Rationale of a lower dexamethasone dose in prenatal congenital adrenal hyperplasia therapy based on pharmacokinetic modelling [0.03%]
基于药代动力学模型的先天性肾上腺增生产前治疗糖皮质激素地塞米松低剂量用药依据
Viktoria Stachanow,Uta Neumann,Oliver Blankenstein et al.
Viktoria Stachanow et al.
Context: Prenatal dexamethasone therapy is used in female foetuses with congenital adrenal hyperplasia to suppress androgen excess and prevent virilisation of the external genitalia. The traditional dexamethasone dose of ...
Oxytocin levels in response to pituitary provocation tests in healthy volunteers [0.03%]
健康志愿者垂体激发试验的催产素反应水平
Clara O Sailer,Bettina Winzeler,Sandrine A Urwyler et al.
Clara O Sailer et al.
Objective: Oxytocin, secreted into circulation through the posterior pituitary, regulates lactation, weight, and socio-behavioral functioning. Oxytocin deficiency has been suggested in patients with hypopituitarism; howev...
One year of the pandemic - how European endocrinologists responded to the crisis: a statement from the European Society of Endocrinology [0.03%]
疫情下的欧洲内分泌学会：来自欧洲内分泌学会的一年声明文档
A Giustina,M Marazuela,M Reincke et al.
A Giustina et al.
Changes that COVID-19 induced in endocrine daily practice as well as the role of endocrine and metabolic comorbidities in COVID-19 outcomes were among the striking features of this last year. The aim of this statement is to illustrate the m...
ENDOCRINE TUMOURS: Thyrotropin-secreting pituitary adenoma: a structured review of 535 adult cases [0.03%]
内分泌肿瘤：促甲状腺激素分泌垂体腺瘤的系统性回顾（535例成人患者的分析）
Carlien De Herdt,Eva Philipse,Christophe De Block
Carlien De Herdt
Background and aims: Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare entity, occurring in one per million people. We performed a systematic review of 535 adult cases summarizing the clinical, biochemical, ho...
25-OHD response to vitamin D supplementation in children: effect of dose but not GC haplotype [0.03%]
维生素D补充对儿童25-OHD的影响：剂量而不是GC基因型起了作用
Christine A Simpson,Jane H Zhang,Dirk Vanderschueren et al.
Christine A Simpson et al.
Objective: GC/DBP effects on response to vitamin D supplementation have not been well-studied. Thus we assessed free and total 25-OHD after vitamin D treatment across the six common GC haplotypes. ...
Randomized Controlled Trial
European journal of endocrinology. 2021 Jul 7;185(2):333-342. DOI:10.1530/EJE-21-0349 2021
IGF1 haploinsufficiency in children with short stature: a case series [0.03%]
儿童生长激素IGF-1单倍型不全导致身材矮小的病例报告系列研究
Willem Staels,Nuriya Alev,Isabelle Maystadt et al.
Willem Staels et al.
Context: Short stature in children is a common reason for referral to pediatric endocrinologists. The underlying cause of short stature remains unclear in many cases and patients often receive unsatisfactory, descriptive ...
'You cannot expect miracles to happen overnight': patience pays off when you wish to establish a new adrenocortical carcinoma cell line [0.03%]
耐心才能有所收获：建立新的肾上腺皮质癌细胞系并非一日之功
Enzo Lalli
Enzo Lalli
Growing attention is being paid to the association of adrenocortical carcinoma (ACC), a rare endocrine malignancy, to cancer predisposition syndromes caused by germline mutations in genes involved in the control of genome stability. Tumour ...
Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls [0.03%]
接受胰岛素治疗的2型糖尿病患者和对照组中急性低血糖与心律失常的关系
Andreas Andersen,Jonatan I Bagger,Maria P A Baldassarre et al.
Andreas Andersen et al.
Objective: Hypoglycemia is associated with an increased risk of cardiovascular disease including cardiac arrhythmias. We investigated the effect of hypoglycemia in the setting of acute glycemic fluctuations on cardiac rhy...
Characteristics and treatment responsiveness of patients with acromegaly and a paradoxical GH increase to oral glucose load [0.03%]
口服葡萄糖负荷后生长激素反常增加的肢端肥大症患者的临床特征和治疗反应分析
Virginie Atquet,Orsalia Alexopoulou,Dominique Maiter
Virginie Atquet
Objectives: We aimed to investigate the clinical, biochemical, histological and radiological characteristics as well as the response to somatostatin analogs (SSA) in a large cohort of acromegaly patients with a paradoxica...
Sex disparities in COVID-19 outcomes of inpatients with diabetes: insights from the CORONADO study [0.03%]
糖尿病住院患者的性别差异对新冠肺炎的预后影响——来自CORONADO研究的新见解
Blandine Tramunt,Sarra Smati,Sandrine Coudol et al.
Blandine Tramunt et al.
Objective: Male sex is one of the determinants of severe coronavirus diseas-e-2019 (COVID-19). We aimed to characterize sex differences in severe outcomes in adults with diabetes hospitalized for COVID-19. ...
Observational Study
European journal of endocrinology. 2021 Jul 5;185(2):299-311. DOI:10.1530/EJE-21-0068 2021