Orodispersible Tablets in Psychiatric and Mood Disorder Management: Clinical Value, Pharmacokinetics, and Patient-Centric Formulation Strategies [0.03%]
Psychiatry和情绪障碍管理中的可分散口腔速崩片:临床价值、药动学及以患者为中心的制剂策略
Govind Kumar,Ishu Garg,Rohit Raj et al.
Govind Kumar et al.
Objective: To analyse the extensive literature underlying the concept of using and formulating Orodispersible tablets (ODTs) for managing psychiatric and mood disorders. ...
"Extraction, Development, and Ex-Vivo Evaluation of Thermoresponsive Mucoadhesive In-Situ Nasal Gel Incorporating Lablab purpureus Mucilage and Pluronic F127 for Enhanced Intranasal Delivery of Diclofenac Sodium" [0.03%]
“含刀豆属凝胶和Pluronic F127的温度响应性鼻粘膜给药凝胶剂的提取、开发及体外评价用于增强硫酸氨基葡萄糖的鼻内递送”
Adarsha Bachhar,Amitava Roy,Sanchita Mandal
Adarsha Bachhar
Objective: This study aimed to develop and evaluate a thermoresponsive, mucoadhesive in-situ nasal gel using Lablab purpureus mucilage and Pluronic F127 for intranasal delivery of Diclofenac Sodium to enhance bioavailabil...
A Review on Artificial Intelligence in Pharmaceutical Sciences: Opportunities & Challenges [0.03%]
人工智能在药学科学中的机遇与挑战综述
Vivek Kumar,Saurav Kumar,Ravi Kumar et al.
Vivek Kumar et al.
SignificanceThe review aims to systematically explore the transformative impact of artificial intelligence (AI) on pharmaceutical sciences. It Address key research questions regarding how AI accelerates drug development, enhances clinical t...
Pregabalin-loaded transferosomal gel for enhanced topical delivery in peripheral neuropathy: formulation, in vitro and ex vivo evaluation [0.03%]
布加比林载药转移体凝胶促进外周神经病的透皮递送:处方、体外及组织实验评估
Mariya Sanjana A,Ashvini H M
Mariya Sanjana A
Objective: To formulate and evaluate a pregabalin-loaded transferosomal gel for transdermal delivery aimed at, improving skin penetration, sustaining drug release, and increasing patient compliance in the management of pe...
Polyherbal green-synthesised silver nanoparticle gel: in vitro antimicrobial activity and in vivo wound healing efficacy using mimosa pudica and tribulus terrestris extracts [0.03%]
用含 Mimosa Pudica 和 Tribulus Terrestris 提取物的聚草本绿色合成银纳米颗粒凝胶进行体外抗菌活性及体内促伤口愈合功效研究
Purushotham C M,Mallamma T,Parimala Hanumesh et al.
Purushotham C M et al.
Objective: To synthesize and evaluate a polyherbal silver nanoparticle (PH-AgNPs) gel using Mimosa pudica and Tribulus terrestris extracts for enhanced antimicrobial activity and wound-healing efficacy. ...
Improvement of aqueous solubility and oral bioavailability of luteolin: a nanosuspension approach [0.03%]
纳米悬浮液技术改善芹菜素的水溶性和口服生物利用度
Hari Priya Sripadi,Sai Balaji Andugulapati,Vijaya Sarathi U V R et al.
Hari Priya Sripadi et al.
Objective: Luteolin (LT), a naturally occurring flavonoid and biopharmaceutical classification system (BCS) Class II compound, holds broad pharmacological potential. However, its clinical application is limited by poor wa...
Development and evaluation of a multifunctional natural composite microemulsion for anti-acne therapy: synergistic anti-inflammatory and antibacterial effects [0.03%]
一种多功能天然复合微乳液的开发与评价:协同抗炎抗菌功效用于治痘疗法的研究与发展评估
Siqi Rao,Ying Chen,Chunlin Tao et al.
Siqi Rao et al.
Introduction: Acne is a common inflammatory disease of the hair follicles and sebaceous glands, but most of the current treatments have side effects or drug resistance problems. This study developed a stable, self-emulsif...
Enhancing dissolution of poorly water-soluble prednisolone via spray-dried arabinoxylan microspheres: a novel arabinoxylan-based drug delivery system [0.03%]
通过喷雾干燥阿拉伯木聚糖微球增强难溶性药物prednisolone的溶解度:一种新型的阿拉伯木聚糖为基础的药物递送系统
Muniyandy Saravanan,Rowena Gan,Chin Jia Rei et al.
Muniyandy Saravanan et al.
Background: Prednisolone's poor aqueous solubility limits its oral bioavailability, necessitating the development of innovative formulation strategies. Ob...
Formulation and Optimization of Dryopteris cochleata extract-laden liposomes for immunostimulant activity in rats: In vitro and in vivo evaluation [0.03%]
基于干寡鳞鳞毛蕨提取物免疫佐剂作用机制的脂质体递送系统制备及优化研究
Shubhangi Patil,Popat Kumbhar,Rajnandini Patil et al.
Shubhangi Patil et al.
Objective: The current study sought to develop Dryopteris cochleata (DC) extract encapsulated liposomes and their characterization in order to increase its immunomodulatory activity. ...
Systematic review on effectiveness of flavonoids against breast cancer: insights from in-vitro, in-vivo studies and molecular pathway studies [0.03%]
黄酮类化合物抗乳腺癌作用的系统评价:基于体外、体内研究及分子途径研究的见解
Deepika Sharma,Malakapogu Ravindra Babu,Shriyansh Srivastava
Deepika Sharma
Objective: On a global scale, breast cancer is the most prevalent form of cancer that affects women and the leading cause of death. Radiation therapy, chemotherapy, and hormone therapy are the contemporary approaches that...