Refractive Index of Benchmark Polystyrene Nanoplastics by Optical Modeling of UV-Vis Spectra [0.03%]
基于紫外可见光谱光学建模的聚苯乙烯纳米塑料基准物质的折射率
Mattia Andrini,Stefania Federici,Luca Gavioli
Mattia Andrini
Optical recognition and identification of nanoplastics such as polystyrene nanobeads (PSbs), a widely used polymer and an actual source of environmental pollution, is a challenging task relying on knowledge of the PSbs' refractive index (RI...
Transcriptome Analysis of Tear-Derived Extracellular Vesicles as Biomarkers for Diabetic Retinopathy [0.03%]
糖尿病性视网膜病变的泪液衍生外泌体转录组分析作为生物标志物研究
Jiaming Chen,Zhaowei Zhang,Xiaoqin Hong et al.
Jiaming Chen et al.
Diabetic retinopathy (DR) represents the predominant etiology of visual impairment and blindness on a global scale. At present, there is still a dearth of robust biomarkers for DR, which substantially limits its diagnosis, particularly at a...
Bromine-Functionalized Covalent Organic Frameworks Enhancing the Desorption Efficiency and Enabling Preconcentration of Brominated Pollutants for Mass Spectrometry Detection [0.03%]
用于质量检测的溴化污染物预富集的增强脱附效率的 bromine-功能化的共价有机框架
Yong Tian,Ruijie Zhao,Yanfeng Zhang et al.
Yong Tian et al.
Covalent organic frameworks (COFs) exhibit exceptional adsorption capacity but suffer from challenging desorption. In this study, a bromine-functionalized magnetic COF composite (Fe3O4@COF-Br) was synthesized via bromodimethylsulfonium brom...
Dendritic Mesoporous SiO2-Based SERS-Nanozyme-Mediated Immunochromatographic Detection of Foodborne Viruses with Enhanced Sensitivity across Multiple Scenarios [0.03%]
基于树突状介孔SiO₂的SERS-纳米酶增强型免疫层析试纸条法多重场景下检测食源性病毒
Jiaxuan Li,Qing Yu,Zhengkang Li et al.
Jiaxuan Li et al.
Detecting low-concentration foodborne viruses in complex samples has long posed a great challenge. Here, we propose a colorimetric enhancement-surface-enhanced Raman scattering (SERS) quantitative dual-mode immunochromatographic assay (ICA)...
Dual-Functional Microneedles for In Situ Diagnosis and Biofilm-Targeted Therapy of Diabetic Periodontitis via Biomarker-Responsive Probes and Photothermal NO Nanomotors [0.03%]
基于生物标志物响应型探针和光热NO纳米马达的就地诊断与牙周病生物膜靶向治疗多功能微针
Jinze Li,Qin Xiang,Guolong Zhao et al.
Jinze Li et al.
Chronic periodontitis, a frequent complication of diabetes, is exacerbated by bacterial biofilms that drive progressive periodontal tissue destruction and systemic inflammation. Conventional treatments, utilizing mechanical debridement and ...
Synergistic Coupling of Antenna Effect and Schottky Junction in Tb-Doped Covalent Organic Framework for Enhanced Electrochemiluminescence Sening of Isobutyryl Fentanyl [0.03%]
铽掺杂共价有机框架中天线效应与肖特基结的协同作用用于异丁酰芬太尔电致化学发光检测增强
Bingxue Fan,Ding Jiang,Yuan Ni et al.
Bingxue Fan et al.
Rational design of both mechanistic pathways and material compositions is essential to advance COF-based electrochemiluminescence (ECL) systems. In this study, aggregation-induced emission covalent organic framework (AIE-COF) nanoprobes wit...
Near Infrared-Responsive Xanthene Probes for Dual-Mode Cancer Treatment and Bioimaging [0.03%]
用于癌症诊疗的近红外响应型香豆素探针
Junfeng Zhang,Lingyu Jin,Bin Xiao et al.
Junfeng Zhang et al.
The incidence of cancer has escalated at a distressing pace, creating an urgent demand for advancements and breakthroughs in medical interventions. Amidst the multitude of approaches for diagnosing and managing cancer, fluorescence imaging,...
Thioflavin T Is a More General and Less Interfering Probe for Aptamer Binding Assays Than SYBR Green I [0.03%]
姜黄素蛋白T是一种比SYBR绿色I更通用且干扰性更低的适配子结合测定探针
Yun Shu,Shiyuan Liu,Juewen Liu
Yun Shu
Label-free fluorescent binding assays employing DNA staining dyes as probes are widely adopted techniques in the aptamer field. While many dyes have been used, thioflavin T (ThT) did not receive much attention for this purpose until recentl...
Tetrahedral DNA Framework-Engineered Magnetic Nanozyme for Visual Biomarker Sensing via Alkaline Phosphatase-Triggered Signal Switching [0.03%]
基于四面体DNA框架工程的磁纳米酶通过碱性磷酸酶触发信号切换用于视觉生物标志物检测
Mengde Zhao,Jiahui Zhang,Lihua Wang et al.
Mengde Zhao et al.
Point-of-care (POC) detection of prostate-specific antigen (PSA) is critical for the early screening and monitoring of prostate cancer (PCa), which facilitates timely intervention and personalized treatment. However, existing POC platforms ...
Atomic Engineering of a FeFe Dual Single-Atom Nanozyme for Enhanced Peroxidase-like Activities To Build Chemical Tongue for Discrimination of Aromatic Amines [0.03%]
用于构建区分芳香胺化学舌的铁原子酶Dual单原子纳米酶的原子工程学研究
Jingyuan Guo,Guo Wang,Yunfan She et al.
Jingyuan Guo et al.
Single-atom nanozymes have made important progress in the field of sensors, but their catalytic performance as natural enzyme substitutes is far from satisfactory. We describe here a FeFe dual single-atom nanozyme (Fe2N6/CN) with a Fe loadi...