Intranasal delivery of metal/metal oxide nanoparticles for the management of CNS-related diseases: Theranostic and toxicity issues [0.03%]
金属/金属氧化物纳米颗粒的鼻内递送在中枢神经系统相关疾病管理中的治疗诊断学和毒性问题
Samin Hamidi,Zahra Esmaeili Moghaddam,Mitra Alami-Milani et al.
Samin Hamidi et al.
ObjectiveThe main objective of this article was to explore the therapeutic potential of intranasally administered metal/metal oxide nanoparticles (NPs) for treating central nervous system (CNS) disorders.Significance of reviewMetal/metal ox...
Advancing transdermal drug delivery systems: breakthrough innovations, comprehensive evaluation approaches for optimized therapeutic efficacy and patient outcomes [0.03%]
经皮给药系统研究进展:面向高效治疗和患者获益的创新突破及综合评价方法
Soji Soman,Priyanka Venkatesan,P N Remya
Soji Soman
Objective: To provide a comprehensive overview of recent advancements in transdermal drug delivery systems (TDDSs), with a focus on their design, development, evaluation, and therapeutic importance. ...
Cyclodextrin-Based Inclusion Complexes to Enhance the Solubility and Oral Bioavailability of Indapamide: Experimental and Computational Approaches [0.03%]
用于增强吲达帕胺溶解度和口服生物利用度的 cyclodextrin 包合物:实验与计算方法
Khaldoun A Al-Souod,Gaith M Al-Qudah,Rajab Abu-El-Halawa
Khaldoun A Al-Souod
Objective: Indapamide, a thiazide-like diuretic, exhibits very low aqueous solubility, which restricts its oral bioavailability and therapeutic efficacy. This study aimed to enhance its solubility and stability by forming...
Overcoming Bottlenecks in Drug Delivery: The Promise of Biomolecular and Artificial Molecular Motors [0.03%]
克服药物输送瓶颈:生物分子和人造分子马达的前景
Jingling Wang,Zhao Jinhong,Zhang Haoyu et al.
Jingling Wang et al.
ObjectiveMolecular motors are nanoscale devices capable of converting chemical, light, or magnetic energy into mechanical motion. This review aims to provide a comprehensive overview of recent advancements in molecular motor technology, wit...
Onosma mutabilis- Mediated Silver Nanoparticles Target Lung Cancer Cell Viability and Migration: In Vitro Evidence from A549 Model [0.03%]
基于Onosma mutabilis的银纳米颗粒对肺癌A549细胞活性和迁移的影响:体外证据
Pelin Eroglu,Selda Doğan Çalhan,Hamide Doğan
Pelin Eroglu
ObjectiveSilver nanoparticles (AgNPs) are widely utilized in anti-migratory applications due to their beneficial physicochemical and biological properties. This study aimed to evaluate the in vitro cytotoxic and anti-migratory effects of Ag...
Unveiling the mechanistic aspect of biogenic copper oxide nanoparticles harnessing Citrus pseudolimon for eradicating multi-drug-resistant gram-negative bacilli [0.03%]
利用柑橘属假柠檬生物法生成铜氧化学纳米颗粒以根除多重耐药革兰氏阴性杆菌的机制研究
Shahbaz Aman,Divya Mittal,Narinder Kaur et al.
Shahbaz Aman et al.
Objective: Bacterial infections caused by multidrug-resistant (MDR) strains pose a serious global health threat. This study aimed to evaluate the antibacterial efficacy of green-synthesized copper nanoparticles (G-CuNPs) ...
Lyophilization Process Design and Development of Human Plasma Derived Alpha 1 Proteinase Inhibitor [0.03%]
人血浆源性α1蛋白酶抑制剂冻干工艺设计及开发研究
Sumita Bardhan,Dhruv Parikh,Sheetal Dolia et al.
Sumita Bardhan et al.
Lyophilization is the preferred method to stabilize labile protein formulations in order to attain longer shelf life. Thus, the understanding of different parameters of lyophilization along with inherent properties of plasma protein formula...
Correction [0.03%]
改正
Published Erratum
Drug development and industrial pharmacy. 2025 Dec 1:1. DOI:10.1080/03639045.2025.2594847 2025
Ionically cross-linked pH-responsive interpenetrating polysaccharide network hydrogel tablets for colon-targeted delivery of budesonide [0.03%]
用于结肠定位递送布地奈德的离子交联pH响应型互穿多糖网络凝胶片剂
Pallobi Dutta,Kaushik Mukherjee,Tapan Kumar Giri
Pallobi Dutta
Objective: To develop ionically cross-linked pH-responsive interpenetrating polysaccharide network hydrogel tablets for the colon-targeted delivery of budesonide (BUD). ...
Oridonin-loaded liposomes targeting lung cancer: formulation and delivery in vitro and in vivo [0.03%]
荷载oral啶的肺癌靶向脂质体:体内外递送及配方研究
Cheng Shi,Libin Zhang,Ping Hu
Cheng Shi
Purpose: Oridonin (ORI) is an ent-kaurene tetracyclic diterpenoid with anti-tumor activities in various tumor cell lines. However, its hydrophobicity and non-targeting have greatly limited the clinical application of ORI....