, stable, selective, and potent ligands. Aptamer discovery starts with massively parallel affinity selection-driven directed evolution,...
Artificial Intelligence as a Scientific Copilot in Analytical Chemistry: Transforming How We Write, Review, and Publish [0.03%]
人工智能在分析化学中的科学协作作用：转变我们撰写、审稿和发表论文的方式
Adrián Fuente-Ballesteros,Victoria Samanidou,Seyed Mosayeb Daryanavard et al.
Adrián Fuente-Ballesteros et al.
Artificial intelligence (AI) is increasingly present across all phases of analytical chemistry, not only in experimental workflows but also in the way scientific writing is produced, evaluated, and published. This perspective offers a criti...
Multifunctional Co3O4@PDA Nanocomposite-Based Sensitive Dual-Mode Lateral Flow Immunoassay for the Simultaneous Detection of Two Antibodies against Respiratory Tract Pathogens [0.03%]
一种用于同时检测呼吸道病原体两种抗体的多功能Co3O4@PDA纳米复合材料基敏感型双模式层析免疫检测试纸
Tao Dong,Guangze Sun,Wanjian Liu et al.
Tao Dong et al.
Acute respiratory infections (ARIs) are among the leading causes of morbidity and mortality worldwide, with Mycoplasma pneumoniae (M. pneumoniae) and Chlamydia pneumoniae (C. pneumoniae) being major pathogens responsible for community-acqui...