Adapting artificial intelligence into the evolution of pharmaceutical sciences and publishing: Technological darwinism [0.03%]
人工智能在药学科学和出版业发展中的应用：技术达尔文主义
Neal M Davies
Neal M Davies
Grading pharmacists' risk of complaints to a regulator: A retrospective cohort study [0.03%]
药剂师向监管机构投诉风险的分级：一项回顾性队列研究
Katherine Morris,Matthew J Spittal
Katherine Morris
Background: Tools to grade risk of complaint to a regulatory board have been developed for physicians but not for other health practitioner groups, including pharmacists. We aimed to develop a score that classified pharmacists into low, med...
Shared decision-making practices and patient values in pharmacist outpatient care for rheumatic disease: A multiple correspondence analysis [0.03%]
风湿病药学门诊的共同决策实践与患者价值观：多重对应分析法研究
Ikkou Hirata,Shunsuke Hanaoka,Ryo Rokutanda et al.
Ikkou Hirata et al.
Purpose: To investigate the value-to-value relationships, relationship between values and patient background, continuation rate of treatment after shared decision-making (SDM), and disease status in order to clarify the values involved in d...
The role of CYP2C9*2, CYP2C9*3 and VKORC1- 1639 variants on the susceptibility of upper gastrointestinal bleeding: A full case-control study [0.03%]
CYP2C9*2、CYP2C9*3和VKORC1-1639基因多态性与消化性出血的相关性研究：全病例对照研究
Marcela Forgerini,Gustavo Urbano,Tales Rubens De Nadai et al.
Marcela Forgerini et al.
Purpose: To investigate whether interindividual variability in the CYP2C9 (*2 and *3 alleles) and VKORC1 (rs9923231) genes is associated with increased risk of upper gastrointestinal bleeding (UGIB) in users of non-steroidal anti-inflammato...
Effects of dual therapy with betamethasone and tetracycline in a NC/Nga mouse model of atopic dermatitis [0.03%]
倍他米松联合四环素治疗NC/Nga小鼠过敏性皮炎的疗效观察
Katsuhiko Matsui,Mahoka Kobayashi,Mari Nagano et al.
Katsuhiko Matsui et al.
Purpose: Our previous study has demonstrated that tetracycline exerts excellent bactericidal activity against Staphylococcus aureus strains isolated from patients with atopic dermatitis (AD) while simultaneously inhibiting the development o...
Gastrointestinal perforation associated with novel antineoplastic agents: A real-world study based on the FDA Adverse Event Reporting System [0.03%]
基于FDA不良事件报告系统的新型抗肿瘤药物相关胃肠穿孔的真實世界研究
Zicheng Yu,Haibin Zhu,Hongjun Chen et al.
Zicheng Yu et al.
Purpose: Gastrointestinal perforation (GIP) is a fatal adverse event (AE). The AE of GIP induced by novel antineoplastic agents has attracted attention recently. We aimed to explore the AE signals of GIP related to novel antineoplastic agen...
The mechanism of Leonuri Herba in improving polycystic ovary syndrome was analyzed based on network pharmacology and molecular docking [0.03%]
基于网络药理学和分子对接技术分析Leonurus japonicus Houtt改善多囊卵巢综合征的机制
Mali Wu,Hua Liu,Jie Zhang et al.
Mali Wu et al.
Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder affecting women. Chinese herbs have been considered as an alternative treatment for PCOS, and Yi-mu-cao (Leonuri Herba) is one of the most commonly used he...
Remdesivir-induced conduction abnormalities: A molecular model-based explanation [0.03%]
瑞德西韦引起的心脏传导异常：基于分子模型的解释
Ryan Kingsley,Christopher Rohlman,Ashley Otto et al.
Ryan Kingsley et al.
Purpose: Remdesivir use in COVID-19 is associated with cardiac conduction abnormalities from unclear mechanisms. A proposed mechanism is the bioaccumulation of the intermediate metabolite GS-441524 resulting in exogenous activation of cardi...
Drug-disease interaction: Clinical consequences of inflammation on drugs action and disposition [0.03%]
药物-疾病相互作用：炎症对药效和代谢的影响
Yasmeen El Hajj Abdallah,Sukhman Chahal,Fakhreddin Jamali et al.
Yasmeen El Hajj Abdallah et al.
Inflammation is a culprit in many conditions affecting millions of people worldwide. A plethora of studies has revealed that inflammation and inflammatory mediators such as cytokines and chemokines are associated with altered expression and...
Persistence and switching patterns of migraine prophylactic medications in Canada: A retrospective claims analysis comparing adherence and evaluating the economic burden of illness [0.03%]
加拿大偏头痛预防药物的用药持续性和换药模式：一项回顾性保险索赔分析，比较依从性并评估疾病经济负担
Andrew Ojo,Steven Zhang,Nataly Bleibdrey et al.
Andrew Ojo et al.
Purpose: To describe patient characteristics, treatment patterns, and the burden of illness among adult migraine patients in Canada prescribed migraine prophylactics. Little is known about the relative persistence of trea...