Micro-computed tomographical and histopathological analyses of medial tibial plateaus from patients with subchondral insufficiency fracture or osteoarthritis of the knee [0.03%]
膝关节骨下骨梗死性骨折或骨关节炎患者的内侧胫骨平台的微CT和组织病理学分析
Takuya Yamamura,Jun Tomura,Haruka Kaneko et al.
Takuya Yamamura et al.
Background: Subchondral insufficiency fracture of the knee (SIFK) is a rare and rapidly progressing knee joint disease. The typical diagnostic finding of SIFK by magnetic resonance imaging (MRI) is a subchondral hypointen...
FSCN1 induces subchondral bone sclerosis in osteoarthritis via modulating actin cytoskeleton dynamics and YAP signaling [0.03%]
FSCN1通过调节肌动蛋白细胞骨架动力学和YAP信号通路诱导骨关节炎中的软骨下骨硬化
Yun Xiao,Liangyu Chen,Dalin Chen et al.
Yun Xiao et al.
Background: Subchondral bone is a dynamic tissue maintained by bone remodeling and responded rapidly to mechanical loading, which is strongly associated with cartilage degradation in osteoarthritis (OA), but the underlyin...
Interleukin-6 blockade modulates monocyte recruitment to protect against diastolic dysfunction associated with inflammatory arthritis [0.03%]
抗白细胞介素-6治疗可调节单核细胞募集以防止与炎性关节炎相关的舒张功能障碍
Marilena Christoforou,Jianmin Chen,Dianne Cooper et al.
Marilena Christoforou et al.
Background: There is an unmet clinical need to manage heart failure with preserved ejection fraction in people with rheumatoid arthritis (RA). One hurdle is the absence of preclinical models to study pathology and pharmac...
Microvascular imaging is superior to power doppler in synovitis vascular flow detection in rheumatoid arthritis using the OMERACT-EULAR scoring system [0.03%]
在类风湿关节炎滑膜炎微血管检测中,微血管成像技术优于能量多普勒成像技术：基于OMERACT-EULAR评分系统的研究
João Madruga Dias,Marcos Cerqueira,Diogo Esperança Almeida et al.
João Madruga Dias et al.
Introduction: Superb Microvascular Imaging (SMI) uses an adaptive algorithm that improves the visualization of vessels with low-velocity blood flow. Power Doppler (PD) imaging is routinely used in clinical practice but in...
Development of a confidence-based Natural Language Processing tool to identify inflammatory arthritis from non-inflammatory conditions in Rheumatology medical notes [0.03%]
开发基于自信的自然语言处理工具以根据风湿病医疗记录识别炎性关节炎和非炎性条件
Antonio Tonutti,Nicoletta Luciano,Benedetta Maizza et al.
Antonio Tonutti et al.
Soluble CD13 in systemic sclerosis: clinical observations and transcriptomic insights from peripheral blood [0.03%]
系统性硬化症中的可溶型CD13:外周血的临床观察和转录组学见解
Yuzo Ikari,Chenyang Lu,Alyssa Rosek et al.
Yuzo Ikari et al.
Sex differences in pain-related biopsychosocial assessments in patients with axial spondyloarthritis [0.03%]
轴性脊柱关节炎患者的疼痛相关生物心理社会评估的性别差异
Yvonne Maria van der Kraan,Davy Paap,Hans Timmerman et al.
Yvonne Maria van der Kraan et al.
Development of a scoring system to assist clinicians in the early referral of patients with suspected juvenile idiopathic arthritis: the EasyJIA score [0.03%]
易早诊早治幼年特发性关节炎评分系统的发展：EasyJIA评分
Achille Marino,Carlo Alberto Scirè,Paola Baldassarre et al.
Achille Marino et al.
Objective: Juvenile idiopathic arthritis (JIA) is the most common chronic pediatric rheumatic disease. Early referral to a specialized center is crucial for prompt diagnosis and treatment. This study aims to develop and v...
Gender differences in the clinical features and quality of life of Japanese patients with systemic lupus erythematosus: a cross-sectional study based on the LUNA registry [0.03%]
日本系统性红斑狼疮患者临床特征及生活质量的性别差异——LUNA注册登记库的横断面分析
Yuya Sumichika,Honoka Ebina,Shuzo Sato et al.
Yuya Sumichika et al.
Background: Gender differences in clinical manifestations and disease progression of systemic lupus erythematosus (SLE) have been well documented; however, there is a paucity of literature on the gender differences in the...
Real-world comparative effectiveness of sarilumab versus Janus kinase inhibitors as monotherapy in rheumatoid arthritis [0.03%]
托法替布单药治疗风湿性关节炎的疗效及与沙利鲁马单药治疗疗效的真实世界对比研究
Yuji Nozaki,Kazuya Kishimoto,Tetsu Itami et al.
Yuji Nozaki et al.
Background: Sarilumab (SAR), an interleukin-6 receptor inhibitor (IL-6Ri), and Janus kinase inhibitors (JAKi) are approved options for rheumatoid arthritis (RA) when methotrexate (MTX) cannot be used. Real-world evidence ...