Highly Discriminative Detection of Nitrophenol Isomers by Covalent Organic Framework Membrane-Modified Electrochemical Sensors [0.03%]
基于共价有机框架膜修饰的电化学生物传感器检测硝基酚异构体
Nuo Dong,Jiayi Cao,Xinru Li et al.
Nuo Dong et al.
Nitrophenol isomers (NPs), namely, ortho-, meta-, and para-nitrophenol (o-NP, m-NP, and p-NP) are an important class of organic compounds widely employed in industrial fields. Due to their high chemical stability, resistance to natural degr...
Tailoring a Dual-Response Site Ratiometric Luminescent Probe Based on a Ruthenium(II) Complex-Benzothiazole Scaffold for Monitoring Intracellular pH Changes [0.03%]
基于钌(ii)配合物-苯并噻唑骨架的双模响应型比值型发光探针的构建及细胞内ph变化监测研究
Junyu Ren,Wenzhu Zhang,Xiaona Gao et al.
Junyu Ren et al.
Organelle-specific pH represents a crucial parameter associated with cellular homeostasis and pathological conditions. Dysregulated intracellular pH has been manifested in a myriad of diseases. Ratiometric luminescence imaging enables preci...
In Situ Variable-Temperature Liquid ToF-SIMS Enables Molecular Investigation of Supercooled Water-in-Salt Electrolytes [0.03%]
原位变温液相ToF-SIMS揭示过冷水合电解质中盐的分子结构及分布规律
Yuxin Liu,Jie Cui,Junfeng Xiang et al.
Yuxin Liu et al.
The microstructures, including ion solvation structures and water structures within supercooled water-in-salt electrolytes, determine macroscopic properties of electrolytes, such as ion conductivity, viscosity, and freezing point, thereby a...
Enhanced Structural Understanding of Dissolved Organic Matter through Comparative LC/MS2 Analysis with Synthetic Carboxylate Rich Alicyclic Molecules [0.03%]
通过含有丰富羧基的环状合成分子进行比较性LC/MS2分析增强对溶解性有机质结构的理解
Jeffrey A Hawkes,Agnes D Flygare,Lindon W K Moodie et al.
Jeffrey A Hawkes et al.
Dissolved organic matter (DOM) is one of the most complex chemical mixtures known, with its chemical composition having long puzzled biogeochemists. Identifying the chemical structures within DOM is essential for unraveling its origins and ...
Exploring the Potential of Chemically Matched Fragments as Internal Standards for Quantitative SERS with Panobinostat [0.03%]
探究化学匹配片段作为定量表面增强拉曼光谱(SERS)内标的潜力——以帕那滨为例
Yiming Huang,Yikai Xu,Chunchun Li et al.
Yiming Huang et al.
Surface-enhanced Raman spectroscopy (SERS) has great potential for therapeutic drug monitoring (TDM) due to its high sensitivity; however, achieving accurate and robust quantitative data remains challenging. The most effective approach for ...
An Ultra-High Throughput Cell-Based Mass Spectrometry Flux Assay as a Pathway-Selective In Situ Screening Approach [0.03%]
一种基于细胞的超高通量质谱流式检测法作为途径选择性体内筛选方法
Daniel P Downes,Christopher M Barbieri,David Connors et al.
Daniel P Downes et al.
Acoustic ejection mass spectrometry (Echo-MS) is a viable biochemical screening platform enabling direct detection of biologically relevant enzymatic activities with throughput approaching or meeting the cycle time of conventional optical r...
Integrating Thiolated Mass Tags with Immuno-Mass Spectrometry Imaging to Map the Spatial Signatures of Functional Proteins in Cancer Tissues [0.03%]
含有硫醇的亲免疫组学质量标签在癌症组织中绘制功能蛋白空间标记方面的应用
Xiaoqing Cui,Shiping Chen,Haoyuan Geng et al.
Xiaoqing Cui et al.
Cancer cells are marked by metabolic reprogramming. Mapping metabolites and their related functional proteins contributes to a comprehensive understanding of metabolic regulation during cancer progression. Mass spectrometry imaging enables ...
Time-Correlated Raman Spectroscopy (TCRS): Enhancing Single-Cell Bacterial Detection through Temporal Variation Analysis [0.03%]
时间相关拉曼光谱(TCRS)：通过时间变化分析增强单细胞细菌检测
Qifeng Li,Hua Xia,Yi Sun et al.
Qifeng Li et al.
Rapid detection of bacteria is crucial for mitigating the risks associated with bacterial contamination. Raman spectroscopy has emerged as a promising technique for single-cell bacterial identification. However, the Raman signals of single ...
GA-HIDMS-PSO-BPNN Model-Based Suppression of Cross-Interference in Absorption Spectra for Dual-Gas Sensing [0.03%]
基于GA-HIDMS-PSO-BPNN模型的吸收光谱交叉干扰抑制方法研究
Tingting Zhang,Chunsheng Li,Yiwen Feng et al.
Tingting Zhang et al.
Cross-interference from overlapping absorption spectra of different gases significantly limits the precision and stability of gas concentration detection using traditional absorption spectroscopy. This study proposes a novel model integrati...
High-Precision Electrophoretic Mobility Measurements of Single Particles and Red Blood Cells Using High-Voltage Microfluidic Transverse AC Electrophoresis (HV-TrACE) [0.03%]
基于高压横向交流电泳的单颗粒和红细胞高精度等效移动度测量技术(HV-TrACE)
M Hannah Choi,Dayi Chen,Samaneh Zare-Harofteh et al.
M Hannah Choi et al.
Single-particle characterization is essential for understanding the behavior and interactions of particles, particularly in biological contexts where changes in physical properties can influence their biological functions. However, current ...