Mona Peyman,Anna Babin-Ebell,Rosalía Rodríguez-Rodríguez et al.
Mona Peyman et al.
Background: Endoplasmic reticulum (ER) stress-mediated increases in the hepatic levels of the very low-density lipoprotein (VLDL) receptor (VLDLR) promote hepatic steatosis by increasing the delivery of triglyceride-rich ...
Diverse roles of SARS-CoV-2 Spike and Nucleocapsid proteins in EndMT stimulation through the TGF-β-MRTF axis inhibited by aspirin [0.03%]
阿司匹林通过TGF-β-MRTF轴抑制SARS-CoV-2刺突和核衣壳蛋白在内皮-间质转化中的多种作用
Wojciech M Ciszewski,Lucyna A Woźniak,Katarzyna Sobierajska
Wojciech M Ciszewski
Background: The SARS-CoV-2 virus causes severe COVID-19 in one-fifth of patients. In addition to high mortality, infection may induce respiratory failure and cardiovascular complications associated with inflammation. Acut...
Xingrui Mu,Rifang Gu,Ming Tang et al.
Xingrui Mu et al.
Chronic wounds, resulting from persistent inflammation, can trigger a cascade of detrimental effects including exacerbating inflammatory cytokines, compromised blood circulation at the wound site, elevation of white blood cell count, increa...
Influence of intersignaling crosstalk on the intracellular localization of YAP/TAZ in lung cells [0.03%]
细胞间信号串扰对肺细胞内YAP/TAZ定位的影响
I A Govorova,S Y Nikitochkina,E A Vorotelyak
I A Govorova
A cell is a dynamic system in which various processes occur simultaneously. In particular, intra- and intercellular signaling pathway crosstalk has a significant impact on a cell's life cycle, differentiation, proliferation, growth, regener...
Endothelial cell-derived extracellular vesicles modulate the therapeutic efficacy of mesenchymal stem cells through IDH2/TET pathway in ARDS [0.03%]
内皮细胞来源的细胞外囊泡通过IDH2 / TET通路调节间充质干细胞在ARDS中的治疗效应
Xiao Wu,Ying Tang,Xinxing Lu et al.
Xiao Wu et al.
Background: Acute respiratory distress syndrome (ARDS) is a severe and fatal disease. Although mesenchymal stem cell (MSC)-based therapy has shown remarkable efficacy in treating ARDS in animal experiments, clinical outco...
Megakaryocytic IGF1 coordinates activation and ferroptosis to safeguard hematopoietic stem cell regeneration after radiation injury [0.03%]
巨核细胞IGF1调控激活和铁死亡以保护辐射损伤后的造血干细胞再生
Weinian Liao,Xinliang Chen,Shuzhen Zhang et al.
Weinian Liao et al.
Background: Hematopoietic stem cell (HSC) regeneration underlies hematopoietic recovery from myelosuppression, which is a life-threatening side effect of cytotoxicity. HSC niche is profoundly disrupted after myelosuppress...
All-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury [0.03%]
全反式维甲酸预处理间充质干细胞可增强对急性肾损伤的治疗作用
Yifan Zhang,Xiaochen Wang,Yuwei Ji et al.
Yifan Zhang et al.
A promising new therapy option for acute kidney injury (AKI) is mesenchymal stem cells (MSCs). However, there are several limitations to the use of MSCs, such as low rates of survival, limited homing capacity, and unclear differentiation. I...
Xuebin Zhou,Liangliang Zhao,Chenguang Wang et al.
Xuebin Zhou et al.
The Crumbs protein (CRB) family plays a crucial role in maintaining the apical-basal polarity and integrity of embryonic epithelia. The family comprises different isoforms in different animals and possesses diverse structural, localization,...
Correction: The development of probiotics and prebiotics therapy to ulcerative colitis: a therapy that has gained considerable momentum [0.03%]
关于益生菌和益生元治疗溃疡性结肠炎的发展：一种已经获得巨大动力的疗法（纠错）
Jing Guo,Liping Li,Yue Cai et al.
Jing Guo et al.
Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis [0.03%]
含MFGE8的结直肠癌细胞外囊泡促进巨噬细胞efferocytosis
Zhixin Ma,Yu Sun,Yang Yu et al.
Zhixin Ma et al.
Background: Colorectal cancer (CRC) commonly exhibits tolerance to cisplatin treatment, but the underlying mechanisms remain unclear. Within the tumor microenvironment, macrophages play a role in resisting the cytotoxic e...