Pan Tian,Fan Yang,Li-Ping Yu et al.
Pan Tian et al.
The aim of this study was to determine the effect of varying excipient content on the formation and physical properties of 3 D printed tablets. Fifteen different excipient preparations were formed into tablets with radii of 5 mm and thickne...
Natamycin niosomes as a promising ocular nanosized delivery system with ketorolac tromethamine for dual effects for treatment of candida rabbit keratitis; in vitro/in vivo and histopathological studies [0.03%]
一种新的眼部递送系统：载那他霉素和酮咯酸氨丁三醇硝酸纳滴眼液治疗兔子白色念珠菌性角膜炎的体内外及组织病理研究
Mohamed Ahmed El-Nabarawi,Randa Tag Abd El Rehem,Mahmoud Teaima et al.
Mohamed Ahmed El-Nabarawi et al.
Objectives: This study was aimed to develop dual-purpose natamycin (NAT)-loaded niosomes in ketorolac tromethamine (KT) gels topical ocular drug delivery system to improve the clinical efficacy of natamycin through enhanc...
One-step synthesis of phyto-polymer coated gold nanospheres as a delivery system to enhance resveratrol cytotoxicity [0.03%]
一步合成植物聚合物涂层金纳米球作为递送系统以增强白藜芦醇细胞毒性
Maha Fadel,Kawser Kassab,Tareq Youssef et al.
Maha Fadel et al.
This study introduces a simple method for one-step synthesis of highly stable nontoxic polymer-coated gold nanospheres for use in drug delivery, focuses on the ability of chloroauric acid (HAu Cl4 ) to induce polyphenols polymerization, put...
Metronidazole-loaded nanostructured lipid carriers to improve skin deposition and retention in the treatment of rosacea [0.03%]
用于治疗玫瑰痤疮的甲硝唑纳米结构脂质载体以改善皮肤沉积和保留
Ujwala A Shinde,Shruti J Parmar,Shuba Easwaran
Ujwala A Shinde
The objective of the present investigation was to improve the skin deposition and retention of metronidazole (MTZ) in rosacea therapy by incorporating it into nanostructured lipid carriers (NLCs). The main challenge in this endeavor was the...
Chrysin-loaded folate conjugated PF127-F68 mixed micelles with enhanced oral bioavailability and anticancer activity against human breast cancer cells [0.03%]
一种载染料木素的叶酸修饰的PF127-F68混合胶束及其口服抗乳腺癌活性研究
Debjani Baidya,Jeetendra Kushwaha,Kakasaheb Mahadik et al.
Debjani Baidya et al.
Chrysin (CH), a phytoconstituent has numerous pharmacological activities including anticancer activity. However, CH suffers from a drawback of poor aqueous solubility and in turn poor bioavailability limiting its clinical utility. In this w...
Comparison of two paddle wheel geometries within the filling chamber of a rotary tablet press feed frame with regard to the distribution behavior of a model powder and the influence on the resulting tablet mass [0.03%]
比较旋转压片机进料框架填充室内的两种浆叶几何形状，以模化粉体的分布行为以及对所得药片质量的影响方面的情况
Kym Patrick Dühlmeyer,Hüseyin Özcoban,Claudia S Leopold
Kym Patrick Dühlmeyer
Objective: The purpose of this study was to compare the influence of two different paddle wheel geometries on the distribution behavior of a model powder within the filling chamber of the modified feed frame of a rotary tablet press. Moreov...
Co-processing of cefuroxime axetil by spray drying technique for improving compressibility and flow property [0.03%]
采用喷雾干燥技术对头孢呋辛酯进行共处理以改善其可压性和流动性
Punit Rathod,Dhaval Mori,Ramesh Parmar et al.
Punit Rathod et al.
The aim of the present investigation was to improve the compressibility and flow property of cefuroxime axetil by co-processing it with mannitol and chitosan chlorhydrate using spray drying method. 32 full factorial design, having inlet air...
Some observations on the liquid crystalline and gel behaviors of aqueous dispersions of a prodrug [0.03%]
关于前药水分散体系的液晶和凝胶行为的一些观察
Li Tao,Jinjiang Li,Swathi Pinamanenni et al.
Li Tao et al.
BMS-830216 is a diprotic acid prodrug of two pKa values (
Development and in vitro/in vivo evaluation of dihydroergotamine mesylate loaded maltodextrin-pullulan sublingual films [0.03%]
一种含有麦芽糊精-普鲁兰糖和麦角丁甲磺酸的舌下膜及其体内外评价研究论文
Ozgur Esim,Cansel K Ozkan,Sevinc Kurbanoglu et al.
Ozgur Esim et al.
Dihydroergotamine mesylate (DHE), ergotamine derivative, has been offered for clinical use to stop or treat symptoms of an emerging migraine as injection for more than a half century. It is shown that bioavailability of DHE greatly changes ...
Design by optimization and comparative evaluation of vesicular gels of etodolac for transdermal delivery [0.03%]
优化和比较评估用于经皮递送依托洛尔的囊泡凝胶体系的设计
Nimmathota Madhavi,Beeravelli Sudhakar,K V N Suresh Reddy et al.
Nimmathota Madhavi et al.
Aim of the present study was to design vesicular gels of etodolac loaded liposomes and ethosomes for effective transdermal delivery. The physicochemical properties of vesicular gels were compared with 45% v/v ethanolic etodolac solution and...