Machine Learning Prediction of 90-Day Mortality in HBV-Related ACLF Using Olink-Derived Inflammatory Protein Signatures [0.03%]
基于Olink检测炎性因子谱型的HBV相关ACLF患者90天死亡预测模型建立及验证
Yi Zhang,Lina Sun,Huimin Liu et al.
Yi Zhang et al.
Background: Hepatitis B virus-induced acute-on-chronic liver failure (HBV-ACLF) has extremely high mortality rates and is closely linked to inflammatory responses. Early interventions in high-risk patients can significant...
Sex-Specific Differences and a Predictive Model Based on Clinical and Biochemical Parameters for Minimal Hepatic Encephalopathy [0.03%]
基于临床和生化参数的轻微肝性脑病预测模型及性别差异研究
Juan José Gallego,Franc Casanova-Ferrer,Alessandra Fiorillo et al.
Juan José Gallego et al.
Background and aims: Minimal hepatic encephalopathy (MHE) affects 30%-40% of cirrhotic patients, showing cognitive and motor impairment, and affecting quality of life. MHE represents the earliest stage of hepatic encephal...
Updated Reference Limits for Liver Blood Tests With Validation Against Long-Term Liver-Related Outcomes [0.03%]
基于长期肝脏预后的肝功能血清学指标参考值的更新与验证
Fredrik Åberg,Antti Jula,Veikko Salomaa et al.
Fredrik Åberg et al.
Background and aims: Liver blood tests are widely used, but their reference limits may not reliably predict long-term liver-related risks. Previous studies to establish reference limits often lacked rigorous exclusion of ...
Future Research Considerations on TMPRSS6 as a Therapeutic Target for MASLD [0.03%]
有关TMPRSS6作为MASLD治疗靶点的未来研究方向考虑
Zongyu Yang,Songjie Liao
Zongyu Yang
GLP-1RA and Liver Fibrosis Progression in MASLD and Type 2 Diabetes: Target Trial Emulation Using Propensity Score Matching [0.03%]
基于倾向性评分匹配的靶标试验模拟评估胰高血糖素样肽-1受体激动剂对MASLD和2型糖尿病患者肝纤维化进展的影响
Jonggi Choi,Tushar Kamath,Vy H Nguyen et al.
Jonggi Choi et al.
Background and aims: GLP-1 receptor agonists (GLP-1RA) are widely used in type 2 diabetes mellitus (T2DM) and may confer hepatoprotective effects in metabolic dysfunction-associated steatotic liver disease (MASLD). Their ...
Comparable 5-Year Survival in People With and Without HIV Following Hepatocellular Carcinoma Diagnosis: A Multicenter Study [0.03%]
人类免疫缺陷病毒(HIV)感染者和非感染者诊断肝细胞癌后的五年生存率多中心研究
Massimo Iavarone,Eleonora Alimenti,Massimo Puoti et al.
Massimo Iavarone et al.
Background and aims: Conflicting data on hepatocellular carcinoma (HCC) survival in people with HIV (PWH) may depend on tumour aggressiveness and access to curative treatments. We compared outcomes of two HCC cohorts acco...
Elevated Serum Bile Acids Predict Poor Liver Outcomes in Children With Alagille Syndrome: Results From the GALA Study Group [0.03%]
高血清胆酸可预测Alagille综合征儿童不良肝脏预后：来自GALA研究小组的结果
Carla Fiorella Murillo Perez,Shannon M Vandriel,Emmanuel M Gonzales et al.
Carla Fiorella Murillo Perez et al.
Background and aim: Alagille syndrome (ALGS) is a rare disorder characterised by cholestasis and extrahepatic manifestations. Given the current era of ileal bile acid transporter (IBAT) inhibitor therapies that reduce ser...
Bridging Association to Action: Reframing Environmental Exposure Assessment in PCE-Linked Liver Fibrosis [0.03%]
从关联到行动的桥梁：重新思考四氯乙烯相关肝纤维化的环境暴露评估
Man Sun,Dan Zang,Jun Chen
Man Sun
Endocrine Dysfunction in Cirrhosis: From Testosterone to Adrenal Precursors, Bridging Frailty and Prognosis [0.03%]
肝硬化的内分泌功能障碍：从睾丸激素到肾上腺前体，连接脆弱性和预后
Melinda Wang,Elliot B Tapper,Jennifer C Lai et al.
Melinda Wang et al.