Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery [0.03%]
近年来聚合物微针促进长效透皮给药的研究进展
Fanda Meng,Xinyu Qiao,Chenglong Xin et al.
Fanda Meng et al.
Microneedle (MN)-assisted drug delivery technology has gained increasing attention over the past two decades. Its advantages of self-management and being minimally invasive could allow this technology to be an alternative to hypodermic need...
Alistair K C Chan,Nehil Ranjitham Gopalakrishnan,Yannick Leandre Traore et al.
Alistair K C Chan et al.
Additive manufacturing, commonly referred to as three-dimensional (3D) printing, has the potential to initiate a paradigm shift in the field of medicine and drug delivery. Ever since the advent of the first-ever United States Food and Drug ...
Real-world data: a comprehensive literature review on the barriers, challenges, and opportunities associated with their inclusion in the health technology assessment process [0.03%]
真实世界数据：系统回顾在卫生技术评估过程中纳入所面临的障碍、挑战和机遇
Konstantinos Zisis,Elpida Pavi,Mary Geitona et al.
Konstantinos Zisis et al.
Objective: This review aimed to assess the current use and acceptance of real-world data (RWD) and real-world evidence (RWE) in health technology assessment (HTA) process. It additionally aimed to discern stakeholders' viewpoints concerning...
Ali Ghayoor,Hamed Gilzad Kohan
Ali Ghayoor
This editorial explores how artificial intelligence (AI) is revolutionizing the science of pharmacokinetics (PK). It discusses the challenges of conventional PK analysis and how AI has transformed this area. It highlights the promise of art...
What a pain in the … back: a review of current treatment options with a focus on naproxen sodium [0.03%]
什么痛苦在…背部：当前治疗选择综述并重点关注钠盐naproxen的治疗
Steven M Weisman,Giovanni Ciavarra,Grant Cooper
Steven M Weisman
Non-specific low back pain (LBP) represents a challenging and prevalent condition that is one of the most common symptoms leading to primary care physician visits. While established guidelines recommend prioritizing non-pharmacological appr...
Catherine Y Lau
Catherine Y Lau
Effect of Oregon grape root extracts on P-glycoprotein mediated transport in in vitro cell lines [0.03%]
小檗根提取物对体外细胞模型中P-糖蛋白介导的转运的影响
Ying Fan,Zhu Zhou,Lei Zhang
Ying Fan
Purpose: This study aims to investigate the potential of Oregon grape root extracts to modulate the activity of P-glycoprotein. Methods: We performed 3H-CsA or 3H-digoxin transport experiments in the absence or presence of two sources of Or...
Comparing broad and narrow phenotype algorithms: differences in performance characteristics and immortal time incurred [0.03%]
广义和狭义表型算法的比较：性能特征及永生时间差异
Joel N Swerdel,Mitchell M Conover
Joel N Swerdel
Introduction: When developing phenotype algorithms for observational research, there is usually a trade-off between definitions that are sensitive or specific. The objective of this study was to estimate the performance characteristics of p...
Therapeutic update on oral potassium exchange resin use in chronic kidney disease patients: a systematic review of randomized controlled clinical trials [0.03%]
慢性肾脏病患者使用口服钾交换树脂的治疗效果更新：一项随机对照临床试验的系统评价
Jaclyn Gruver,Akram Al-Makki,Brian Shepler
Jaclyn Gruver
Hyperkalemia is a common electrolyte disorder in patients with chronic kidney disease (CKD) that increases in prevalence with the decline of glomerular fltration rate (GFR). Another risk of hyperkalemia is the use of renin-angiotensin-aldos...
Corrigendum: Applications of exhaled breath condensate analysis for drug monitoring and bioequivalence study of inhaled drugs [0.03%]
勘误表：吸入药物药代动力学和生物等效性研究中呼出气冷凝液的应用
Nastaran Hashemzadeh,Elaheh Rahimpour,Abolghasem Jouyban
Nastaran Hashemzadeh
[This corrects the article DOI: 10.18433/jpps33121.]. Keywords: bioequivalence; exhaled breath condensate; i...