Zhaolin Wang,H T Chen,Wilson Roa et al.
Zhaolin Wang et al.
Purpose: A nebulized aerosol formulation of the anti-cancer agent farnesol is developed and shown to induce cell death of human lung cancer cells in vitro. ...
Stephen Law,Weiqiu Wu
Stephen Law
Purpose: This paper evaluates a pilot project to determine the desirability of implementing a reimbursement model for pro-active interventions. A drug plan administration conducted an experiment in which a pharmacist coul...
Agatha W K Ng,Kishor M Wasan,Gabriel Lopez-Berestein
Agatha W K Ng
Purpose: The purpose of this review article is to review the development of a number of liposomal polyene antibiotics. Background: In t...
M K Chourasia,S K Jain
M K Chourasia
Purpose: Although oral delivery has become a widely accepted route of administration of therapeutic drugs, the gastrointestinal tract presents several formidable barriers to drug delivery. Colonic drug delivery has gained...
Co-encapsulation of two plasmids in chitosan microspheres as a non-viral gene delivery vehicle [0.03%]
Suna Ozbas-Turan,Cenk Aral,Levent Kabasakal et al.
Suna Ozbas-Turan et al.
Purpose: The aims of this study are to encapsulate two different plasmid DNAs (pGL2 and pMK3) in the same microsphere structure and to investigate in vivo transfection characteristics of chitosan microspheres. Furthermore...
Tanveer Ahmad Khan,Kok Khiang Peh
Tanveer Ahmad Khan
Purpose: To investigate the wound healing efficacy of two chitosan films, Chit-AA and Chit-LA, in comparison with a commercial preparation, Omiderm, using punch biopsy wounds in rats. ...
Rubinah K Chowdhary,Isha Shariff,David Dolphin
Rubinah K Chowdhary
Purpose: The purpose of this study was to examine the transfer of verteporfin (BPDMA) from its lipid based formulation to serum proteins. Methods: ...
Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model [0.03%]
Jean I Pachot,Roger P Botham,Klaus D Haegele et al.
Jean I Pachot et al.
Purpose: The aim of this study was to examine the transport mechanism of telithromycin in comparison with erythromycin, azithromycin, clarithromycin and roxithromycin. ...
Hydroxypropyl-beta-cyclodextrin-flutamide inclusion complex. II. Oral and intravenous pharmacokinetics of flutamide in the rat [0.03%]
2-羟丙基-B-环糊精-氟他胺包合物的口服和静脉给药动力学研究(英文)
Zhong Zuo,Yun K Tam,James Diakur et al.
Zhong Zuo et al.
Purpose: The objective of this work was to determine the pharmacokinetics of flutamide (FLT) and its active metabolite, 2-hydroxy-flutamide (FLT-2-OH) in rats, following formulation in hydroxypropyl-Beta-cyclodextrin (FLT...
Mathematical modelling of preparation of acyclovir liposomes: reverse phase evaporation method [0.03%]
阿昔洛韦脂质体反向蒸发法制备的数学模型研究
Avinash Kumar Seth,Ambikanandan Misra
Avinash Kumar Seth
Purpose: The aim of this study was to derive simple reduced second order polynomial equation for constructing contour plots to obtain predetermined % drug entrapment (PDE) within liposomes of acyclovir (ACY) when prepared...