Inequity in end-of-life care for patients with chronic liver disease in England [0.03%]
英国慢性肝病患者临终关怀的不平等现象
Hazel Woodland,Ryan M Buchanan,Andy Pring et al.
Hazel Woodland et al.
Background and aims: The World Health Assembly recommends integration of palliative care into treatment of patients with any life-limiting condition, yet patients with non-malignant disease are less likely to receive spec...
Combined use of the ELF test and CLivD score improves prediction of liver-related outcomes in the general population [0.03%]
联合使用ELF试验和CLivD评分可改善一般人群中肝病结局的预测能力
Fredrik Åberg,Kustaa Saarinen,Antti Jula et al.
Fredrik Åberg et al.
Background and aims: Effective and feasible population screening strategies are needed for the early detection of individuals at high risk of future severe liver-related outcomes. We evaluated the predictive performance o...
Risk of infections in non-alcoholic fatty liver disease: A nationwide population-based cohort study [0.03%]
非酒精性脂肪肝病感染风险全国队列研究
Ying Shang,Linnea Widman,Fahim Ebrahimi et al.
Ying Shang et al.
Background and aims: Previous literature suggests an association between non-alcoholic fatty liver disease (NAFLD) and infections. We aimed to determine the rate and risk of severe infections in NAFLD compared to the gene...
The greater impact of PNPLA3 polymorphism on liver-related events in Japanese non-alcoholic fatty liver disease patients: A multicentre cohort study [0.03%]
PNPLA3多态性对日本非酒精性脂肪肝病患者肝脏相关事件影响的队列研究
Yuya Seko,Kanji Yamaguchi,Toshihide Shima et al.
Yuya Seko et al.
Background & aims: PNPLA3 rs738409 has been associated with an increased risk of liver-related events in patients with non-alcoholic fatty liver disease (NAFLD). In this study, we investigated the epidemiology of NAFLD an...
Outcomes of accidental pregnancy during chronic hepatitis C treatment with direct-acting antiviral agents [0.03%]
直接抗病毒药物治疗慢性丙型肝炎期间意外怀孕的结局
Mohamed El-Kassas,Eslam Youssif,Ahmed Madkour et al.
Mohamed El-Kassas et al.
Hepatic recompensation according to Baveno VII criteria is linked to a significant survival benefit in decompensated alcohol-related cirrhosis [0.03%]
Baveno VII标准下的肝再代偿与酒精性失代偿期肝硬化的显著生存益处有关
Benedikt Silvester Hofer,Benedikt Simbrunner,Lukas Hartl et al.
Benedikt Silvester Hofer et al.
Background & aims: Removing the primary aetiological factor in decompensated cirrhosis may lead to a restoration of hepatic function. In this study, we investigated the clinical implications of recompensation and the subs...
Norman B Javitt
Norman B Javitt
Lack of endothelial autophagy does not impair liver regeneration after partial hepatectomy in mice [0.03%]
小鼠部分肝切除术后内皮自噬缺乏不影响肝脏再生
Genís Campreciós,Aina Anton,Anna Oncins et al.
Genís Campreciós et al.
Liver sinusoidal endothelial cells (LSEC) are key elements in regulating the liver response to injury and regeneration. While endothelial autophagy is essential to protect endothelial cells from injury-induced oxidative stress and fibrosis,...
Sweating it out: How physical activity can combat high genetic risk for nonalcoholic fatty liver disease [0.03%]
挥汗如雨：身体活动如何对抗非酒精性脂肪肝的高遗传风险
Jonathan G Stine,Stefano Romeo
Jonathan G Stine
Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer: An early exploratory analysis of real-world data [0.03%]
德瓦鲁单抗联合吉西他滨和顺铂治疗晚期胆道癌：真实世界数据分析的初步探索结果
Margherita Rimini,Lorenzo Fornaro,Sara Lonardi et al.
Margherita Rimini et al.
Background: The TOPAZ-1 phase III trial reported a survival benefit with the anti-programmed death cell ligand 1 (anti-PD-L1) durvalumab in combination with gemcitabine and cisplatin in patients with advanced biliary trac...