N-Acylamino Acid Amidothiourea: A Versatile Chiral Helical Building Block [0.03%]
N-酰胺基氨基酸氨基硫脲：一种通用的手性螺旋构建单元
Qian Wang,Si-Yi Liu,Yun-Bao Jiang
Qian Wang
ConspectusThioureas represent an important class of molecular frameworks, distinguished by their hydrogen-bonding capabilities. This feature has enabled the development of a variety of synthetic anion receptors and advanced molecular techno...
Two-Dimensional Electrically Conductive Metal-Organic Frameworks: Insights and Guidelines from Theory [0.03%]
二维导电金属有机框架的理论见解与指导方针
Shogo Nakaza,Yuliang Shi,Zeyu Zhang et al.
Shogo Nakaza et al.
ConspectusTwo-dimensional (2D) metal-organic frameworks (MOFs) are a new class of multifunctional low-dimensional materials where extended layers of tetra-coordinated metal nodes with electron-rich π-conjugated organic linkers are stacked ...
Fei Nie,Dongpeng Yan
Fei Nie
ConspectusGlass is a vital material across diverse fields including photovoltaics, construction, medicine, telecommunications, and display technologies. Beyond conventional inorganic, metallic, and polymeric glasses, recent developments hav...
Annia Galano
Annia Galano
ConspectusWhat does the word antioxidant mean? Antioxidants are supposed to be nontoxic, versatile molecules capable of counteracting the damaging effects of oxidative stress (OS). Thus, when evaluating a candidate molecule as an antioxidan...
Hydroaminoalkylation: A Tool of Choice for the Catalytic Addition of Amines to Alkenes in Small Molecules and Materials [0.03%]
氢胺化反应：小分子和材料中催化胺加成到烯烃的工具首选反应
Saeed Ataie,Laurel L Schafer
Saeed Ataie
ConspectusHydroaminoalkylation, the catalytic addition of amines to alkenes, has evolved as a powerful tool in modern synthetic chemistry, offering an atom-economic and green approach to the construction of C-C bonds. This reaction enables ...
Quinoline as a Photochemical Toolbox: From Substrate to Catalyst and Beyond [0.03%]
喹啉作为光化学工具箱：从底物到催化剂及更广泛的用途
Jianbin Li,Chao-Jun Li
Jianbin Li
ConspectusMolecular photochemistry, by harnessing the excited states of organic molecules, provides a platform fundamentally distinct from thermochemistry for generating reactive open-shell or spin-active species under mild conditions. Amon...
Kazuki Shun,Kohsuke Mori
Kazuki Shun
ConspectusHydrogen spillover, the simultaneous diffusion of protons and electrons, has recently emerged as a key phenomenon in the functionalization of hydrogen in cutting-edge research fields. Its occurrence has been found to significantly...
Stabilization of Native Protein-Protein Interactions with Molecular Glues: A 14-3-3 Case Study [0.03%]
利用分子胶稳定天然蛋白质相互作用：以14-3-3为例
Markella Konstantinidou,Johanna M Virta,Michelle R Arkin
Markella Konstantinidou
ConspectusProtein-protein interactions (PPIs) play a key role in homeostasis and are often dysregulated in disease. PPIs were traditionally considered "undruggable" due to their flat surfaces and disordered domains. Recently, the identifica...
Rational Design of Antimony-Based Zintl Clusters: Unveiling Unconventional Bonding and Architectures [0.03%]
基于抗伯努利锌晶体的合理设计：揭示非常规键合和结构
Yi Lai,Wei-Xing Chen,Wen-Juan Tian et al.
Yi Lai et al.
ConspectusThe past decade has witnessed rapid growth in the synthesis of main-group element clusters, driven by advances in the design of Zintl phase precursors and their integration with organometallic reagents. These strategies have unloc...
Peptide/Protein Functionalization and Macrocyclization via Alkyne Umpolung with Hypervalent Iodine Reagents [0.03%]
含hyper-valent碘试剂的端炔 umpolung反应在多肽/蛋白质多功能化及大环化合物合成中的应用
Xing-Yu Liu,Jerome Waser
Xing-Yu Liu
ConspectusAlkynes are one of the most fundamental functional groups in organic synthesis due to the versatile chemistry of the triple bond, their unique rigid structure, and their use in bioconjugation. The introduction of alkynes onto orga...