Laser-Printed Electrochemical Microfluidic Aptasensing Chip for Simultaneous Detection of Multiple Pesticides [0.03%]
激光打印的电化学微流体适配子芯片同时检测多种农药
Xiaojuan Liu,Jiahui Zhao,Qinxing Sun et al.
Xiaojuan Liu et al.
Laser scribing-based nanotechnology shows superior performance in the precise and scalable construction of customized sensors. In light of the significant threats posed by pesticide residues to food safety and ecological sustainability, pro...
The New Scanning Mode in Digital Linear Ion Trap Mass Spectrometry for the Detection of New Psychoactive Substances in E-Cigarette Oils [0.03%]
新一代数字线性离子阱质谱扫描模式在电子烟油中新型精神活性物质检测中的应用研究
Sen Tian,Jiecong Lu,Yunjing Zhang et al.
Sen Tian et al.
The abuse of new psychoactive substances (NPS) has become a growing global concern, and their illegal addition to commercial e-cigarette oils poses severe threats to human health and potentially results in fatalities. Regulatory control of ...
Live-Cell Imaging and Lipidomics of Low-Density Lipoprotein Containing Intrinsically Fluorescent Cholesteryl Esters [0.03%]
含固有荧光胆固醇酯的低密度脂蛋白的活细胞成像和脂质组学研究
Alice Dupont Juhl,Richard R Sprenger,Maciej Modzel et al.
Alice Dupont Juhl et al.
Low-density lipoprotein (LDL) delivers cholesterol to mammalian cells in the form of cholesteryl esters (CEs), but due to the lack of suitable tools, our understanding of the intracellular transport and hydrolysis of CEs is limited. We pres...
Grayscale-Element Bayesian Method Based on Synchrotron Radiation Nano-CT: Quantitative Characterization of Elemental Content and Heterogeneity [0.03%]
基于同步辐射纳米CT的灰度元素Bayesian方法及其定量表征元素含量及异质性分布研究
Yichi Zhang,Fen Tao,Ruoyang Gao et al.
Yichi Zhang et al.
Achieving nondestructive, high-precision quantitative elemental analysis at the nanoscale has long been a challenge in materials characterization. The proposed Grayscale Bayesian Elemental Quantification Analysis (GBEQA) method effectively ...
Electrochemiluminescence Biosensor Based on Dual-Signal Regulation of Gold Nanoclusters for Amyloid-β Protein Detection [0.03%]
基于金纳米团簇双信号调控的电化学发光生物传感器检测淀粉样蛋白-Aβ
Qingfei He,Lingjun Cheng,Yuanyuan Yang et al.
Qingfei He et al.
Gold nanoclusters (AuNCs) are emerging electrochemiluminescence (ECL) emitters with unique luminescence and high stability. However, conventional AuNC-based ECL systems, which rely on single-signal regulation, often exhibit weak signal resp...
Nanofluidic Photoelectrochemical Biosensors for Ultrasensitive Detection of Prostate Cancer Biomarkers [0.03%]
用于超灵敏检测前列腺癌生物标志物的纳米流体光电化学生物传感器
Xudong Yang,Linge Chen,Yilong Wang et al.
Xudong Yang et al.
Significant advances have been made in nanofluidic biosensors for the highly efficient detection of disease biomarkers in complex biofluids. However, most research efforts have primarily focused on external voltage-driven sensing mechanisms...
Deconvolution of High-Dimensional Ion Mobility Data Using Reversible-Jump Markov Chain Monte Carlo [0.03%]
基于可逆跳跃马尔可夫链蒙特卡洛的高维离子淌度数据脱卷积
Jerome Riedel,Marc Safferthal,Gergo Peter Szekeres et al.
Jerome Riedel et al.
Deconvolution of multicomponent arrival time distributions is known to be a highly challenging task due to the "curse of dimensionality". Therefore, the development of a robust global optimizer is a crucial milestone in the automated analys...
From Spectral Interference to Overlapped Features: A Full-Spectrum LIBS Voigt Decomposition Strategy with Shoulder Detection and Residual Completion [0.03%]
从光谱干扰到重叠特征——一种肩峰检测和残差补全的全谱LIBS伏特分解策略
Panyang Dai,Peichao Zheng,Jinmei Wang et al.
Panyang Dai et al.
Laser-induced breakdown spectroscopy (LIBS) provides rapid, multielement analysis of complex alloys, but dense line crowding, limited resolution, and plasma broadening cause strong spectral interference and overlapping features that degrade...
SILICO-MS: Exploring Structural Lipidomic Alterations Using an Ionization-Coupled Ozonolysis Mass Spectrometry Strategy [0.03%]
基于电喷雾解离与臭氧裂解联用的脂质组学结构信息研究
Jingshen Xu,Xiaoyan Xu,Xiaohan Hou et al.
Jingshen Xu et al.
Lipid structural characters especially the positions of carbon-carbon (C═C) double bonds are closely associated with multiple biochemical processes and biophysical properties such as structural membrane packing, membrane fluidity, interlea...
Revealing the Spatial-Molecular Fingerprint of BMP4 Expression in Breast Cancer Using ToF-SIMS and Multiple Instance Learning [0.03%]
基于ToF-SIMS和多重实例学习揭示BMP4在乳腺癌中的空间分子特征
Wil Gardner,Judy Borg,Kellie A Mouchemore et al.
Wil Gardner et al.
Hyperspectral materials characterization techniques are becoming ubiquitous and technologically more sophisticated. There has been widespread development and application of machine/statistical learning to better understand large hyperspectr...