Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome [0.03%]
网络药理学和分子对接揭示了大黄牡丹汤治疗溃疡性结肠炎和肠易激综合症的免疫调节机制
Leilei Zhai,Weiming Yang,Dianrong Li et al.
Leilei Zhai et al.
Background: Ulcerative colitis (UC) and irritable bowel syndrome (IBS) share various similarities in clinical symptoms, pathogenesis, and treatment. UC concurrent IBS tends toward more severe symptoms and worse prognosis, and promising feas...
A new method for investigating bioequivalence of inhaled formulations: A pilot study on salbutamol [0.03%]
一种新的吸入制剂生物等效性研究方法：一项关于沙丁胺醇的试点研究
Homa Rezaei,Maryam Khoubnasabjafari,Vahid Jouyban-Gharamaleki et al.
Homa Rezaei et al.
Purpose: An efficient, cost-effective and non-invasive test is required to overcome the challenges faced in the process of bioequivalence (BE) studies of various orally inhaled drug formulations. Two different types of pressurized meter dos...
Occurrence of intraocular hemorrhages under monotherapy or combination therapy of antiplatelets and anticoagulants using the Japanese Adverse Drug Event Report database [0.03%]
基于日本药品不良反应报告数据库的抗血小板药和抗凝药单独或联合治疗的眼内出血事件分析
Junko Tanaka,Takenao Koseki,Kohsuke Sekido et al.
Junko Tanaka et al.
Purpose: An intraocular hemorrhage is an adverse event that can lead to visual acuity impairment. Antithrombotic therapy with antiplatelet agents and anticoagulants may increase intraocular hemorrhage. However, since their frequency is low,...
Adapting artificial intelligence into the evolution of pharmaceutical sciences and publishing: Technological darwinism [0.03%]
人工智能在药学科学和出版业发展中的应用：技术达尔文主义
Neal M Davies
Neal M Davies
Grading pharmacists' risk of complaints to a regulator: A retrospective cohort study [0.03%]
药剂师向监管机构投诉风险的分级：一项回顾性队列研究
Katherine Morris,Matthew J Spittal
Katherine Morris
Background: Tools to grade risk of complaint to a regulatory board have been developed for physicians but not for other health practitioner groups, including pharmacists. We aimed to develop a score that classified pharmacists into low, med...
Shared decision-making practices and patient values in pharmacist outpatient care for rheumatic disease: A multiple correspondence analysis [0.03%]
风湿病药学门诊的共同决策实践与患者价值观：多重对应分析法研究
Ikkou Hirata,Shunsuke Hanaoka,Ryo Rokutanda et al.
Ikkou Hirata et al.
Purpose: To investigate the value-to-value relationships, relationship between values and patient background, continuation rate of treatment after shared decision-making (SDM), and disease status in order to clarify the values involved in d...
The role of CYP2C9*2, CYP2C9*3 and VKORC1- 1639 variants on the susceptibility of upper gastrointestinal bleeding: A full case-control study [0.03%]
CYP2C9*2、CYP2C9*3和VKORC1-1639基因多态性与消化性出血的相关性研究：全病例对照研究
Marcela Forgerini,Gustavo Urbano,Tales Rubens De Nadai et al.
Marcela Forgerini et al.
Purpose: To investigate whether interindividual variability in the CYP2C9 (*2 and *3 alleles) and VKORC1 (rs9923231) genes is associated with increased risk of upper gastrointestinal bleeding (UGIB) in users of non-steroidal anti-inflammato...
Effects of dual therapy with betamethasone and tetracycline in a NC/Nga mouse model of atopic dermatitis [0.03%]
倍他米松联合四环素治疗NC/Nga小鼠过敏性皮炎的疗效观察
Katsuhiko Matsui,Mahoka Kobayashi,Mari Nagano et al.
Katsuhiko Matsui et al.
Purpose: Our previous study has demonstrated that tetracycline exerts excellent bactericidal activity against Staphylococcus aureus strains isolated from patients with atopic dermatitis (AD) while simultaneously inhibiting the development o...
Gastrointestinal perforation associated with novel antineoplastic agents: A real-world study based on the FDA Adverse Event Reporting System [0.03%]
基于FDA不良事件报告系统的新型抗肿瘤药物相关胃肠穿孔的真實世界研究
Zicheng Yu,Haibin Zhu,Hongjun Chen et al.
Zicheng Yu et al.
Purpose: Gastrointestinal perforation (GIP) is a fatal adverse event (AE). The AE of GIP induced by novel antineoplastic agents has attracted attention recently. We aimed to explore the AE signals of GIP related to novel antineoplastic agen...
The mechanism of Leonuri Herba in improving polycystic ovary syndrome was analyzed based on network pharmacology and molecular docking [0.03%]
基于网络药理学和分子对接技术分析Leonurus japonicus Houtt改善多囊卵巢综合征的机制
Mali Wu,Hua Liu,Jie Zhang et al.
Mali Wu et al.
Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder affecting women. Chinese herbs have been considered as an alternative treatment for PCOS, and Yi-mu-cao (Leonuri Herba) is one of the most commonly used he...