Rapid 13C Solid-State Quantitative NMR Method for Multiple Physical and Chemical Analyses of Cocoa-Based Products: Proof of Concept [0.03%]
用于基于可可产品的多种物理和化学分析的快速13C固态定量NMR方法：概念证明
Thais Juliana Tobias,Priscilla Efraim,Tiago Bueno de Moraes et al.
Thais Juliana Tobias et al.
Chocolates and other cocoa products represent a multibillion-dollar industry that has faced significant price increases, largely due to a surge in cocoa plant diseases linked to climate change. One potential solution for mitigating cocoa pr...
Rapid Copolymer Analysis of Unresolved Mass Spectra by Artificial Intelligence [0.03%]
基于人工智能的快速解析不可分辨质谱共聚物组成分布的方法学研究
Gergő Róth,Ákos Kuki,Aron Kipyegon Rop et al.
Gergő Róth et al.
In this Article, we present a novel data analysis method for the determination of copolymer composition from low-resolution mass spectra, such as those recorded in the linear mode of time-of-flight (TOF) mass analyzers. Our approach signifi...
Kinetic and Mechanistic Discrepancies of Single/Dual-Atom Nanozymes Drive a Triple-Channel Sensing Array for Machine Learning-Assisted Antioxidant Discrimination [0.03%]
单/双原子纳米酶的动力学和机制差异驱动用于机器学习辅助抗氧化剂鉴别的三通道传感阵列
Xianyong Shen,Shirui Ma,Chuncan Song et al.
Xianyong Shen et al.
Current colorimetric sensing arrays for antioxidant detection often struggle with discrimination due to cross-reactive signals from individual nanozymes. These signals are typically modulated by external factors such as pH or chromogenic su...
Chemical Tagging with Mass Spectrometry Analysis for Sensitive Determination of Carboxylic Enantiomers in Hepatic Fibrosis [0.03%]
基于质谱分析的化学标记法Sensitive测定肝纤维化组织中的羧酸对映异构体
Yu-Han Dai,Jun Zhang,Yi Gong et al.
Yu-Han Dai et al.
Carboxylic enantiomers are prevalent in living organisms and synthetic samples that exhibit important biological properties. The profiling of carboxylic enantiomers is beneficial for monitoring physiological states and further unraveling th...
Liquid Crystal Sensor Harnessing a Biomimetic Acetylcholinesterase Nanozyme for Detection of Trypsin in Human Serum [0.03%]
一种利用仿生乙酰胆碱酯酶纳米酶的液晶传感器用于检测人血清中的胰蛋白酶
Lili Wang,Wenli Wu,Binglu Zhao et al.
Lili Wang et al.
Abnormal levels of trypsin in the human body can lead to various diseases, yet conventional detection methods often lack operational simplicity and real-time readout capabilities. This work presents a state-of-the-art metal organic framewor...
Super-Resolution Imaging Captures Mitophagy Dynamics: Tricolor Fluorescence Labels Mitochondria, Autophagosomes, and Lysosomes [0.03%]
超分辨率成像捕捉线粒体自噬动力学：三色荧光标记线粒体、自噬体和溶酶体
Weikang Peng,Mei Li,Wenwen Li et al.
Weikang Peng et al.
Mitophagy is a vital lysosome-dependent process in which damaged mitochondria exhibiting elevated H2O2 production are selectively engulfed by autophagosomes and delivered to lysosomes for degradation, thereby maintaining intracellular homeo...
Ligand Engineering-Based High-Efficiency Photothermal Sensors Powered Sensitive Lateral Flow Immunoassay Platform [0.03%]
基于配体工程的高效光热传感器驱动灵敏侧流免疫测定平台
Zongyou Chen,Jiaqi Yin,Shijin Huang et al.
Zongyou Chen et al.
The photothermal lateral flow immunoassay (LFIA) has garnered considerable attention, owing to its suitability for on-site quantitative detection. Furthermore, it has distinct advantages in further constructing sensitive detection methods f...
Development of a Liposome-Based Serological Assay for SARS-CoV-2 Variants with Special Emphasis on Coupling Chemistries Required to Maintain Protein Antigenicity [0.03%]
基于脂质体的SARS-CoV-2变异株血清学检测方法开发及其对维持蛋白抗原性的偶联化学工艺要求分析
Simon Streif,Patrick Neckermann,Kilian Hoecherl et al.
Simon Streif et al.
The conjugation of proteins to the outer membranes of liposomes is a standard procedure used in bioanalytical and drug delivery approaches. Herein, we describe the development of a liposome-based surrogate assay for the quantification of SA...
Hollow Cu/Pt Interspersed GO Nanosheets Cascade Triggering Catalytic Signal Amplification for Colorimetric/SERS Sensing of Klebsiella pneumoniae in Clinical Samples [0.03%]
空心Cu/Pt间夹GO纳米片级联触发催化信号放大用于临床样本中肺炎克雷伯氏菌的比色/SERS检测
Xinjie Guo,Li Zhao,Yunchuan Jiang et al.
Xinjie Guo et al.
Rapid and precise detection of Klebsiella pneumoniae (K. pneumoniae) is crucial for early diagnosis, treatment of infectious ailments, and controlling outbreaks. Herein, we present a rapid, streamlined, and sensitive method for K. pneumonia...
Extending the Linear Dynamic Range of Single Particle ICP-MS for the Quantification of Microplastics [0.03%]
扩展单颗粒ICP-MS线性动态范围以定量分析微塑料
George C Caceres,Monique E Johnson,John L Molloy et al.
George C Caceres et al.
In response to the growing concern of microplastics (1 μm to 5 mm) accumulation affecting human health, the development of analytical methods continues to be critical for the detection and characterization of microplastic particles. In thi...