Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea [0.03%]
阿戈美拉汀对阻塞性睡眠呼吸暂停患者的多导睡眠图参数的影响评估
Farzaneh Dastan,Behnaz Gholizadeh Niari,Parisa Adimi Naghan et al.
Farzaneh Dastan et al.
Purpose: Obstructive sleep apnea (OSA) is a common serious sleep disorder. Melatonin-based drugs such as agomelatine may have beneficial effects on patients with sleep disorders. This study aimed to evaluate agomelatine e...
Post-Marketing Safety of Vemurafenib: A Real-World Pharmacovigilance Study of the FDA Adverse Event Reporting System [0.03%]
Vemurafenib上市后安全性的研究：来自FDA不良事件报告系统的实际药物警戒研究
Yanxin Liu,Changjiang Dong,Xucheng He et al.
Yanxin Liu et al.
Purpose: Vemurafenib received approval for treatment of BRAF V600 variation metastatic melanoma in August 2011. This study analyzed Vemurafenib-related adverse events (AEs) to detect and characterize relevant safety signa...
Applications of Exhaled Breath Condensate Analysis for Drug Monitoring and Bioequivalence Study of Inhaled Drugs [0.03%]
呼吸冷凝液分析在吸入药物体内药物监测与生物等效性研究中的应用
Nastaran Hashemzadeh,Elaheh Rahimpour,Abolghasem Jouyban
Nastaran Hashemzadeh
The exhaled breath condensate (EBC) presents a simple and non-invasive alternative approach for bioequivalence assessments and therapeutic drug monitoring of inhaled drugs. EBC better represents the drug at the site of action and eliminates...
Analysis of Prednisolone-Induced Osteoporosis Using the Japanese Adverse Drug Event Report Database [0.03%]
使用日本药物不良事件报告数据库分析泼尼松龙引起的骨质疏松症
Wataru Wakabayashi,Mizuki Tanaka,Kiyoka Matsumoto et al.
Wataru Wakabayashi et al.
Purpose: Osteoporosis is an adverse event of prednisolone. This study aimed to assess prednisolone-induced osteoporosis (PIO) profiles and patient backgrounds by analyzing data from the Japanese Adverse Drug Event Report ...
A Review of Electronic Cigarettes and Liquid Nicotine Poisoning Exposure Cases in the United States [0.03%]
美国电子烟和液态尼古丁中毒曝光案例综述
Ayesha Ahmed
Ayesha Ahmed
Purpose: In 2007, electronic cigarettes (e-cigarette) were introduced as a smoking cessation device. Since then, its sale and marketing has been expanded annually. Concomitantly, there is an increase in the electronic cig...
Review of Pharmaceutical Applications of Diethylene Glycol Monoethyl Ether [0.03%]
二乙烯基乙醚在制药领域中的应用综述
Nastaran Hashemzadeh,Abolghasem Jouyban
Nastaran Hashemzadeh
Diethylene glycol monoethyl ether (DEGME) is a hydroalcoholic solvent that gained tremendous attention in the cosmetics, food, nanoformulations, and pharmaceutical industries. Due to its physicochemical features, it has been widely used as ...
A Survey of the Criteria Used for the Selection of Alternative Comparator Products by Participating Regulators and Organizations of the International Pharmaceutical Regulators Programme [0.03%]
国际药品监管项目参议组织选用对照药的评定标准调查研究报告
Andrew Tam,Alfredo Garcia-Arieta,Ivana Abalos et al.
Andrew Tam et al.
The safety and efficacy of a generic product are partly based on demonstrating bioequivalence to the innovator product; however, when the innovator product is no longer available as a comparator product, a survey conducted within the Bioequ...
Monkeypox: Virology, Pathophysiology, Clinical Characteristics, Epidemiology, Vaccines, Diagnosis, and Treatments [0.03%]
猴痘病毒学、病理生理、临床特征、流行病学、疫苗、诊断和治疗
Marzieh Soheili,Sherko Nasseri,Maryam Afraie et al.
Marzieh Soheili et al.
The World Health Organization, has declared the recent multiregional outbreak of monkeypox, a global public health emergency. Monkeypox is a zoonotic viral infection endemic to the west and central Africa. It belongs to the Poxviridae famil...
Helmut Schütz,Detlew Labes,Martin J Wolfsegger
Helmut Schütz
Purpose: More than a decade ago the option to assess highly variable drugs / drug products by reference-scaled average bioequivalence was introduced in regulatory practice. Recommended approaches differ between jurisdicti...
Efficacy and Safety of Anticoagulants for COVID-19 Patients in the Intensive Care Unit: A Systematic Review and Meta-Analysis [0.03%]
抗凝药物治疗重症监护病房中新冠肺炎患者的疗效和安全性：系统评价和 meta 分析
Yulistiani,Vina Neldi,Budi Suprapti et al.
Yulistiani et al.
Purpose: This study aims to analyze the efficacy and safety of anticoagulants for COVID-19 patients in the intensive care unit. Methods: ...