Radiology-based artificial intelligence for predicting targeted therapy response in pan-cancer: a comprehensive review [0.03%]
基于放射学的人工智能在泛癌靶向治疗反应预测中的应用：综述
Bo Yang,Silin Chen,Yunze Wang et al.
Bo Yang et al.
Background: Targeted therapy is central to precision oncology, but identifying patients who will benefit remains challenging. Conventional molecular testing, though the current standard, provides limited predictive value....
Development of a cancer metastasis-associated risk model via multi-machine-learning algorithms for prognostic risk evaluation and clinical application in oral squamous cell carcinoma [0.03%]
基于多机器学习算法的癌症转移相关风险模型的发展用于口腔鳞状细胞癌预后风险评估及临床应用
Xu Han,Tiantian Sun,Yuanyuan Dai et al.
Xu Han et al.
Background: Oral squamous cell carcinoma (OSCC) represents a highly malignant form of cancer characterized by molecular heterogeneity and unsatisfactory treatment outcomes, with approximately 50% of patients experiencing ...
Urinary metabolome at birth in patients with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia and long-term neurodevelopmental outcomes: a 7-year follow up [0.03%]
出生时患有缺氧缺血性脑病并接受治疗性低温患者的尿代谢组和长期神经发育结局：七年随访研究
Claudio Ancona,Enrico Valerio,Nicoletta Mainini et al.
Claudio Ancona et al.
Background: Hypoxic-ischemic encephalopathy (HIE) is a leading cause of neonatal mortality and morbidity, yet no validated biomarkers currently exist to predict long-term outcomes. We investigated the potential of the neo...
Should routine HPV vaccination programs include males 25-29 years? A systematic review and global meta-analysis [0.03%]
应将常规HPV疫苗接种计划扩大至25-29岁男性吗？系统评价和全球性荟萃分析
Siran Wan,Shunhong Zhang,Saidi Hu et al.
Siran Wan et al.
Background: Males aged 25-29 years represent the peak transmission group for human papillomavirus (HPV). However, they are often excluded from routine vaccination programs due to concerns regarding cost-effectiveness and ...
Galvanic vestibular stimulation promotes visuospatial cognitive recovery in acute unilateral vestibulopathy via targeted neural modulation: a randomized controlled trial [0.03%]
电耳石刺激通过靶向神经调控促进急性单侧迷路病变的视觉空间认知恢复：一项随机对照试验
Sun-Young Oh,Thanh Tin Nguyen,Jin-Ju Kang et al.
Sun-Young Oh et al.
Background: The vestibular system plays a crucial role in spatial orientation and hippocampal-dependent memory. While bilateral vestibular loss is known to impair spatial cognition, recent evidence highlights that even un...
Randomized Controlled Trial
Journal of translational medicine. 2025 Nov 24;23(1):991. DOI:10.1186/s12967-025-07036-7 2025
A robust classifier for the intrinsic consensus molecular subtypes in colorectal cancer [0.03%]
用于结直肠癌固有共识分子亚型的稳健分类器
Petros Tsantoulis,Yourae Hong,Pratyaksha Wirapati et al.
Petros Tsantoulis et al.
The CLIC1-PKM2 axis orchestrates glycolytic metabolism to accelerate gastric cancer progression [0.03%]
CLIC1-PKM2轴调控糖酵解代谢以促进胃癌进展
Jian Yang,Zhu Yu,Yue Feng et al.
Jian Yang et al.
Background: Metabolic reprogramming is a hallmark of malignant transformation and supports tumor proliferation and survival. Chloride intracellular channel protein 1 (CLIC1) has been implicated in multiple oncogenic proce...
NSUN7-mediated m5C modification of circNTRK2 regulates stemness properties of glioblastoma cells by activating STK31 [0.03%]
circNTRK2的m5C修饰调控胶质母细胞瘤干细胞样特性的作用及机制研究
Yubo Zhao,Mengyang Zhang,Jiachun Ma et al.
Yubo Zhao et al.
Fat-brain axis indicated by mutual impacts between body fat and brain phenotypes [0.03%]
脂肪-大脑轴：体脂和大脑表型相互作用所致
Ancha Baranova,Li Fu,Qian Zhao et al.
Ancha Baranova et al.
The hepatic macrophage: a key regulator of liver metastatic tumor microenvironment through cell crosstalk [0.03%]
肝巨噬细胞通过细胞通讯调控肝脏转移性肿瘤微环境的关键调节者
Weihua Wang,Ziying Yi,Zeyu Yang et al.
Weihua Wang et al.
Liver metastasis continues to be a leading cause of cancer-related mortality, particularly in colorectal, pancreatic, and breast cancer. The successful establishment of metastatic lesions depends critically on the liver metastatic tumor mic...