Brett A Helms
Brett A Helms
The mismanagement and leakage of plastic waste into the environment are failures of modern society. Once in the environment, plastic waste degrades into microplastics on a time scale dependent on the resin chemistry and the associated bioti...
Regio- and Diastereoselective Carbometalation Reaction of Cyclopropenes [0.03%]
环丙烯的区域和非对映选择性卡宾金属化反应
Yair Cohen,Ilan Marek
Yair Cohen
The various facets of the chemistry of cyclopropane derivatives, the smallest carbocycle, are amazingly diverse and continue to fascinate theoreticians, synthetic or structural chemists having interest in fundamental physical, medicinal che...
Vangelis Agouridas,Nathalie Ollivier,Jérôme Vicogne et al.
Vangelis Agouridas et al.
The last two decades have witnessed the rise in power of chemical protein synthesis to the point where it now constitutes an established corpus of synthetic methods efficiently complementing biological approaches. One factor explaining this...
Atropisomers with Axial and Point Chirality: Synthesis and Applications [0.03%]
轴手性和中心手性阿托罗异构体：合成与应用
Xing-Feng Bai,Yu-Ming Cui,Jian Cao et al.
Xing-Feng Bai et al.
Enantiopure atropisomers have become increasingly important in asymmetric synthesis and catalysis, pharmaceutical science, and material science since the discovery of inherent features of axial chirality originating from rotational restrict...
Enhancing Triplet-Triplet Annihilation Upconversion: From Molecular Design to Present Applications [0.03%]
从分子设计到当前应用的三重态-三重态湮灭上转换增强
Le Zeng,Ling Huang,Jinfeng Han et al.
Le Zeng et al.
Photon upconversion, the process of converting low-energy photons into high-energy ones, has been widely applied for solar energy conversion, photoredox catalysis, and various biological applications such as background-free bioimaging, canc...
Manganese Alkyl Carbonyl Complexes: From Iconic Stoichiometric Textbook Reactions to Catalytic Applications [0.03%]
锰烷基羰基配合物：从经典的计量反应教科书知识到催化应用研究
Stefan Weber,Karl Kirchner
Stefan Weber
The activation of weakly polarized bonds represents a challenging, yet highly valuable process. In this context, precious metal catalysts have been used as reliable compounds for the activation of rather inert bonds for the last several dec...
Real-Time Tracking of Electrical Signals and an Accurate Quantification of Chemical Signals with Long-Term Stability in the Live Brain [0.03%]
在活体大脑中实时追踪电信号并长期稳定地精确量化化学信号
Yuandong Liu,Zhichao Liu,Yang Tian
Yuandong Liu
The development of in vivo analytical tools and methods for recording electrical signals and accurately quantifying chemical signals is a key issue for a comprehensive understanding of brain events. The electrophysiological microelectrode w...
Mrityunjay Gupta,Samantha R Levine,Robert C Spitale
Mrityunjay Gupta
The discovery of previously unknown functional roles of RNA in biological systems has led to increased interest in revealing novel RNA molecules as therapeutic targets and the development of tools to better understand the role of RNA in cel...
Atropisomerism in Drug Discovery: A Medicinal Chemistry Perspective Inspired by Atropisomeric Class I PI3K Inhibitors [0.03%]
药物发现中的非对映异构现象——从联芳基化合物的非对映异构类PI3K抑制剂获得的药物化学观点
Stephane Perreault,Jayaraman Chandrasekhar,Leena Patel
Stephane Perreault
Atropisomerism is a type of axial chirality resulting from hindered rotation about a σ bond that gives rise to nonsuperimposable stereoisomers (termed "atropisomers"). The inversion of chirality of an atropisomeric axis is a time- and temp...
Steering Catalytic Selectivity with Atomically Dispersed Metal Electrocatalysts for Renewable Energy Conversion and Commodity Chemical Production [0.03%]
利用原子分散金属电催化剂调控催化选择性实现可再生能源转化及精细化工品生产
Jae Hyung Kim,Young Jin Sa,Taejung Lim et al.
Jae Hyung Kim et al.
Electrocatalysis is a key driver in promoting the paradigm shift from the current fossil-fuel-based hydrocarbon economy to a renewable-energy-driven hydrogen economy. The success of electrocatalysis hinges primarily on achieving high cataly...