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期刊名:Analytical chemistry

缩写:ANAL CHEM

ISSN:0003-2700

e-ISSN:1520-6882

IF/分区:6.7/Q1

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Andrea Cabrero-Martín,Víctor Ruiz-Valdepeñas Montiel,Rebeca M Torrente-Rodríguez et al. Andrea Cabrero-Martín et al.
This work reports the first electroanalytical methodology developed to determine global levels of G-quadruplex (G4) motifs in DNA, hitherto underestimated noncanonical structures of increasing relevance both in cancer diagnostics and precis...
Wei Liu,Jiayu Tang,Guoquan Yan et al. Wei Liu et al.
Protein complexes are central to cellular function and respond rapidly to pharmacological perturbations. Co-fractionation mass spectrometry (CoFrac-MS) is widely employed to analyze protein complexes by analyzing individual chromatographic ...
Haoyi Ren,Yingying Cheng,Yige Li et al. Haoyi Ren et al.
Electrochemiluminescence (ECL) immunosensors are widely used for cancer marker detection due to their high selectivity, but their reuse is limited by the need for electrode reconditioning after each assay, hindering large-scale application....
Xingchun Zhai,Junjie Li,Weiwei Cheng et al. Xingchun Zhai et al.
This study introduces a radial-hierarchical, diffusion-enhanced spatiotemporal sensing paradigm for volatile organic compound (VOC) analysis via an integrated microchamber paper-based chromatomimetic e-nose. The proposed system synergizes i...
Ruili Li,Shuting Huang,Shenghong Liu et al. Ruili Li et al.
Nanoplastics (NPs) and their aged counterparts (aNPs) pose growing environmental and health risks; however, their impact on cellular redox homeostasis remains poorly understood due to the difficulty in simultaneously assessing the amounts o...
Aipeng Chen,Fangzhou Lan,Yue Ding et al. Aipeng Chen et al.
MicroRNAs (miRNAs) packaged within extracellular vesicles (EV) exhibit remarkable stability in circulation and reflect the genetic and epigenetic characteristics of their parent cells, making them promising biomarkers for cancer diagnosis. ...
Yang Yang,Jie Zhang,Zongyang Li et al. Yang Yang et al.
Diabetes mellitus is a chronic metabolic disorder associated with persistent hyperglycemia, leading to severe complications affecting multiple organs, particularly the liver and wound healing processes. One major factor driving these compli...
Noemi Bellassai,Anil Biricik,Matteo Surdo et al. Noemi Bellassai et al.
In vitro fertilization (IVF) faces challenges in evaluating embryo quality and in determining the genetic health of embryos. Key biomarkers in the culture medium, including nucleic acids and proteins, offer promising avenues for noninvasive...
Qingqing Shen,Wang Cao,Ming Zhang et al. Qingqing Shen et al.
Accurately measuring circulating proinsulin proteoforms is crucial for clinical investigation of diabetes, but was previously not feasible owing to limited assay specificity/sensitivity. Here we devised a highly sensitive LC-MS-based strate...