Therapeutic potential of Urtica urens L. extract: phytochemical characterization and evaluation of antioxidant and antiproliferative properties [0.03%]
刺梧桐提取物的治疗潜力：植物化学表征及其抗氧化和抗增殖特性的评估
Hamza Kemchache,Hanane Khither,Khalil Kaouane et al.
Hamza Kemchache et al.
Urtica urens L. (Urticaceae) is a traditional medicinal plant widely used in ethnopharmacology for its pharmacological properties. This study aimed to investigate the LC-MS/MS phenolic profile, antioxidant activity, and cytotoxic potential ...
Synthesis and antiproliferative evaluation of L-amino acid-6-gliotoxin ester trifluoroacetates [0.03%]
L-氨基酸-6-白念珠菌毒素酯三氟乙酸盐的合成及抗增殖活性评估
Xue An,Kexin Lin,Lihong Shan
Xue An
This study aimed to develop gliotoxin derivatives with high yield and low toxicity through fermentation optimisation and structural modification. First, the culture conditions were optimised, resulting in a yield of 208 mg L-1. Subsequently...
Unveiling tullasnellachromone: a novel anti-bacterial and anti-tumor chromone of endophytic fungus Tullasnella sp. from Dendrobium wangliangii [0.03%]
隐于石斛中内生真菌Tullasnella sp.的新抗菌和抗肿瘤化合物Tullasnellachromone的发现与研究
Yuehui Liu,Senyao Cui,Wei Xiong et al.
Yuehui Liu et al.
This research isolated and identified tullasnellachromone (1), one novel chromone derivative, together with eleven known compounds (2-12) were isolated from the endophytic fungus Tullasnella sp. of Dendrobium wangliangii. These isolates wer...
Pharmacodynamics and mechanisms of triterpene components from the leaves of Astragalus mongholicus Bunge in the treatment of Alzheimer's disease [0.03%]
蒙古黄芪叶三萜类成分治疗阿尔茨海默病的药理学及机制研究
Lei Bao,Fuxia Zhao,Wenxiang Xu et al.
Lei Bao et al.
This study investigates the therapeutic potential and underlying mechanisms of triterpenoids (TR) derived from the leaves of Astragalus mongholicus Bunge for the treatment of Alzheimer's disease (AD). Eighteen triterpenoid compounds were id...
Otoprotective effects of a new polyketide isolated from the mangrove endophytic fungus Diaporthe pseudomangiferae [0.03%]
从红树内生真菌Diaporthe pseudomangiferae中分离的一种新的聚酮类化合物的器官保护作用
Leshi Yu,Le Gao,Hongfen Tan et al.
Leshi Yu et al.
One novel polyketide compound (1) and eight known compounds (2-9) were isolated from the mangrove endophytic fungus Diaporthe pseudomangiferae. Their structures were identified by spectroscopic analysis, including nuclear magnetic resonance...
Toxicity assessment of Mitragyna speciosa leaf extracts using zebrafish (Danio rerio) embryos and analysis of their Q-TOF LCMS chemical profiles [0.03%]
采用斑马鱼(zebrafish)胚胎评估Mitragyna speciosa叶提取物的毒性及其Q-TOF LCMS化学谱型分析
Taslima Begum,Qamar Uddin Ahmed,Mohd Hafiz Arzmi et al.
Taslima Begum et al.
Mitragyna speciosa has been traditionally used in Southeast Asia to treat various health conditions. This study evaluated the toxicity of leaf extracts obtained using 100% methanol through maceration (100%M) and ultrasonic-assisted (100%U) ...
Antibacterial compounds from an endophytic fungus Cladosporium colombiae GTJ67 [0.03%]
内生真菌Cladosporium colombiae GTJ67的抗菌化合物研究
Hua-Juan Yang,Yan Shu,Yan Luo et al.
Hua-Juan Yang et al.
An undescribed cladosporol derivative named cladosporine (1), together with eight known compounds (2-9) were characterised from Cladosporium colombiae GTJ67, an endophytic fungus from Aconitum hemsleyanum. Their structures were established ...
Nanoemulsion advancements for effective Sargassum serratifolium delivery in cosmetics: extraction, characterisation, and molecular docking [0.03%]
用于化妆品中的海洋褐藻梯丽叶海黍有效递送的纳米乳液技术：提取、表征和分子对接研究
Sonita A P Siboro,Sabrina Aufar Salma,Frita Yuliati et al.
Sonita A P Siboro et al.
In the cosmetic industry, active ingredients often consist of organic compounds that are hydrophobic, making oil-based formulations impractical. Oil-in-water (O/W) nanoemulsions are used to deliver such ingredients in an aqueous medium. How...
Metabolic profiling and biological studies of Aegle marmelos enriched fractions: a potential source for pharmaceuticals and nutraceuticals [0.03%]
以印楝马梅洛斯 enrichment 分数的小生境代谢轮廓和生物研究：药物和营养补充剂的潜在来源
Ritu Tiwari,Smita Mishra,Gnanabhaskar Dababoina et al.
Ritu Tiwari et al.
Background: Aegle marmelos exhibits a diverse spectrum of primary and secondary metabolites with significant therapeutic potential. This study explains a systematic protocol for a comprehensive -assessment of bioactivity,...
Cytotoxic investigation of new compounds from a poisonous consumable mushroom Sarcosphaera coronaria (Jacq.) J. Schröt. (Syn: sarcosphaera crassa (Santi) Pouzar) [0.03%]
毒蘑菇Sarcosphaera coronaria中的新型细胞毒性化合物研究（Sarcosphaera coronaria (Jacq.) J. Schröter，又名sarcosphaera crassa (Santi) Pouzar）
Zain Ullah,Mehmet Ozturk,Zhao Ting et al.
Zain Ullah et al.
Sarcosphaera coronaria, a poisonous mushroom safe for consumption when cooked properly, was investigated for cytotoxic metabolites against HeLa (cervical), HT-29 (adenocarcinoma), and MCF-7 (breast) cancer cell lines. Polarity-based extract...