David B Amabilino,Nina D Berova,John Caldwell
David B Amabilino
Editorial
Chirality. 2016 Dec;28(12):769-770. DOI:10.1002/chir.22666 2016
Molecules-in-molecules fragment-based method for the calculation of chiroptical spectra of large molecules: Vibrational circular dichroism and Raman optical activity spectra of alanine polypeptides [0.03%]
基于分子内分子片段的计算手性光谱方法：甘氨酸多肽的振动圆二色和拉曼光学活性光谱
K V Jovan Jose,Krishnan Raghavachari
K V Jovan Jose
The molecules-in-molecules (MIM) fragment-based method has recently been adapted to evaluate the chiroptical (vibrational circular dichroism [VCD] and Raman optical activity [ROA]) spectra of large molecules such as peptides. In the MIM-VCD...
Solid-phase extraction with metal-organic frameworks for the analysis of chiral compounds [0.03%]
基于金属有机骨架的固相萃取的手性化合物分析研究进展
Bo Tang,Jun-Hui Zhang,Min Zi et al.
Bo Tang et al.
Metal-organic frameworks (MOFs) are excellent porous materials with nanoscale cavities and high surface areas, which make them promising as novel adsorbents in solid-phase extraction (SPE). In this article we report a new application of the...
High-performance liquid chromatography evaluation of the enantiomeric purity of amino acids by means of automated precolumn derivatization with ortho-phthalaldehyde and chiral thiols [0.03%]
高效液相色谱法评价氨基酸的手性纯度：邻苯二醛与手性硫醇自动预衍生化法
Raphael Kühnreich,Ulrike Holzgrabe
Raphael Kühnreich
The use of ortho-phthalaldehyde (OPA) for the derivatization of amino acids (AA) is well known. It enables the separation of the derivatives on common reversed phase columns and improves the sensitivity with fluorescence detection. With the...
Heng Yue,Song Fang,Yizhi Zhang et al.
Heng Yue et al.
The enantioselective effects of the chiral pesticide metalaxyl on soil enzyme activity were investigated. Incubation experiments were conducted to investigate the effects of metalaxyl enantiomers at different concentrations on the activitie...
Effects of solvent on inclusion complexation of a chiral dipeptide toward racemic BINOL [0.03%]
溶剂对开链双肽与对映纯联萘酚包合物作用的影响
Xiaoyun Hu,Yuyuan Yang,Shuai Shi et al.
Xiaoyun Hu et al.
The effects of reaction solvent on inclusion complexation of a chiral dipeptide (3S,6S)-1 derived from (S)-proline toward racemic BINOL was investigated, discovering that the reaction solvent played a crucial role in determining the inclusi...
Claisen-Schmidt condensation: Synthesis of (1S,6R)/(1R,6S)-2-oxo-N,4,6-triarylcyclohex-3-enecarboxamide derivatives with different substituents in H2 O/EtOH [0.03%]
Claisen-Schmidt缩合：水/乙醇中不同取代基的(1S,6R)/(1R,6S)-2-氧化-N，4，6-三芳基环己-3-烯甲酰胺衍生物的合成
Seyyed Rasul Mousavi
Seyyed Rasul Mousavi
A simple, green, and direct three-component condensation of acetophenone, aromatic aldehydes with 3-oxo-N-phenylbutanamide (acetoacetanilide) to generate some novel (1S,6R)/(1R,6S)-2-oxo-N,4,6-triarylcyclohex-3-enecarboxamide derivatives wa...
Analysis of flumequine enantiomers in rat plasma by UFLC-ESI-MS/MS [0.03%]
高效液相色谱-串联质谱手性分析恩诺沙星对映体在大鼠血浆中的代谢动力学研究
Zhao-Hong Hu,Yang-Guang Wang,Huo-Xi Jin et al.
Zhao-Hong Hu et al.
In this study the analysis and confirmation of flumequine enantiomers in rat plasma by ultra-fast liquid chromatography coupled with electron spray ionization mass spectrometry (using propranolol as an internal standard [IS]) was developed ...
Highly enantioselective Michael addition of cyclohexanone to nitroolefins catalyzed by pyrrolidine-based bifunctional benzoylthiourea in water [0.03%]
脯氨酰硫脲催化的水相Michael加成反应构筑手性γ-内酯分子
Zhen-Yu Wang,Shu-Rong Ban,Meng-Chen Yang et al.
Zhen-Yu Wang et al.
Organocatalysis and aqueous reactions are identified as the focus of the greening of chemistry. Combining these two strategies effectively remains an interesting challenge in organic synthesis. Herein, we used pyrrolidine-based benzoylthiou...
A stereodynamic phosphoramidite ligand derived from 3,3'-functionalized ortho-biphenol and its rhodium(I) complex [0.03%]
一种来源于3,3'-官能团化联苯二酚的动态立体化学膦酰胺配体及其铑(I)配合物
Golo Storch,Luisa Deberle,Jan-Michael Menke et al.
Golo Storch et al.
Stereodynamic ligands and complexes bearing functional groups to attach chiral or achiral binding sites and auxiliaries are highly attractive due to the interesting opportunities for controlling the stereochemical outcome of enantioselectiv...