Compounding and stability studies of liquid oral formulations of beta-blockers (bisoprolol, betaxolol, and nadolol) for paediatric patients [0.03%]
β受体阻滞剂(比索洛尔、贝他洛尔和纳多洛尔)液体制剂的复方及稳定性研究(用于儿科患者)
Laura Dubois,Cyrielle Bouguergour,Romain Paoli-Lombardo et al.
Laura Dubois et al.
In paediatric wards, bisoprolol, betaxolol, or nadolol can be administered orally at non-licensed dosages. To provide paediatric patients with appropriate treatment, batches of beta-blocker oral suspensions must be compounded, which involve...
Reuse of unused medications: a cross-sectional study on public willingness and influencing factors [0.03%]
关于药物再利用的横断面研究:公众意愿及影响因素分析
Faten Alhomoud,Sakinah Alalwyat,Lama Alanzi et al.
Faten Alhomoud et al.
Medication waste is a significant global concern with environmental, economic, and healthcare implications. In Saudi Arabia, approximately 25.8% of dispensed medications are wasted, resulting in an annual cost of $150 million. Re-dispensing...
Hypoglycemia and associated cardiovascular diseases, morbidity and mortality in patients with type 2 diabetes mellitus in university teaching hospitals in Rwanda [0.03%]
Rwanda大学教学医院中2型糖尿病患者的低血糖及相关的发病率和死亡率心血管疾病
Jean Baptiste Nyandwi,Pierre Celestin Munezero,Charles Uwambajimana et al.
Jean Baptiste Nyandwi et al.
Background: Hypoglycemia is a common yet underrecognized complication in patients with type 2 diabetes mellitus (T2DM), often linked with increased cardiovascular (CV) morbidity and mortality. Despite its clinical importa...
Standard formulas and individualised parenteral nutrition preparations in very low birth weight infants [0.03%]
极低出生体重儿的标准配方和个体化肠外营养准备
Laurie Dez,Stéphane Haÿs,Gilles Leboucher et al.
Laurie Dez et al.
Background/objectives: Optimal nutrition in very low birth weight (VLBW) infants is associated with improved clinical outcomes. When parenteral nutrition (PN) with a marketing authorisation is not appropriate, hospital ph...
Development of a submicron emulsion-based delivery system to improve the anti-inflammatory activity of urolithin A [0.03%]
基于亚微米乳剂递送系统开发提高 ellithin A抗炎活性的方法
Elisabetta Esposito,Valentyn Dzyhovskyi,Federico Santamaria et al.
Elisabetta Esposito et al.
Objective: Despite the antioxidant, anti-inflammatory, and anti-cellular-aging activities of urolithin A (UroA), a naturally occurring postbiotic, its high lipophilicity hampers its pharmaceutical application. To overcome...
Zaleplon nanospanlastics loaded transdermal patches: formulation, optimization, ex-vivo permeation, and in-vivo studies [0.03%]
zaleplon纳米颗粒经皮吸收贴剂:处方,优化,体外透皮及体内研究
Ahmed A El-Shenawy,Reham A Abd Elkarim,Reda A Mahmoud et al.
Ahmed A El-Shenawy et al.
Zaleplon (ZLP) is a commonly used sedative-hypnotic drug that has low oral bioavailability because of its poor water solubility and extensive hepatic metabolism. This study aimed to encapsulate ZLP into spanlastic nanovesicles to enhance it...
A survey of regulatory recommendations for waivers of in vivo bioequivalence studies of generic products for certain dosage forms by participating regulators and organisations of the International Pharmaceutical Regulators Programme. Part 2 [0.03%]
国际药品监管机构计划参与监管机构和组织对某些给药形式仿制药体内生物等效性研究豁免的监管建议调查。第二部分
Alfredo García-Arieta,Andrew Tam,Florencia Tiseyra et al.
Alfredo García-Arieta et al.
A biowaiver generally refers to the request to waive an in vivo bioequivalence study. A biowaiver may be granted not only based on the Biopharmaceutics Classifications System (BCS) but also for many immediate-release dosage forms based on p...
The need to redefine diabetic cardiomyopathy as a unique clinical entity that requires pharmacotherapy [0.03%]
糖尿病心肌病是一种需要药物治疗的独特临床实体,该疾病需重新定义
Alexa N King,John R Ussher
Alexa N King
Personalizing immunosuppressive therapy: predictors of drug switches in Malaysian kidney transplant recipients [0.03%]
马来西亚肾移植受者的免疫抑制治疗转换因素分析
Chiau Ling Choong,Farida Islahudin,Mohd Makmor-Bakry et al.
Chiau Ling Choong et al.
Objective: Tacrolimus-mycophenolic acid (MPA)-prednisolone immunosuppression remains the first-line management of kidney transplantation. Despite this, a switch to low-dose tacrolimus in combination with an mTOR inhibitor...
Corrigendum: Metabolic flux in macrophages in obesity and type-2 diabetes [0.03%]
肥胖和2型糖尿病中巨噬细胞的代谢通量の勘误公告
Angela Wong,Qiuyu Sun,Ismail Ibrahim Latif et al.
Angela Wong et al.
[This corrects the article DOI: 10.3389/jpps.2024.13210.]. Keywords: amino acids; fatty acids; glucose; keto...