HPLC determination of amoxicillin comparative bioavailability in healthy volunteers after a single dose administration [0.03%]
高效液相色谱测定健康志愿者单剂量给药后氨苄西林相对生物利用度的方法
Luis Renato Pires de Abreu,Rodrigo Mas Ortiz,Silvana Calafatti de Castro et al.
Luis Renato Pires de Abreu et al.
Purpose: An accurate, precise and sensitive HPLC assay was developed for the determination of amoxicillin in human plasma samples, to compare the bioavailability of two amoxicillin capsule (500mg) formulations (Amoxicilin...
Attenuation of benzodiazepine dependence in mice by a tri-substituted benzoflavone moiety of Passiflora incarnata Linneaus: a non-habit forming anxiolytic [0.03%]
紫藤属植物中三取代苯并黄酮类化合物可削弱苯二氮卓成瘾性：一种无致畸的抗焦虑成分
Kamaldeep Dhawan,Sanju Dhawan,Sumit Chhabra
Kamaldeep Dhawan
Purpose: A tri-substituted benzoflavone moiety (BZF) recently isolated from the methanol extract of aerial parts of the plant Passiflora incarnata Linneaus had exhibited encouraging results in countering the dependence pr...
Li Hui Zhen
Li Hui Zhen
Purpose: This article is used to give a brief overview for people who would like to submit a drug registration application in China, or for those who would like to get a broader international drug registration perspective...
Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat [0.03%]
选择性环氧合酶-1抑制剂SC-560的药动学、生物利用度及肾毒性的剂型依赖性研究（英文）
Xiao Wei Teng,Abdallalah K M Abu-Mellal,Neal M Davies
Xiao Wei Teng
Purpose: To delineate formulation dependent pharmacokinetics and bioavailability of SC-560, a relatively new cycloooxygenase-1 (COX-1) specific inhibitor, in the rat and examine its influence on the renal tubular enzyme, ...
Correlation of photosensitizer delivery to lipoproteins and efficacy in tumor and arthritis mouse models; comparison of lipid-based and Pluronic P123 formulations [0.03%]
光敏剂递送与脂蛋白的相关性及在肿瘤和关节炎小鼠模型中的疗效；基于lipid和Pluronic P123形式的比较研究
Rubinah K Chowdhary,Isha Sharif,Namrata Chansarkar et al.
Rubinah K Chowdhary et al.
Purpose: The purpose of this study was the use of animal models to demonstrate the importance of drug delivery (verteporfin) to plasma lipoproteins in order to attain efficacy of photodynamic therapy (PDT) in vivo. ...
Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats [0.03%]
聚氧乙烯-聚氧丙烯嵌段共聚物407对大鼠脂质代谢调节酶活性的影响
Kishor M Wasan,Ramaswamy Subramanian,Mona Kwong et al.
Kishor M Wasan et al.
Purpose: Recently, the P-407-treated mouse was established as a useful animal model of hyperlipidemia and atherosclerosis. The present study was aimed to determine whether P-407-induced hyperlipidemia in the rat is associ...
Zhaolin Wang,H T Chen,Wilson Roa et al.
Zhaolin Wang et al.
Purpose: A nebulized aerosol formulation of the anti-cancer agent farnesol is developed and shown to induce cell death of human lung cancer cells in vitro. ...
Stephen Law,Weiqiu Wu
Stephen Law
Purpose: This paper evaluates a pilot project to determine the desirability of implementing a reimbursement model for pro-active interventions. A drug plan administration conducted an experiment in which a pharmacist coul...
Agatha W K Ng,Kishor M Wasan,Gabriel Lopez-Berestein
Agatha W K Ng
Purpose: The purpose of this review article is to review the development of a number of liposomal polyene antibiotics. Background: In t...
M K Chourasia,S K Jain
M K Chourasia
Purpose: Although oral delivery has become a widely accepted route of administration of therapeutic drugs, the gastrointestinal tract presents several formidable barriers to drug delivery. Colonic drug delivery has gained...