Antinociceptive effects of the essential oil of Dracocephalum kotschyi in the mouse writhing test [0.03%]
Dracocephalum kotschyi 驱痛精油的抗驱痛作用在小鼠扭体试验中的作用
Samira Golshani,Fariba Karamkhani,Hamid Reza Monsef-Esfehani et al.
Samira Golshani et al.
Purpose: Dracocephalum kotschyi is a wild-growing flowering plant belonging to the family Labiatae and found abundantly in Iran. This plant has been used in Iran folk medicine as analgesic. ...
Studies on anti-diarrhoeal activity of Calotropis gigantea R.Br. in experimental animals [0.03%]
粗茎野生草寄生抗腹泻作用的研究
Havagiray R Chitme,Mehrdad Chandra,Sadhna Kaushik
Havagiray R Chitme
Purpose: Calotropis gigantea R. Br. (Asclepiadaceae) a wildly growing plant has been reported to possess number of medicinal properties and other purposes. The purpose of the present study was to evaluate scientifically t...
Antinociceptive effects of Peganum harmala L. alkaloid extract on mouse formalin test [0.03%]
植物peganum harmala l. 碱提取物的抗痛风效果研究
Hamid Reza Monsef,Ali Ghobadi,Mehrdad Iranshahi et al.
Hamid Reza Monsef et al.
Purpose: To evaluate the effect of Peganum harmala (Syrian rue) a wild-growing flowering plant belonging to the family Zygophylaceae and found abundantly in Iran on formalin-induced pain response in mice. ...
Assessment of enzymatic cleaning agents and disinfectants against bacterial biofilms [0.03%]
酶清洗剂和消毒剂对细菌生物被膜的评估
Mona Augustin,Terhi Ali-Vehmas,Faik Atroshi
Mona Augustin
Purpose: Microbial biofilm has become difficult to control by antibiotic and biocide regimes that are effective against suspended bacteria. Their colonization of surfaces can be a problem and is generally controlled throu...
Reza Mehvar,Anjaneya P Chimalakonda
Reza Mehvar
Purpose: To develop an isolated perfused rat liver model to study the hepatic disposition of cyclosporine A (CyA) in both sexes. Methods: ...
In vitro cytotoxicity studies of hydrogel pullulan nanoparticles prepared by AOT/N-hexane micellar system [0.03%]
AOT/正己烷胶束体系制备的葡聚糖纳米粒的体外细胞毒性研究
Mona Gupta,Ajay Kumar Gupta
Mona Gupta
Purpose: The purpose of this study was to prepare crosslinked pullulan nanoparticles encapsulating bioactive molecules inside the aqueous core of Aerosol-OT/n-hexane reverse micellar droplets with narrow size distribution...
Systemic bone formation with weekly PTH administration in ovariectomized rats [0.03%]
卵巢切除大鼠间歇性甲状旁腺激素治疗的全身性骨形成效应
Sébastien A Gittens,Gregory R Wohl,Ronald F Zernicke et al.
Sébastien A Gittens et al.
Purpose: Weekly subcutaneous administration of 0 (vehicle), 10 and 80 microg/kg doses of human parathyroid hormone (1-34) [PTH (1-34)] were compared based on their capacity to induce systemic formation of bone in 9 month-...
Definition of a novel atomic index for QSAR: the refractotopological state [0.03%]
新型原子指数用于QSAR的定义：折射立体学状态
Ramon Carrasco-Velar,J A Padrón,J Gálvez
Ramon Carrasco-Velar
Purpose: In this work, a novel descriptor of atoms in molecules is introduced. The Refractotopological State Index for atoms (R-state,R), rectifies the atomic refractivity values reported by Crippen et al with the atomic ...
Tatsuya Itoh,Isao Takemoto,Shirou Itagaki et al.
Tatsuya Itoh et al.
Purpose: The aim of this study was to investigate the excretion of irinotecan hydrochloride (CPT-11) and its metabolites into the gastrointestinal lumen via the biliary route after intravenous administration of lactone an...
Effect of a lipoidic excipient on the absorption profile of compound UK 81252 in dogs after oral administration [0.03%]
一种助脂剂对UK 81252口服给药后在狗体内吸收过程的影响研究
Rong-Kun Chang,Amir H Shojaei
Rong-Kun Chang
Purpose: Effect of caprylocaproyl macrogolglycerides (Labrasol), as a lipoidic excipient/vehicle in an oral capsule formulation, on pharmacokinetic disposition of a BCS Class 3 compound, UK-81252, was investigated in vivo...