Bioguided phytochemical evaluation of the antiproliferative activity of the ethanolic extract of Skytanthus acutus, an extremophile plant from northern Chile [0.03%]
用于评估智利北部极端环境植物Skytanthus acutus乙醇提取物抗增殖活性的导向植物化学研究
Arrieche Dioni,Javier Pardo-Baeza,José J Fernández et al.
Arrieche Dioni et al.
Skytanthus acutus Meyen (Apocynaceae), commonly known as 'Cuerno de cabra,' is an endemic species from northern Chile that grows in dune and desert habitats of the Atacama region. This study evaluated the antiproliferative activity of an et...
Study on the extraction, purification and anti-ageing activity of polydatin in Reynoutria japonica Houtt [0.03%]
日本 knotweed 中白藜芦醇苷的提取、纯化及其抗衰老作用研究
Simin Yang,Xiaotong Qin,Mingwei Jia et al.
Simin Yang et al.
This study optimised the extraction and purification of polydatin from Reynoutria japonica Houtt. and evaluated its anti-ageing activity. Microwave-assisted enzymatic extraction (MAEE) was employed, achieving a maximum polydatin content of ...
Betulinic acid derivatives in melanoma therapy: pharmacological assessment in a preclinical approach [0.03%]
白桦酸衍生物在黑色素瘤治疗中的药理评估：一种临床前方法
Elenilson Figueiredo da Silva,Jessica Gotardi,Artur Stramari de Vargas et al.
Elenilson Figueiredo da Silva et al.
Melanoma is the deadliest form of skin cancer owing to its metastatic potential. In this study, the anticancer effects of Betulinic Acid (BA) derivatives were evaluated in melanoma models. The in vitro cytotoxic effect on B16-F10 (melanoma)...
Lignanamides, alkaloids, and other constituents from stems of Tinospora crispa [0.03%]
Tinospora crispa茎的倍半萜内酰胺、生物碱及其他成分分离鉴定研究
Yi-Yang Yuan,Xiang-Hong Chen,Tian Gao et al.
Yi-Yang Yuan et al.
A phytochemical investigation of stems of Tinospora crispa was carried out and two pairs of novel regioisomeric lignanamides, tinosporamides A-D (1-4), were isolated along with ten known alkaloids and one known phaeophytin. The chemical str...
Computational exploration of Aegle marmelos coumarins: DFT, molecular docking, and dynamics studies for anti-hypertensive activity [0.03%]
贝诺花香豆素抗高血压活性的计算研究：DFT、分子对接及动力学研究
Jan Alam,Muhammad Ali Versiani,Nadeem Ahmed et al.
Jan Alam et al.
Literature reviews indicate that Aegle marmelos exhibits significant anti-hypertensive activity. Therefore, the present study is focused on the isolation and identification of bioactive compounds responsible for this effect. Purification of...
Pyranobutflavin: a butoxy-bridged pyranone-flavonoid hybrid from baicalin, and its anti-hepatocellular carcinoma activity [0.03%]
拜因酸衍生物吡喃咲酮 flavonoid 杂化物_PYF 的合成及其抗肝癌细胞活性研究
Jiali Shao,Weifeng Zhang,Lingling Tang et al.
Jiali Shao et al.
A butoxy-bridged pyranone-flavonoid hybrid, pyranobutflavin, together with two known compounds (baicalein and baicalin butyl ester), was obtained after high-temperature-little-acid hydrolysis of baicalin naturally occurring in the roots of ...
Two new abietane-type diterpenoids from the roots of Tripterygium wilfordii Hook.f. and their diacylglycerol acyltransferase activity [0.03%]
两种Tripterygium wilfordii中的倍半萜二聚体茋类生物碱及其DGAT酶活性研究
Hao Xu,Xue-Feng Wu,Ying-Xiao Xiao et al.
Hao Xu et al.
Two new abietane-type diterpenoids, triptoquinone G (1) and (5S,10S)-triptonoterpene (2), along with four known diterpenoids (3 - 6), were isolated from the seeds of Tripterygium wilfordii Hook.f. Their structures were elucidated based on e...
Chemical components from Uncaria gambir (W.Hunter) Roxb. and their preliminary bioactivities in CDC25B phosphatase inhibition and vasodilatory activity [0.03%]
Uncaria gambir (W.Hunter) Roxb.的化学成分及其CDC25B磷酸酶抑制和血管舒张活性研究
Wenyan Liu,Song Jin,Ziming Wang et al.
Wenyan Liu et al.
The endangered Uncaria gambir (W.Hunter) Roxb. (U. gambir) remains largely unexplored in chemical constituents and bioactivities. Therefore, fifteen compounds (1-15), comprising monoterpene indole alkaloids, lignans, flavonoids, triterpenoi...
Sesquiterpene-rich n-hexane extracts from Aspidosperma subincanum Mart.: anti- Xanthomonas citri activity, acetylcholinesterase inhibition and insights into molecular docking [0.03%]
阿スピ多スペル玛种子_incana_的富含倍半萜类的己烷提取物：抗_Xanthomonas citri_活性，乙酰胆碱酯酶抑制及分子对接研究
Hindenburg C G da Costa,Jaciel G Dos Santos,Cassia C Fernandes et al.
Hindenburg C G da Costa et al.
Although Aspidosperma subincanum Mart. is traditionally used for metabolic and digestive disorders, its volatile nonpolar fraction remains unexplored. This study investigated n-hexane extracts from leaves (HE-GL) and stem bark (HE-GS), targ...
Anti-obesity potential of Elaeagnus angustifolia L. associated with phenolic profiles determined by LC-qTOF-MS [0.03%]
采用LC-qTOF-MS测定牻牛儿苗素 profiles确定的胡枝子抗肥胖潜力
Aslı Can Ağca,Tuba Reçber,Emirhan Nemutlu et al.
Aslı Can Ağca et al.
Obesity significantly impairs quality of life through physical and psychological effects, requiring effective therapeutic strategies. This study is the first to investigate the anti-obesity potential of different organs of Elaeagnus angusti...