Astroglia disturbances during development of the central nervous system in fetuses with Down's syndrome [0.03%]
唐氏综合征胎儿中枢神经系统发育过程中的星形胶质细胞异常
Grzegorz Zdaniuk,Teresa Wierzba-Bobrowicz,Grażyna M Szpak et al.
Grzegorz Zdaniuk et al.
Down's syndrome (DS), caused by aneuploidy of chromosome 21, is the most common chromosomal disorder. The most significant symptom of this disorder is mental retardation. Neuropathological changes found in the DS central nervous system (CNS...
Radiation-induced lowered neurogenesis associated with shortened latency of inhibitory avoidance memory response [0.03%]
辐射诱导的神经发生降低与抑制性回避记忆反应潜伏期缩短有关
Mehrdad Jahanshahi,Alireza Khoshbin Khoshnazar,Nasrin-Sadat Azami et al.
Mehrdad Jahanshahi et al.
The neural system is less sensitive to radiation than other late-responding organs and tissues such as the kidney and lung. The generation of new neurons in the adult mammalian brain has been documented in several works. Many studies show t...
Analysis of the prognostic significance of selected morphological and immunohistochemical markers in ependymomas, with literature review [0.03%]
星形细胞瘤的预后标志物分析及文献回顾
Antoni Zawrocki,Ewa Iżycka-Świeszewska,Wielisław Papierz et al.
Antoni Zawrocki et al.
Aim: Ependymal tumours are relatively uncommon primary neoplasms of the central nervous system. Histological criteria distinguishing ependymoma and anaplastic ependymoma are not clear-cut and other parameters are required...
Review
Folia neuropathologica. 2011;49(2):94-102. DOI: 2011
Expression of mutated isocitrate dehydrogenase-1 in gliomas is associated with p53 and EGFR expression [0.03%]
异柠檬酸脱氢酶-1突变在胶质瘤中的表达与p53和EGFR的表达相关性研究
Peter Birner,Kalina Toumangelova-Uzeir,Sevdalin Natchev et al.
Peter Birner et al.
Gliomas are the most common primary brain tumours. Several independent studies have shown that isocitrate dehydrogenase 1 (IDH1) mutation in diffuse gliomas is associated with a more favourable patient outcome. The aim of this study was to ...
Mechanisms related to neuron injury and death in cerebral hypoxic ischaemia [0.03%]
脑缺血缺氧性神经元损伤和死亡的机制研究
Min-Fang Guo,Jie-Zhong Yu,Cun-Gen Ma
Min-Fang Guo
Cerebral hypoxic-ischaemic injury is involved in many central nervous system diseases. The mechanisms of neuron injury and death in cerebral hypoxic ischaemia remain unclear. There have been many theories on pathogenesis of neuron injury an...
Review
Folia neuropathologica. 2011;49(2):78-87. DOI: 2011
Clinical and neuropathological picture of ethylmalonic aciduria - diagnostic dilemma [0.03%]
乙基马来酸尿症的临床和神经病理特征及其诊断困境
Ewa Jamroz,Justyna Paprocka,Dariusz Adamek et al.
Ewa Jamroz et al.
Increased ethylmalonic acid (EMA) in urine is a non-specific finding, and is observed in a number of inborn errors of metabolism, as well as in individuals who carry one of two common polymorphisms identified in the SCAD coding region. The ...
Case Reports
Folia neuropathologica. 2011;49(1):71-7. DOI: 2011
Anna Fidziańska,Ewa Walczak,Paweł Bekta et al.
Anna Fidziańska et al.
We performed ultrastructural testing of a cardiac biopsy taken from a heart with amyloidosis in which transthyretin mutation and light chain A amyloidosis were excluded. Cardiomyocytes of the affected heart showed accumulation of endosomal-...
Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria) [0.03%]
MEGDEL综合症(莱格病,耳聋,3-甲基谷光酸尿)患者成纤维细胞中活性氧(ROS)生成增多及过氧化氢酶水平降低
Agnieszka Karkucinska-Wieckowska,Magdalena Lebiedzinska,Elżbieta Jurkiewicz et al.
Agnieszka Karkucinska-Wieckowska et al.
Association of 3-methylglutaconic aciduria (3-MGCA) with sensorineural deafness and Leigh-like encephalopathy (MEGDEL) was described as a very rare mitochondrial disorder without a known molecular background. We present clinical and biochem...
Case Reports
Folia neuropathologica. 2011;49(1):56-63. DOI: 2011
Differential expression of calbindin D28k, calretinin and parvalbumin in the cerebellum of pups of ethanol-treated female rats [0.03%]
酒精处理雌性大鼠后代小脑钙结合蛋白D28k、钙调蛋白和 parvalbumin的差异表达
Teresa Wierzba-Bobrowicz,Eliza Lewandowska,Tomasz Stępień et al.
Teresa Wierzba-Bobrowicz et al.
Three calcium-binding proteins (CaBPs), calbindin D28k, calretinin and parvalbumin, were immunohistochemically examined in the cerebellum of ten-day-old rat pups of ethanol-treated dams. Dams were treated with ethanol during pregnancy and/o...
Subependymal giant cell astrocytomas with atypical histological features mimicking malignant gliomas [0.03%]
具有非典型组织学特征的室管膜下巨细胞星形细胞瘤模仿恶性胶质瘤
Wiesława Grajkowska,Katarzyna Kotulska,Elżbieta Jurkiewicz et al.
Wiesława Grajkowska et al.
Subependymal giant cell astrocytoma (SEGA) is a rare, benign brain tumour developing in patients with tuberous sclerosis complex (TSC). Typical histopathological findings of this neoplasm are solid sheets and perivascular pseudorosettes of ...
Case Reports
Folia neuropathologica. 2011;49(1):39-46. DOI: 2011