Batatasin-III protects cerebral vascular endothelium by regulating mitochondrial function and production of nitric oxide [0.03%]
巴塔西宁通过调节线粒体功能及一氧化氮的产生保护脑血管内皮细胞
Zhuyan Huang,Ling Li,Shanshan Huang et al.
Zhuyan Huang et al.
This study assessed the effect of batatasin-III on cerebral microvascular endothelial cell (EC) injury. Endothelial cell injury was induced in isolated cells by oxygenglucose deprivation/reperfusion (OGD/R) conditions. During 4 h of OGD ins...
LINC00900 as a poor prognostic factor in gliomas regulates tumor progression via negatively modulating miR-186-5p [0.03%]
长链非编码RNA LINC00900通过负向调节miR-186-5p在胶质瘤不良预后及肿瘤进展中的作用研究
Peikai Zhang,Qi Mao,Youpei Wang et al.
Peikai Zhang et al.
Introduction: Glioma is the most prevalent primary brain tumor, causing significant mortality and morbidity. lncRNAs have great potential in tumor-targeted therapy, including for glioma via sponging microRNAs. Previous st...
Jacek Gulczyński,Rosa H Gouveia,David Sunnucks et al.
Jacek Gulczyński et al.
Anatomical studies of the brain and successive analyses of this organ were performed in ancient times. Indeed, notes found in the Edwin Smith Papyrus mention that the Egyptians identified the meninges and gyri millennia ago. Their successor...
Clinicopathological and neuroradiological presentation in an immuno-deficiency patient with central nervous system recurrence of Burkitt lymphoma: an extremely rare case with complete remission achieved twice after GMALL-B-ALL/NHL2002 and R-MIV protocols [0.03%]
免疫功能不全患者中枢神经系统伯基特淋巴瘤复发的临床病理及神经影像特征:一例两次获得完全缓解的罕见病例(GMALL-B-ALL/NHL2002和R-MIV方案)
Piotr Glinka,Michał Sobstyl,Grzegorz Rymkiewicz et al.
Piotr Glinka et al.
Burkitt lymphoma (BL) is a specific, rare (1-2% of all cases of lymphoma) and aggressive type of B-cell non-Hodgkin lymphoma. If BL recurs during treatment, it usually becomes drug-resistant to subsequent treatment regimens and the prognosi...
Case Reports
Folia neuropathologica. 2025;63(2):198-208. DOI:10.5114/fn.2025.152574 2025
Efficacy of Buyang Huanwu Decoction in treating acute ischemic stroke based on the neurovascular unit [0.03%]
基于神经血管单元理论补阳还五汤治疗急性缺血性卒中有效性的机制研究
Qingyang Dong
Qingyang Dong
Introduction: The aim of the study was to investigate the clinical efficacy of Buyang Huanwu Decoction (BHD) in the treatment of patients who had an acute ischemic stroke (AIS). ...
Randomized Controlled Trial
Folia neuropathologica. 2025;63(2):157-165. DOI:10.5114/fn.2025.151207 2025
Neuregulin 2 reversed astrocytosis in the spinal cord in a mouse model of Alzheimer's disease [0.03%]
神经调节蛋白2逆转阿尔茨海默病小鼠模型脊髓星形胶质增生现象
Chong Liu,Qing Xie,Jun-Ping Xu et al.
Chong Liu et al.
Introduction: Alzheimer's disease (AD) is classified as a neurodegenerative disorder without efficacious therapeutic interventions. Accumulating evidence has demonstrated the deposition of b-amyloid peptide (Ab) in the sp...
Effect of the TGF-b signaling pathway on spinal cord ependymoma: A study based on bioinformatics analysis and clinical trials [0.03%]
转化生长因子-β信号通路对脊髓室管膜瘤的影响:基于生物信息学分析和临床试验的研究
Yan-Dong Fan,Man-Li Zhu,Mamutijiang Muertizha et al.
Yan-Dong Fan et al.
This study aimed to identify potential therapeutic targets for spinal cord ependymoma (SCE) and key signaling pathways associated with the transforming growth factor b (TGF-b) signaling pathway through bioinformatics analysis, molecular bio...
Alzheimer's disease-related a-synuclein gene expression in CA3 subfield of hippocampus in post-ischemic brain during 2-year survival [0.03%]
脑缺血后海马CA3亚区与阿尔茨海默病相关的α-突触核蛋白基因表达两年生存期内变化规律的研究
Ryszard Pluta,Anna Bogucka-Kocka,Jacek Bogucki et al.
Ryszard Pluta et al.
In this study, we investigated whether changes in the expression of the a-synuclein gene occur and participate in post-ischemic brain neurodegeneration of Alzheimer's disease phenotype. The current study assessed the expression of the a-syn...
Nab-paclitaxel: A revolution in the nano-therapeutic approach to IDH-wildtype glioblastoma [0.03%]
纳米 nab-紫杉醇:IDH 野生型胶质母细胞瘤治疗的革命性疗法
Maria Fareed Siddiqui,Amber Hassan,Muzna Tahir et al.
Maria Fareed Siddiqui et al.
Paclitaxel (PTX) is a potent chemotherapy drug commonly used to treat various solid tumours, including breast and ovarian cancers. However, its effectiveness in treating IDH-wildtype glioblastoma has been limited due to challenges crossing ...
STAT3 induces amygdala apoptosis by regulating the expression of stathmin in the rat model of posttraumatic stress disorder [0.03%]
STAT3通过调控星状螺胞蛋白表达诱导 PTSD大鼠模型杏仁核凋亡
Wenqiang Liu,Anqi Liu,Shengxue Yu et al.
Wenqiang Liu et al.
Introduction: Stathmin, recognised as the protein associated with the disassembly of microtubules, plays a vital role in the modulation of human fear as well as anxiety responses. However, it is unclear whether stathmin r...