An efficient and enantioselective Michael addition of aromatic oximes to α,β-unsaturated aldehydes promoted by a chiral diamine catalyst derived from α,α-diphenyl prolinol [0.03%]
脯氨酸衍生物手性二胺催化剂对芳香肟与α，β-不饱和醛的迈克尔加成反应的研究
Feng Chen,Hong-Xia Ren,Yu Yang et al.
Feng Chen et al.
Chiral diamine catalysts 11a-e derived from α,α-diphenyl prolinol were prepared and successfully applied to the Michael addition of aromatic oximes to α,β-unsaturated aldehydes in mediocre to good yields (up to 78%) and good to high ena...
Preparative chiral separation and absolute configuration of the synthetic pterocarpanquinone LQB-118 [0.03%]
合成含羟基香豆素结构的pterocarpanquinone LQB-118的 preparative 色谱拆分及其绝对构型确定
Gabriel S Scatena,Neila M Cassiano,Chaquip D Netto et al.
Gabriel S Scatena et al.
The racemic pterocarpanquinone LQB-118 is active, in mice and hamsters, against tegumentary and visceral leishmaniasis. This compound also presents antiinflammatory and antineoplastic activity in mice. The low level of toxicity observed in ...
Highly enantioselective asymmetric direct aldol reaction promoted by aziridine amides constructed on chiral terpene scaffold [0.03%]
由手性单萜骨架构建的氮杂环丁烷酰胺促进的高度对映选择性不对称直接aldol反应
Zuzanna Wujkowska,Aleksandra Strojewska,Adam M Pieczonka et al.
Zuzanna Wujkowska et al.
Optically pure, diastereomeric aziridine amides built on the chiral skeletons of camphor, fenchone, and menthone have proven to be highly efficient ligands for enantioselective asymmetric direct aldol reaction in the presence of water and z...
Chiral analysis of ammuxetine enantiomers in dog plasma using online SPE/liquid chromatography with tandem mass spectrometric detection after precolumn chiral derivatization [0.03%]
手性衍生前柱手性分离高效液相色谱-串联质谱法测定犬血浆中的安非他酮对映异构体
Jimei Yu,Xin Li,Jiezhao Zhou et al.
Jimei Yu et al.
Ammuxetine (AMT), a novel chiral antidepressant candidate compound, exhibits better antidepression effects than duloxetine in different animal models. In this article, a chiral derivatization method, combined with online solid phase extract...
CDSpecTech: A single software suite for multiple chiroptical spectroscopic analyses [0.03%]
CDSpectech：一种用于多种旋光光谱分析的单一软件套件
Cody L Covington,Prasad L Polavarapu
Cody L Covington
The program CDSpecTech was developed to facilitate the analysis of chiroptical spectra, which include the following: vibrational circular dichroism (VCD) and corresponding vibrational absorption (VA) spectra; vibrational Raman optical activ...
Enantiomeric NMR signal separation behavior and mechanism of samarium(III) and neodymium(III) complexes with (S,S)-ethylenediamine-N,N'-disuccinate [0.03%]
含(S,S)-乙二胺-N，N'-双琥珀酸配体的Sm(III)和Nd(III)配合物拆分及机制的NMR谱学研究
Sen-Ichi Aizawa,Masaru Okano,Takahiro Kidani
Sen-Ichi Aizawa
Enantiomeric 1 H and 13 C NMR signal separation behaviors of various α-amino acids and DL-tartarate were investigated by using the samarium(III) and neodymium(III) complexes with (S,S)-ethylenediamine-N,N'-disuccinate as chiral shift reage...
Anvar S Baimuratov,Nikita V Tepliakov,Yurii K Gun&#x;Ko et al.
Anvar S Baimuratov et al.
Here we review our three recently developed analytical models describing the intraband optical activity of semiconductor nanocrystals, which is induced by screw dislocations, ionic impurities, or irregularities of the nanocrystal surface. T...
Emma Evertsson,Julia Rönnberg,Jonna Stålring et al.
Emma Evertsson et al.
The screening of a number of chiral stationary phases (CSPs) with different modifiers in supercritical fluid chromatography to find a chromatographic method for separation of enantiomers can be time-consuming. Computational methods for data...
A chiral, porous, organic cage-based, enantioselective potentiometric sensor for 2-aminobutanol [0.03%]
用于手性识别的基于手性有机笼的enantioselective电位传感器₂-氨基丁醇
Ai-Hong Duan,Bang-Jin Wang,Sheng-Ming Xie et al.
Ai-Hong Duan et al.
A new enantioselective potentiometric sensor containing R-type chiral porous organic cage CC9 as the chiral selector was designed for the assay of 2-aminobutanol. Optimized membrane electrodes displayed a linear dynamic range from 10-3 ~ 10...
Thermal effects in guest-host systems: [Zn2 (bdc)(S-lac)(dmf)]•PhEtOH: A DSC and NMR study [0.03%]
主客体体系中的热效应：[Zn₂(bdc)(S-lac)(dmf)]·PhEtOH（DSC和NMR研究）
Svetlana G Kozlova,Denis P Pishchur,Marsel R Gallyamov
Svetlana G Kozlova
Differential scanning calorimetry and nuclear magnetic resonance were used to investigate thermal effects in the guest-host systems where homochiral metal-organic sorbent [Zn2 (bdc)(S-lac)(dmf)] is considered as a host while 1-phenylethanol...