Development and evaluation of a multifunctional natural composite microemulsion for anti-acne therapy: synergistic anti-inflammatory and antibacterial effects [0.03%]
Siqi Rao,Ying Chen,Chunlin Tao et al.
Siqi Rao et al.
Introduction: Acne is a common inflammatory disease of the hair follicles and sebaceous glands, but most of the current treatments have side effects or drug resistance problems. This study developed a stable, self-emulsif...
Enhancing dissolution of poorly water-soluble prednisolone via spray-dried arabinoxylan microspheres: a novel arabinoxylan-based drug delivery system [0.03%]
Muniyandy Saravanan,Rowena Gan,Chin Jia Rei et al.
Muniyandy Saravanan et al.
Background: Prednisolone's poor aqueous solubility limits its oral bioavailability, necessitating the development of innovative formulation strategies. Ob...
Formulation and Optimization of Dryopteris cochleata extract-laden liposomes for immunostimulant activity in rats: In vitro and in vivo evaluation [0.03%]
Shubhangi Patil,Popat Kumbhar,Rajnandini Patil et al.
Shubhangi Patil et al.
Objective: The current study sought to develop Dryopteris cochleata (DC) extract encapsulated liposomes and their characterization in order to increase its immunomodulatory activity. ...
Systematic review on effectiveness of flavonoids against breast cancer: insights from in-vitro, in-vivo studies and molecular pathway studies [0.03%]
黄酮类化合物抗乳腺癌作用的系统评价：基于体外、体内研究及分子途径研究的见解
Deepika Sharma,Malakapogu Ravindra Babu,Shriyansh Srivastava
Deepika Sharma
Objective: On a global scale, breast cancer is the most prevalent form of cancer that affects women and the leading cause of death. Radiation therapy, chemotherapy, and hormone therapy are the contemporary approaches that...
Injectable grafts for hard tissue engineering: current trends and future perspectives [0.03%]
用于硬组织工程的注射型移植物：现状和未来展望
Rajeev Ranjan,Vikash Kumar,Ayush Katyayan
Rajeev Ranjan
Objective: Injectable bone grafts have emerged as a promising solution for bone tissue regeneration due to their minimally invasive nature and ability to conform to complex anatomical defects. Recent advancements in mater...
Intranasal Nanoemulsion-based In-Situ Gel Containing Dexlansoprazole: Formulation Development, In-Vitro and Ex-Vivo Evaluation [0.03%]
含有DEXLANSOPRAZOLE的鼻用纳米乳原位凝胶制剂的研发及体外和在体评价
Gyati Shilakari,U Sai Kumar,Meghamala G et al.
Gyati Shilakari et al.
Aim: Dexlansoprazole (DXL) is clinically effective in gastroesophageal reflux and ulcer healing, yet its oral bioavailability is compromised by acid instability, poor aqueous solubility, and extensive first-pass metabolis...
Estimation of rezdiffra (MGL-3196) by validated RP-HPLC approach in bulk material and pharmaceutical formulation [0.03%]
一种经验证的RP-HPLC方法在原料和制剂中估算Rezdiffra（MGL-3196）含量
Md Abid Hasan,Raisa Tasnim,Ejaj Sumit et al.
Md Abid Hasan et al.
Introduction: Rezdiffra MGL-3196 is a newly authorized systemic medication for moderate to severe liver fibrosis associated with noncirrhotic nonalcoholic steatohepatitis (NASH). ...
Curcumin-loaded beta-glucan nanoparticles: preparation, physicochemical properties, and molecular modeling [0.03%]
姜黄素载荷β-葡聚糖纳米粒：制备、理化性质及分子模拟研究
Quoc-Hoai Nguyen,An-Khanh Pham,Huu-Manh Nguyen et al.
Quoc-Hoai Nguyen et al.
Objectives: This study introduces the application of wet milling, a well-established top-down technique, as a novel approach for preparing beta-glucan nanoparticles (BG-NPs) as carriers for poorly soluble drugs, using cur...
Enhanced topical delivery of terbinafine HCl nanomicelles embedded in chitosan gel for improved antifungal activity [0.03%]
壳聚糖凝胶中特比萘芬HCl纳米胶束制剂的经皮递送及其抗真菌作用增强效果的研究
Gul-E Maryam,Fazli Nasir,Shazma Gohar et al.
Gul-E Maryam et al.
Objectives: Terbinafine Hydrochloride nanomicelles loaded chitosan gel was prepared with a goal to provide effective and controlled drug deliveryto the skin layers where conventional topical preparations are unable to pen...
AQbD-based UHPLC approach for quantification of everolimus residues in cleaning validation processes [0.03%]
基于AQbD的UHPLC法在抗肿瘤药物西罗莫司清洁验证过程残留量测定中的应用研究
Jagdish Gohel,Ajay Patel,Rajendra Kotadiya
Jagdish Gohel
Objective: This study aimed to develop and validate a robust reverse-phase ultra-performance liquid chromatography (UHPLC) method for the quantification of everolimus residues on pharmaceutical manufacturing equipment sur...