Targeting brain injury in sepsis: How remimazolam modulates the TLR4/NF-κB pathway in rats [0.03%]
针对脓毒症脑损伤的机制研究及右美托咪定干预的效果评价：TLR4/NF-κB信号通路的作用及其机制研究
Quan-Hui Dong,Xiao-Shi Liu,Shu-Ting Liu et al.
Quan-Hui Dong et al.
Sepsis-associated brain injury can lead to severe neurobehavioral and cognitive impairments due to inflammation, oxidative stress, and blood-brain barrier (BBB) dysfunction. Remimazolam (RM), a novel benzodiazepine, may have therapeutic pot...
Comprehensive analysis of ferroptosis and its correlation with peripheral immune infiltration in epileptic patients [0.03%]
癫痫患者的铁死亡综合分析及其与外周免疫浸润的相关性研究
Dongjuan Yuan,Zhenzhen Qu,Zhuofeng Mao et al.
Dongjuan Yuan et al.
Introduction: Aim of the study was to explore the association between ferroptosis genes in peripheral blood and immune infiltration in epileptic patients. ...
NAD+ attenuates central nervous system demyelination in experimental autoimmune encephalomyelitis mice [0.03%]
烟酰胺腺嘌呤二核苷酸减轻实验性自身免疫性脑脊髓炎小鼠中枢神经系统脱髓鞘症状
Bin Zheng,Jianhua Ma,Xiao Deng et al.
Bin Zheng et al.
Nicotinamide adenine dinucleotide (NAD + ) supplementation attenuates demyelination in the experimental autoimmune encephalomyelitis (EAE) model. The aim of the study was to confirm the therapeutic effect of NAD + on the EAE model and inves...
Xin Hu,Hong Xu,Yang Han et al.
Xin Hu et al.
Vitamin B 12 deficiency can cause subacute combined degeneration of the spinal cord and cerebellar lesions. The patient, a 78-year-old woman, presented with an unstable gait, speech impairment and memory decline for one month. The neurologi...
Case Reports
Folia neuropathologica. 2025;63(3):320-326. DOI:10.5114/fn.2025.152518 2025
Displacement of the deep brain stimulation electrodes implanted in the anterior nucleus of the thalamus due to chronic subdural hematoma [0.03%]
前核慢性硬膜下血肿致脑深部刺激电极移位
Michał Sobstyl,Karol S Karamon,Ewa Nagańska et al.
Michał Sobstyl et al.
Anterior nucleus of the thalamus deep brain stimulation (ANT DBS) offers a treatment option for patients with drug-resistant epilepsy (DRE). This treatment modality is particularly useful in cases of multifocal DRE originating from the fron...
Case Reports
Folia neuropathologica. 2025;63(3):313-319. DOI:10.5114/fn.2025.154802 2025
Thoracic spinal cord compression due to excessive scarring around surgical paddle epidural electrodes. Report of two cases with literature review [0.03%]
术前硬模外电极植入导致胸段脊髓压迫的两例报告及文献复习
Michał Sobstyl,Karol S Karamon,Kasper Sipowicz et al.
Michał Sobstyl et al.
Introduction: Spinal cord stimulation (SCS) is considered an efficient and safe method of treating intractable chronic pain from various origins such as persistent spinal pain syndrome (PSPS) or complex regional pain synd...
Application of a convolutional neural network model to construct an automatic, AI-based identification system for rat kidney tissue microscopic images [0.03%]
基于卷积神经网络的小鼠肾脏组织病理图像智能识别系统研究
Chen Yun,Ai-Yun Zha,Xiaofan He et al.
Chen Yun et al.
The aim was to develop an artificial intelligence (AI)-based identification system using a deep learning method based on convolutional neural networks to analyze pathological kidney images. We constructed a rat chronic kidney disease (CKD) ...
Retrospective analysis of intervertebral disc degeneration with neovascularization and histopathological findings in surgically treated patients [0.03%]
回顾性分析接受手术治疗的患者椎间盘退变与新生血管和组织病理学特征之间的关系
Yasin Göktürk,Şule Göktürk,Arzu E Taşdemir et al.
Yasin Göktürk et al.
Introduction: Intervertebral discs are generally known as the body's largest avascular structures. In the human body, there is not yet a collective resource characterizing intervertebral vascularization. When an intervert...
MiR-182 ameliorates neuropathic pain by enhancing the transition from M1 to M2 phenotype polarization via PI3K/AKT signaling [0.03%]
miR-182通过PI3K/AKT信号促进M1型小胶质细胞向M2表型极化转换从而缓解神经痛
Fang Cheng,Aixing Yang,Fengfeng Yan et al.
Fang Cheng et al.
Neuropathic pain (NP), a severe nervous system ailment, is affected by microRNA's role in microglial polarization. MiR-182 helps ease this pain, particularly from spared nerve injury, but its regulatory mechanism remains poorly understood. ...
LncRNA RMST contributes to neuroinflammation after traumatic brain injury by targeting miR-139-5p [0.03%]
长链非编码RNA RMST通过靶向miR-139-5p参与创伤性脑损伤后的神经炎症反应
Yangwei Zhang,Yinhua Chen,Yanli Zhang et al.
Yangwei Zhang et al.
Introduction: Neuroinflammation plays a significant role in the pathological progression of traumatic brain injury (TBI) and represents a promising therapeutic target. The present study focused on exploring the mechanism ...