Surface Fluorination Engineering of FeCo Prussian Blue Analogs with Boosted Peroxidase-Like Activity and Selectivity: An Integrated Nanozyme-Membrane Sensing Platform for Perfluorooctanesulfonate [0.03%]
具有增强的类过氧化物酶活性和选择性的FeCo类普鲁士蓝类似物表面氟化工程：用于全氟辛烷磺酸检测的一体化纳米酶-膜传感平台
Xu Zhu,Ningning Liang,Ziyang Zhang et al.
Xu Zhu et al.
Accurate and sensitive analysis of perfluorooctanesulfonate (PFOS) is essential for environmental pollution traceability and risk assessment. Herein, a surface fluorination engineering strategy was proposed to construct fluorinated FeCo Pru...
Jiayue Yuan,Siyuan Wang,Yujin Wu et al.
Jiayue Yuan et al.
Molecular magnets, such as endohedral fullerenes and organic radicals, exhibit long quantum coherence times and thus serve as promising building blocks for molecular spin qubit systems. Given the stringent requirements of the magnetic envir...
A Spatial Coding Strategy for In Situ Visualization of RNA-Specific Glycoforms [0.03%]
用于RNA特异性糖型的原位可视化的一种空间编码策略
Ben Niu,Shuang Xie,Ruijia Deng et al.
Ben Niu et al.
Visualization of site specific glycoforms of RNA on live cell surfaces remains technically challenging due to glycoform heterogeneity and the covalently linked structural motifs of glycoRNA. Here, a spatial coding strategy termed SpaceFRET ...
Culture-Free Microfluidics for Ultra-Rapid Antimicrobial Susceptibility Testing with AI in Resource-Limited Settings [0.03%]
适用于资源匮乏地区的基于人工智能的微流体平台用于快速抗菌药物敏感性试验
Chao Wan,Huijuan Yuan,Chenxi Dai et al.
Chao Wan et al.
The misuse of antibiotics has accelerated the rise of antimicrobial resistance (AMR), particularly in resource-limited regions, posing a critical threat to global public health. Current antibiotic susceptibility test (AST) technologies are ...
Intrinsic N-Terminal Reactivity and Improved Analysis of DSSO-Carbamate and Carbamate-Based Cross-Linkers [0.03%]
基于DSSO缩氨脲和缩氨脲交联剂的内在N末端反应性及其改进分析方法研究
Alessio Di Ianni,Thomas Fabian Leischner,Bogdan-Razvan Brutiu et al.
Alessio Di Ianni et al.
Cross-linking mass spectrometry (XL-MS) has emerged as a powerful approach for probing protein structure and conformational dynamics. Conventional cross-linkers typically contain two N-hydroxysuccinimide (NHS) ester groups that primarily ta...
Label-Free Imaging and Refractive Index Mapping of Biological Tissues by Hyperspectral SPR Microscopy [0.03%]
基于超光谱SPR显微镜的生物组织无标记成像及折射率映射技术
Bo Yang,Hongyi Tang,Zhi-Mei Qi
Bo Yang
Staining of tissue sections and subsequent microscopic imaging are two key steps in conducting conventional histopathological analysis, but these processes are complex and time-consuming, and the image analysis results largely depend on the...
A BBB-on-a-Chip for Ischemic Stroke Modeling: In Situ Multiparameter Monitoring with Integrated TEER and Ion Sensors [0.03%]
集成TEER和离子传感器的缺血性卒中芯片模型的多参数监测研究
Yuanheng Kuang,Xiaoyu Wu,Feng Zhu et al.
Yuanheng Kuang et al.
Ischemic stroke is a leading cause of death and disability worldwide, resulting in blood-brain barrier (BBB) disruption and ionic homeostasis imbalance. However, existing models lack the ability to simultaneously monitor BBB integrity and i...
A Multivalent Aptamer-Driven "4 + 1" Nanozyme Platform for Ultrasensitive Detection and Synergistic Inactivation of Salmonella typhimurium [0.03%]
一种用于检测和协同灭活鼠伤寒沙门氏菌的超灵敏四配体适配子驱动的“4 + 1”型纳米酶平台
Qing Kang,Yidi Liu,Xiubing Cui et al.
Qing Kang et al.
Herein, we developed a novel "4 + 1" biosensing platform based on cascaded nucleic acid amplification and nanozyme activity, enabling fluorescence-colorimetric dual-mode detection and efficient inactivation of Salmonella Typhimurium (S. typ...
A Universal Near-Zero-Background Biosensing Platform: Engineered p-MXene/Quantum Dot@Aptamer Nanocomposites for Ultrasensitive Molecular Detection [0.03%]
一种通用型近零背景生物传感平台：工程化p型MXene/量子点@适配体纳米复合材料实现超灵敏分子检测
Chun Yang,Zunquan Zhao,Qichen Yang et al.
Chun Yang et al.
MXene-based fluorescent aptasensors detect targets through MXene-mediated adsorption of labeled aptamer probes and subsequent target-induced release of the probe signals, providing a promising programmable detection approach. However, their...
Covalent Organic Frameworks: A Novel Class of Metal-Free Catalysts for Efficient Photochemical Vapor Generation [0.03%]
用于高效光化学蒸汽生成的金属有机框架类无金属催化剂
Tong Zhang,Ji Yang,Shen Long et al.
Tong Zhang et al.
Photochemical vapor generation (PVG) is an attractive yet under-exploited sample-introduction strategy for atomic spectrometry. There remain challenges in improving the efficiency of PVG of elements and expanding the range of PVG applicatio...