Targeted Affinity Screening Approach for Bioactive Compounds in Curcuma longa Utilizing a Cell-Functionalized Hydrogel [0.03%]
基于细胞功能化水凝胶的靶向亲和筛选姜黄中活性化合物的新方法
Meihui Zhang,Xiaxi Zhang,Xinyue Yang et al.
Meihui Zhang et al.
Selective discovery of receptor-binding ligands from complex natural matrices remains a significant analytical challenge for bioactive compound identification and lead discovery. Herein, a three-dimensional biomimetic screening strategy was...
Process-Aware Deep Learning for Low-Cost Greenhouse Gas Sensing: Insights from Composting toward Scalable Anthropogenic Activities Applications [0.03%]
面向流程的深度学习在低成本温室气体检测中的应用：从堆肥到可扩展的人为活动应用程序的见解
Zhonghao He,Haihong Jiang,Jing He et al.
Zhonghao He et al.
Greenhouse gases (GHGs) monitoring is essential for mitigating emissions from anthropogenic activities, yet the deployment of high-precision analyzers remains constrained by cost and operational complexity. Low-cost GHGs sensors often suffe...
Correction to "Precision Visualization of Tumor Microenvironment via a Lysosome-Anchored Molecular Rotor with Viscosity-Triggered Fluorescence Ignition" [0.03%]
“基于溶酶体固定分子马达的肿瘤微环境精准成像”一文的勘误通知
Ning Ding,Bochao Chen,Feifei Jiang et al.
Ning Ding et al.
Published Erratum
Analytical chemistry. 2026 Jul 26. DOI:10.1021/acs.analchem.6c04612 2026
DNA Nanowire-Assisted CRISPR/Cas12a Triple Cascade Amplification for Sensitive Detection of Myeloperoxidase Activity [0.03%]
基于DNA纳米线的CRISPR/Cas12a三联级联扩增技术用于髓过氧化物酶活性灵敏检测
Jia-Yi Shi,Shun-Li Wu,Yan Tan et al.
Jia-Yi Shi et al.
Myeloperoxidase (MPO) is an inflammation-associated heme enzyme implicated in cardiovascular oxidative stress, but sensitive activity-based detection in complex clinical samples remains challenging. Herein, we report a CRISPR/Cas12a-based t...
Biomimetic Neurostimulation Framework for Probing Bacterial Metabolism with Anisotropic Au@PDA Nanoassemblies [0.03%]
各向异性Au@PDA纳米组装体探测细菌代谢的仿生神经刺激框架
Kun Yan,Zongrun Zhang,Xianzhu Yang et al.
Kun Yan et al.
Microbial contamination poses significant risks, urgently requiring ultrasensitive and highly selective detection methods that are practical for real-world use. Inspired by the nervous system, we report anisotropic gold-polydopamine (Au@PDA...
Ultrasensitive Detection of Tumor-Derived Extracellular Vesicle microRNAs via Aptamer-Driven Targeted Membrane Fusion and Nonenzymatic Amplification [0.03%]
基于适配体驱动膜融合和非酶扩增的超灵敏检测肿瘤来源外泌体中的microRNA
Ruixiao Peng,Weirong Xiao,Xiaodong Xu et al.
Ruixiao Peng et al.
Extracellular vesicles (EVs) have emerged as a prominent and rapidly evolving class of biomarkers, garnering an increasing amount of attention in recent years. The analysis of diverse EV-derived biomolecules, including proteins, mRNA, and m...
Label-Free Evaluation of Advanced Glycation End Products by a Comprehensive Biophysical Analysis [0.03%]
基于生物物理综合分析的无标记评价食物中的晚期糖基化终产物
Ameera K,Darshan Chikkanayakanahalli Mukunda,Subhash Chandra et al.
Ameera K et al.
Nonenzymatic glycation is a post-translational modification of proteins, leading to the formation of advanced glycation end products (AGEs) implicated in diabetes, neurodegenerative disorders (NDDs), and aging-related complications. The sen...
AI-Integrated Molecularly Imprinted Gate-Controlled Nanozyme-Based Field-Deployable Multimodal Assay of Per- and Polyfluoroalkyl Substances in Environmental Waters [0.03%]
基于人工智能集成分子印迹的纳米酶门控式环境水中全氟和多氟化合物现场检测装置
Fengjiao He,Yimiao Zhang,Linpin Luo et al.
Fengjiao He et al.
The significant risks posed by per- and polyfluoroalkyl substances (PFAS) to water quality and public health have attracted increasing attention as a class of emerging contaminants. Efficient onsite assay of PFAS in environmental waters is ...
Time-Frequency Domain In Situ NMR: A Direct Probe into the Dynamics of Pulsed Electrocatalysis [0.03%]
时频域原位核磁共振：脉冲电催化的直接探测工具
Zi-Hao Ye,Ke-Xin Jin,Li-Na Wang et al.
Zi-Hao Ye et al.
Understanding the complex dynamics of organic electrocatalytic oxidation is essential to advancing sustainable energy technologies. This study presents an in situ methodology that integrates square-wave-pulsed electrolysis with electrochemi...
Conformal L012-Gold Nanoparticles/Laser-Induced Graphene Interfaces-Based Flexible Electrochemiluminescence Array for Multiplexed Detection of Sweat Metabolites [0.03%]
用于汗代谢物多路检测的基于共形L012-金纳米粒子/激光诱导石墨烯界面的柔性电化学发光阵列
Wei Nie,Linfeng Zhuo,Jinrong Liu et al.
Wei Nie et al.
Electrochemiluminescence (ECL) holds promise for wearable multiplexed sweat sensing due to its high sensitivity, broad linear dynamic range, and inherent capacity for parallel signal acquisition through electrochemical-to-optical conversion...