Cocrystals of telmisartan with ascorbic acid: Enhanced solubility and antiviral potency against Japanese encephalitis virus [0.03%]
依托考昔与抗坏血酸共晶：对日本脑炎病毒的增强溶解度和抗病毒功效
Varaprasad Rao Regu,Ankita Datey,Tompe Krishna Vitthal et al.
Varaprasad Rao Regu et al.
The significant impact of Japanese encephalitis virus (JEV) on society and the lack of any approved antiviral drugs demand urgent attention. Considering the prohibitive cost involved in new antiviral development, repurposing existing drugs ...
Silicone-oil migration in prefilled syringes induces smoke-like particulates in ultra-high viscosity formulations [0.03%]
预填充注射器中硅油的迁移会导致超高粘度配方产生烟雾状颗粒物
Yunjiao Chi,Xingchun Jiang,Jun Li et al.
Yunjiao Chi et al.
Visible smoke-like particles are occasionally observed in ultra-high viscosity (UHV) formulations, such as ophthalmic viscosurgical devices (OVDs), stored in prefilled syringes (PFS), leading to reduced product yield. In this study, spatial...
Mechanistic dermal patch modelling for fentanyl: Linking in vitro release and permeation data to a physiologically based pharmacokinetic approach [0.03%]
基于生理的药代动力学方法联系体外释放和渗透数据进行芬太尼透皮贴剂建模研究
Daniel Paterson,Yanling Zhang,Sebastian Polak et al.
Daniel Paterson et al.
Dermal physiologically based pharmacokinetic (PBPK) models can be informed by various types of data. In vitro permeation testing (IVPT) experiments aid parameterisation of skin permeation independent of the complexities of systemic uptake. ...
Rule-based mitigation of charge asymmetry-triggered monoclonal antibody self-assembly [0.03%]
基于规则的缓解电荷不对称引起的单克隆抗体自组装
Inna Brakti,Anette Henriksen,Maria Łucja Tomczak et al.
Inna Brakti et al.
When evaluating the proclivity of a monoclonal antibody (mAb) for non-specific self-assembly, it is common to restrict charge distribution analyses to the variable region of mAbs, leaving out possible contributions from the constant region ...
Corrigendum Engineering of Layer-By-Layer Acetate Coated Paclitaxel Loaded Poly(lactide-Co-Glycolide Acid Nanoparticles for Prostate Cancer Therapy- In Vitro Journal of Pharmaceutical Sciences Volume 113, Issue 11, November 2024, Pages 3375-3383 [0.03%]
用于前列腺癌治疗的分层醋酸涂层载 paclitaxel 聚(l-乳酸-co-glycolide)纳米颗粒的工程化-体外研究（《药物科学杂志》第113卷，第11期，2024年11月，页码3375-3383 的更正）
Albert Nguessan Ngo,Kierston K Chatman,Dezirae Douglas et al.
Albert Nguessan Ngo et al.
Published Erratum
Journal of pharmaceutical sciences. 2026 Feb 19:104216. DOI:10.1016/j.xphs.2026.104216 2026
Development of an active loading strategy for methylene blue in liposomes and its application in EGFR-targeted photodynamic therapy [0.03%]
用于脂质体的亚甲蓝主动加载策略的发展及其在EGFR靶向光动力治疗中的应用
Guozi Xia,Rui Cao,Lizhen Huang et al.
Guozi Xia et al.
As an ancient drug, methylene blue (MB) has shown promise in tumor photodynamic therapy (PDT) due to its excellent light-induced reactive oxygen species (ROS) yield. However, its rapid plasma clearance and lack of tumor targeting have limit...
Navigating the complexities in characterization of NDSRIs using advanced analytical techniques [0.03%]
利用先进分析技术剖析NDSRI的复杂性
Koushik Mondal,Veera Reddy,Suresh Kumar Sk et al.
Koushik Mondal et al.
The accurate detection and quantification of nitrosamine drug substance related impurities (NDSRIs) requires validated analytical techniques. However, the availability of standards for validation is still evolving due to the structural comp...
Determination of naloxone and its impurities in a vaporized matrix by LC-MS/MS: Application of an in vitro surrogate model platform to assess in vivo permeation and risk associated with vaping opioids [0.03%]
液相色谱-质谱联用测定纳络酮及其杂质：体外替代模型平台评估吸入式阿片类药物渗透及风险的应用
Dustin G Brown,Tasmin Ara Sultana,Patrick Faustino et al.
Dustin G Brown et al.
E-cigarette use in the U.S. has risen over the past decade, particularly among youth and young adults, prompting potential public health concerns. In response, public health agencies including the FDA have initiated studies to assess associ...
Preparation of novel in situ film-forming gel impregnated with clotrimazole-loaded liquid crystalline nanoparticles: In vitro, ex vivo, in vivo dermatopharmacokinetic and antifungal evaluation [0.03%]
载有克霉唑负载型液晶纳米粒的新型就位成膜凝胶的制备及体外、离体及抗真菌评价
Radhika Sharma,Gautam Singhvi,Vikas Rana
Radhika Sharma
In an attempt to conquer the significant concerns, viz. patient discomfort due to repeated application, low skin permeability, retention, and low therapeutic efficacy of conventional topical formulations (creams, ointments, etc.) for the ma...
Corrigendum to Mechanistic Insights into Drug Loading Effect on Dissolution Performance of Loratadine-Soluplus® Amorphous Solid Dispersions [0.03%]
洛拉替丁-索鲁普鲁斯均质固态分散体的药物载药量效应对溶解性能影响的机制研究校正意见
Jannat Falah Hassan,Kawther Khalid Ahmed,Tze Ning Hiew
Jannat Falah Hassan
Published Erratum
Journal of pharmaceutical sciences. 2026 Feb 16:104211. DOI:10.1016/j.xphs.2026.104211 2026