Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome [0.03%]
肌炎和抗合成酶综合征患者队列中抗Jo-1自身抗体的纵向评估：对不同组氨tRNA合成酶结构域和剪接变体的反应性和亲和力谱分析
Antonella Notarnicola,Charlotta Preger,Susanna L Lundström et al.
Antonella Notarnicola et al.
Background: To address the reactivity and affinity against histidyl-transfer RNA synthetase (HisRS) autoantigen of anti-Jo1 autoantibodies from serum and bronchoalveolar lavage fluid (BALF) in patients with idiopathic inf...
Preferable outcome of Janus kinase inhibitors for a group of difficult-to-treat rheumatoid arthritis patients: from the FIRST Registry [0.03%]
中国难治性类风湿关节炎患者JAK抑制剂的优选方案：来氟 Registry研究
Sae Ochi,Koshiro Sonomoto,Shingo Nakayamada et al.
Sae Ochi et al.
Backgrounds: Treatment of difficult-to-treat rheumatoid arthritis (D2T RA) is one of the greatest unmet needs in rheumatology. This study aims to find out preferable treatment options for a group of D2T RA patients who ar...
Association between perinatal factors and future risk for gout-a nested case-control study [0.03%]
围生期因素与未来痛风风险的关联-一项病例对照研究
Mats Dehlin,Lennart T H Jacobsson
Mats Dehlin
Background: Increased level of urate is the strongest risk factor for gout development but since only a minority of hyperuricemics are affected by gout, other pathogenic factors must be considered. Low birth weight is ass...
Senescent skeletal cells cross-talk with synovial cells plays a key role in the pathogenesis of osteoarthritis [0.03%]
衰老的骨骼细胞与滑膜细胞的相互作用在骨关节炎发病机制中起关键作用
Chong-Jie Wu,Ri-Xu Liu,Song-Wei Huan et al.
Chong-Jie Wu et al.
Osteoarthritis (OA) has been recognized as an age-related degenerative disease commonly seen in the elderly that affects the whole "organ" including cartilage, subchondral bone, synovium, and muscles. An increasing number of studies have su...
Plasma interleukin-23 and circulating IL-17A+IFNγ+ ex-Th17 cells predict opposing outcomes of anti-TNF therapy in rheumatoid arthritis [0.03%]
抗TNF治疗中血浆IL-23和循环IL-17A+IFNγ+ ex-Th17细胞预示着对立的疗效：在类风湿关节炎中的研究
Melanie J Millier,Niamh C Fanning,Christopher Frampton et al.
Melanie J Millier et al.
Objectives: TNF-α inhibitors are widely used in rheumatoid arthritis (RA) with varying success. Response to TNF-α inhibition may reflect the evolution of rheumatoid inflammation through fluctuating stages of TNF-α depe...
Clinical features of gout in adult patients with type Ia glycogen storage disease: a single-centre retrospective study and a review of literature [0.03%]
I型糖原贮积病成人患者痛风的临床特征：单中心回顾性研究及文献复习
Na Xu,Xinxin Han,Yun Zhang et al.
Na Xu et al.
Background: This study aimed to explore the clinical features of gout in adult patients with glycogen storage disease type Ia (GSD Ia). Methods: ...
Rheumatoid arthritis, as a clinical disease, but not rheumatoid arthritis-associated autoimmunity, is linked to cardiovascular events [0.03%]
风湿性关节炎作为一种临床疾病，但不是与风湿性关节炎相关的自身免疫病，会引发心血管事件
Hélène Gouze,Philippe Aegerter,Roula Said-Nahal et al.
Hélène Gouze et al.
Background: Rheumatoid arthritis (RA) is characterized by increased cardiovascular (CV) mortality. CV events are particularly high in patients with RA-specific autoimmunity, including rheumatoid factor (RF) and anti-citru...
Analysis of the fecal and oral microbiota in chronic recurrent multifocal osteomyelitis [0.03%]
慢性复发性多灶性骨髓炎患者粪便及口腔菌群分析
Philipp Rausch,Meike Hartmann,John F Baines et al.
Philipp Rausch et al.
Background: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoinflammatory bone disease for which a lack of bacterial involvement is a key diagnostic feature to distinguish it from other symptomatically rela...
Systematic review of quantitative preference studies of treatments for rheumatoid arthritis among patients and at-risk populations [0.03%]
关于类风湿关节炎患者和高危人群治疗方案偏好的定量研究的系统评价
Gwenda Simons,Joshua Caplan,Rachael L DiSantostefano et al.
Gwenda Simons et al.
Treatments used for rheumatoid arthritis (RA) are under investigation for their efficacy to prevent RA in at risk groups. It is therefore important to understand treatment preferences of those at risk. We systematically reviewed quantitativ...
Factors affecting patient satisfaction related to cost and treatment effectiveness in rheumatoid arthritis: results from the multicenter observational cohort study, FRANK Registry [0.03%]
影响类风湿关节炎患者的费用和治疗效果的相关因素：来自多中心观察性队列研究FRANK registry的结果
Toshifumi Fujiwara,Masakazu Kondo,Hisakata Yamada et al.
Toshifumi Fujiwara et al.
Background: To further improve rheumatoid arthritis (RA) treatment, it is necessary to understand each RA patient's satisfaction and to identify the factors affecting their satisfaction. Despite the rise in medical costs ...
Observational Study
Arthritis research & therapy. 2022 Feb 22;24(1):53. DOI:10.1186/s13075-022-02746-5 2022