ZDHHC16 promoted neurocyte ferroptosis by suppression of CREB in a cerebral apoplexy model [0.03%]
ZDHHC16通过抑制CREB促进脑中风模型中铁死亡
Dongmei Xu,Hua Liu,Xiaoyu Deng et al.
Dongmei Xu et al.
Introduction: The present study explored the effects and possible mechanisms of ZDHHC16 in a model of cerebral apoplexy (CA). Material and methods: ...
The crosstalk effect of cancer stem cells in the progression of pediatric medulloblastoma through signaling expression of CD133, CD44, and OCT4 with and without Wnt-b-catenin activation [0.03%]
癌症干细胞在儿童髓母细胞瘤进展中的交互作用通过CD133，CD44和OCT4信号表达以及Wnt-b-连环蛋白激活的存在与否
Maher Kurdi,Alaa Alkhotani,Motaz Fadul et al.
Maher Kurdi et al.
Introduction: Cancer stem cells (CSCs) are principal drivers in medulloblastoma (MB) initiation, growth, and progression. Our study aimed to explore the expression of CD133, CD44, and OCT4 signaling markers and their effe...
Classification of gliomas based on genome-wide DNA methylation profiles and immunohistochemical analysis: a short study [0.03%]
基于全基因组DNA甲基化谱和免疫组织化学分析的胶质瘤分类：一项简短的研究
Olga Taryma-Leśniak,Kamil Buczkowski,Tomasz Klepinowski et al.
Olga Taryma-Leśniak et al.
Methylation profiling is one of the diagnostic methods included in the 2021 World Health Organization Classification of Central Nervous System Tumors (WHO CNS5). In the present short study, we performed methylation analysis of 16 archival d...
S1P receptor modulators affect the toxicity of amyloid β oligomers in microglial and neuronal cells [0.03%]
S1P受体调节剂影响Aβ寡聚物对小胶质细胞和神经元的毒性作用
Iga Wieczorek,Robert P Strosznajder
Iga Wieczorek
A large body of evidence has shown that the amyloid b peptide oligomers (Abo) are predominantly responsible for the neurodegeneration/cognitive impairments in Alzheimer's disease (AD). Abo cause mitochondrial dysfunctions leading to an imba...
A meta-analysis and systematic review of the association between cortisol and the beginning of depression symptoms in adolescents and young adults [0.03%]
皮质醇与青少年和年轻成人抑郁症症状开始之间的关联的荟萃分析和系统评价
Wenling Li,Zheng Huang,Ruqi Zhang et al.
Wenling Li et al.
Introduction: The incidence of major depressive disorder (MDD) in adults has been associated with dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to elevated secretion of cortisol. However, limited...
The potential contributions of matrix metalloproteinase 8,9 and 13 (MMP-8,9,13) to cerebral vasospasm and the role of doxycycline inhibitors on gene expression after experimental subarachnoid haemorrhage [0.03%]
基质金属蛋白酶8、9和13（MMP-8，9，13）在脑血管痉挛中的潜在作用及实验性蛛网膜下腔出血后多西环素抑制剂对基因表达的影响
Yasin Göktürk,Sule Gokturk,Suat E Çelik
Yasin Göktürk
Introduction: Vasospasm has been reported as the most important cause of mortality and morbidity in patients with subarachnoid haemorrhage (SAH) who can reach the hospital. Matrix metalloproteinases (MMPs) are a gene fami...
Glial fibrillary acidic protein and S100b protein immunoreactivity in the hippocampus of weaning rats from dams treated with acrylamide during pregnancy [0.03%]
妊娠期母鼠摄入丙烯酰胺对新生断奶大鼠海马区胶质纤维酸性蛋白和S-100β蛋白的影响
Karol Rycerz,Aleksandra E Krawczyk,Jadwiga Jaworska-Adamu et al.
Karol Rycerz et al.
Acrylamide is formed at high temperature during preparation of food rich in carbohydrates. It can be found in animal feed based on potatoes and granulated wheat subjected to thermal treatment. It was demonstrated that acrylamide has a neuro...
Minimizing hemorrhagic and perioperative complications in deep brain stimulation surgery in a series of 191 patients operated on over 4 years [0.03%]
立体脑深部电刺激手术中减少出血及术源性并发症(四年来191例总结)
Michał Sobstyl,Angelika Stapińska-Syniec,Wiktor Paskal
Michał Sobstyl
Introduction: Intracranial hemorrhage (ICH) in functional neurosurgery is a relatively rare but serious complication. One of the possible risk factors related to ICH is the number of trajectories made for microelectrode r...
Alterations in mRNA level of proteins related to redox state and mitochondria in an Alzheimer's disease animal model: Promising targets in neuroprotection [0.03%]
阿尔茨海默病动物模型中与氧化还原状态和线粒体相关的蛋白质的mRNA水平变化：神经保护作用的潜在靶点
Sylwia Żulińska,Przemysław L Wencel,Kinga Czubowicz et al.
Sylwia Żulińska et al.
Oxidative stress and disturbances of mitochondrial function in the brain play a crucial role in Alzheimer's disease (AD). However, little is known about the dynamics of these changes in different parts of the brain at the early stage of AD....
Exposure of cerebellar granule cells to nanosilver: Oxidative stress parameters and the protective effect of exogenous glutathione [0.03%]
纳米银对小脑颗粒细胞的作用：氧化应激参数及外源性谷胱甘肽的保护作用
Lidia Struzynska,Beata Toczylowska,Beata Dabrowska-Bouta et al.
Lidia Struzynska et al.
In recent decades, the production of silver nanoparticles (AgNPs) has shown exponential growth. They are widely used as high-potency antimicrobial agents in a range of medical and consumer products and increasingly in the agricultural secto...