Some markers of neuronal damage in cerebrospinal fluid of multiple sclerosis patients in relapse [0.03%]
复发性多发性硬化患者脑脊液中部分神经元损伤标志物的改变
Krystyna Mitosek-Szewczyk,Wanda Gordon-Krajcer,Dorota Flis et al.
Krystyna Mitosek-Szewczyk et al.
In this paper the performance of cerebrospinal fluid (CSF) protein biomarkers important for monitoring damage of brain astrocytes and neurons for MS is reviewed. We estimated neurofilament, tau and phospho-tau proteins, β-APP, Aβ, S-100B ...
Ewa Matyja,Wiesława Grajkowska,Paweł Nauman et al.
Ewa Matyja et al.
Papillary tumour of the pineal region (PTPR) is a rare neoplasm that has been formally included in the 2007 WHO classification of central nervous system tumours. The critical diagnosis of this neoplasm is often difficult because of its simi...
Case Reports
Folia neuropathologica. 2011;49(3):181-90. DOI: 2011
Ultrastructure of granular osmiophilic material deposits (GOM) in arterioles of CADASIL patients [0.03%]
CADASIL患者动脉中层颗粒类脂质沉积物(GOM)的超微结构
Eliza Lewandowska,Dorota Dziewulska,Magdalena Parys et al.
Eliza Lewandowska et al.
Granular osmiophilic material (GOM) is a pathognomonic feature of CADASIL that may be a consequence of pathological processes triggered by Notch3 mutations. Since knowledge of the effects of CADASIL-associated GOM deposits is important to u...
Ultrastructural pathology of cortical capillary pericytes in human traumatic brain oedema [0.03%]
人类创伤性脑水肿皮质毛细血管周细胞的超微病理学变化
Orlando J Castejón
Orlando J Castejón
In human traumatic brain oedema pericytes exhibit remarkable oedematous changes, increased vacuolar and vesicular transport, transient transpericytal channels, and tubular structures demonstrating pericyte brain barrier dysfunction. They sh...
Review
Folia neuropathologica. 2011;49(3):162-73. DOI: 2011
Spatial patterns of β-amyloid (Aβ) deposits in familial and sporadic Alzheimer's disease [0.03%]
早老性和散发性阿尔茨海默病中β淀粉样蛋白(Aβ)沉积的分布模式
Richard A Armstrong
Richard A Armstrong
The spatial patterns of the diffuse, primitive, and classic β -amyloid (Aβ) deposits were compared in cortical regions in early-onset familial Alzheimer's disease (EO-FAD) linked to mutations of the amyloid precursor protein APP) or prese...
Rosiglitazone protects the dorsal root ganglion cells and sciatic nerve after crush in rat [0.03%]
罗格列酮对挤压伤后坐骨神经和 dorsal root ganglion 细胞的保护作用
Ali Noorafshan,Khatoon Shariat,Saied Karbalay-Doust et al.
Ali Noorafshan et al.
The aim of this study was to investigate the histological changes in the dorsal root ganglion (DRG) and the sciatic nerve in rats after sciatic nerve crush (SNC) and treatment with rosiglitazone. The rats were divided into four groups, each...
Interleukin 17 receptor in multiple sclerosis patients treated with interferon β-1a [0.03%]
干扰素β-1a治疗的多发性硬化症患者中的白细胞介素17受体研究
Grażyna Michałowska-Wender,Justyna Biernacka-Łukanty,Zofia Lasik et al.
Grażyna Michałowska-Wender et al.
Interleukin 17 (IL-17) and its receptor IL-17R1 produced by T-helper cells named Th17 are involved in the pathology of autoimmune diseases. In contrast to the at least partially explained role of IL-17 in pathology of multiple sclerosis, th...
Presence of L-kynurenine aminotransferase III in retinal ganglion cells and corpora amylacea in the human retina and optic nerve [0.03%]
人视网膜和视神经中视网膜节细胞和角质小体中L-犬尿氨酸胺转移酶III的存在
Robert Rejdak,Carmen Rummelt,Eberhart Zrenner et al.
Robert Rejdak et al.
Background: Corpora amylacea (CAm) are a hallmark of aging and neurodegeneration. The presence of kynurenine aminotransferases I and II (KAT I and II) in CAm in the human retina and optic nerve has been already shown. The...
Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-αlpha proteins in peripheral lymphocytes of patients with Alzheimer's disease [0.03%]
阿尔茨海默病患者外周淋巴细胞8-羟基鸟嘌呤DNA糖苷酶1(OGG1)的表达及p53、TNF-α蛋白水平
Mateusz Dezor,Jolanta Dorszewska,Jolanta Florczak et al.
Mateusz Dezor et al.
The aim of the study was to determine the extent of oxidative DNA damage (levels of 8-oxo2dG) and expression of OGG1 and p53 and TNF-α proteins in lymphocytes of Alzheimer's disease (AD) patients and a control group. The studies were condu...
Research on alteration of neurons in vagal nuclei in medulla oblongata in newborns with respiratory distress [0.03%]
新生儿呼吸窘迫伴脑干迷走神经核团神经元改变的实验研究
Hilmi Islami,Ragip Shabani,Driton Shabani et al.
Hilmi Islami et al.
Neuronal and axonal degenerative changes in motor vagal neurons (DMNV) and sensory vagal neurons (nTS) in the medulla oblongata in newborns were studied. Material was taken from the autopsies of newborns, live and dead newborns, in differen...