Convergence of Multimodal Biosensors and Microfluidics in Point-of-Care Diagnostics: Translating Innovations into Next-Generation Healthcare [0.03%]
Yahui Chen,Enqi Sun,Yuchen Sun et al.
Yahui Chen et al.
Side-Port Puncture Needle-Assisted, Multistep Vacuum-Driven Microfluidic Chip for Multiplexed Molecular Analysis [0.03%]
Chunyang Geng,Xiangtao Shi,Yingmin Zeng et al.
Chunyang Geng et al.
The development of microfluidic chips for biological and chemical applications is a rapidly evolving field because these devices can perform a complex set of sequential operations on a submillimeter scale. Here, we develop a vacuum-driven m...
Efficient and Selective Arsine Evolution Reaction on the VS4- x-Modified Electrode for Atomic Spectroscopic Quantification of Sub-ppb Level AsIII [0.03%]
Li-Li Yao,Wang-Jia Xia,Xin-An Yang et al.
Li-Li Yao et al.
Atomic spectroscopy technology is the gold standard for quantifying heavy metal elements; however, challenges persist in identifying element forms due to the mechanism of spectral line generation. Herein, we proposed an electrolytic hydride...
Intelligent Wearable Fluorescence Hydrogel-Imprinted Sensor for Rapid Noninvasive Simultaneous Detection of Capecitabine and 5-Fluorouracil in Sweat [0.03%]
Ruoyan Wang,Ao Ma,Qiuyu Wu et al.
Ruoyan Wang et al.
Therapeutic drug monitoring of anticancer drugs is crucial to advancing personalized medicine. This study developed a wearable fluorescence hydrogel-imprinted sensor integrated with automated smartphone-based image processing of fluorescenc...
Spin-Selective Charge Modulation in a Chiral Topological Heterojunction for Ultrasensitive Photoelectrochemical Detection of Polyvinyl Chloride [0.03%]
Li Shan,Yu Liang,Ziyan Fan et al.
Li Shan et al.
Efficient suppression of carrier recombination is crucial for enhancing the performance of photoelectrochemical (PEC) biosensors. Here, we engineered a chiral molecule-modified BiOI/ZIF-8 (BZ) heterojunction in which the carrier separation ...
Siqi Wang,Yuru Jiao,Chao Zhang et al.
Siqi Wang et al.
It is generally believed that the practical application of aptamers in food safety monitoring is often hindered by their attenuated performance in complex, crowded food matrices. As a fundamental characteristic of realistic sample matrices,...
Interfacial Hybridization-Enabled Chemiresistive Detection of Battery Electrolyte Vapors under Humid Conditions Using Polyoxometalate-Derived Dendritic WO3/Au Sensors [0.03%]
Xiaoqian Kuang,Jingyan Tang,Li Chen et al.
Xiaoqian Kuang et al.
Electrolyte leakage from lithium-ion batteries constitutes a critical safety challenge as volatile and highly flammable organic carbonates can rapidly trigger fire and catastrophic thermal runaway. Diethyl carbonate (DEC), a widely used ele...
A Sugaromics Method for Combined Targeted and Untargeted Sugar Profiling: Fit-for-Purpose Validation of a Quantitative GC × GC-MS Approach [0.03%]
Elisa E Streitenberger,Björn Egert,Lara Frommherz et al.
Elisa E Streitenberger et al.
The composition of sugar compounds in human biofluids is affected by various factors, including diet, health, demographic background, and lifestyle. Accurate quantification of this profile enables identification and application of biomarker...
Protein-Corona-Based Nanomagnetic Enrichment Strategy for In-Depth Secretome Profiling of Lung Adenocarcinoma Organoids [0.03%]
Wenhui Wu,Yuebo Zhang,Zizhang Guo et al.
Wenhui Wu et al.
Secreted proteins are critical mediators of intercellular communication that shape the tumor microenvironment (TME). While patient-derived organoids (PDOs) provide physiologically relevant models that preserve patient heterogeneity, compreh...
Aishwarya Patel,Krish Janmejay Patel,Simona Clement et al.
Aishwarya Patel et al.
Ionophore-based ion-selective optodes, together with ion-selective electrodes, constitute a highly selective class of chemical sensors for detecting ionic species such as electrolytes. The choice of water-immiscible matrix in these sensors ...