The crucial role of bioimage analysts in scientific research and publication [0.03%]
生物影像分析师在科学研究和出版物中的关键作用
Beth A Cimini,Peter Bankhead,Rocco D&#x;Antuono et al.
Beth A Cimini et al.
Bioimage analysis (BIA), a crucial discipline in biological research, overcomes the limitations of subjective analysis in microscopy through the creation and application of quantitative and reproducible methods. The establishment of dedicat...
Back to the future - 20 years of progress and developments in photonic microscopy and biological imaging [0.03%]
展望未来-光子显微镜和生物影像学二十年的研究进展与发展历程
Marie Erard,Cyril Favard,Luke D Lavis et al.
Marie Erard et al.
In 2023, the ImaBio consortium (imabio-cnrs.fr), an interdisciplinary life microscopy research group at the Centre National de la Recherche Scientifique, celebrated its 20th anniversary. ImaBio contributes to the biological imaging communit...
Inês Cunha,Emma Latron,Sebastian Bauer et al.
Inês Cunha et al.
Machine learning (ML) is transforming the field of image processing and analysis, from automation of laborious tasks to open-ended exploration of visual patterns. This has striking implications for image-driven life science research, partic...
Activation of the mitochondrial unfolded protein response regulates the dynamic formation of stress granules [0.03%]
线粒体未折叠蛋白反应的激活调节应激颗粒的动态形成
Marta Lopez-Nieto,Zhaozhi Sun,Emily Relton et al.
Marta Lopez-Nieto et al.
To rapidly adapt to harmful changes to their environment, cells activate the integrated stress response (ISR). This results in an adaptive transcriptional and translational rewiring, and the formation of biomolecular condensates named stres...
The dual Ras-association domains of Drosophila Canoe have differential roles in linking cell junctions to the cytoskeleton during morphogenesis [0.03%]
果蝇Canoe的双Ras结合结构域在形态建成期间将细胞连接与细胞骨架相连的过程中发挥不同的作用
Emily D McParland,Noah J Gurley,Leah R Wolfsberg et al.
Emily D McParland et al.
During development cells must change shape and move without disrupting dynamic tissue architecture. This requires robust linkage of cell-cell adherens junctions to the force-generating actomyosin cytoskeleton. Drosophila Canoe and mammalian...
Chemomechanical regulation of EZH2 localization controls epithelial-mesenchymal transition [0.03%]
表观遗传与机械力相互调控作用于上皮间质转化过程中的作用机制研究
Jessica L Sacco,Zachary T Vaneman,Ava Self et al.
Jessica L Sacco et al.
The methyltransferase enhancer of zeste homolog 2 (EZH2) regulates gene expression, and aberrant EZH2 expression and signaling can drive fibrosis and cancer. However, it is not clear how chemical and mechanical signals are integrated to reg...
Maria Clara Zanellati,Chih-Hsuan Hsu,Sarah Cohen
Maria Clara Zanellati
Eukaryotic cells are compartmentalized into membrane-bound organelles that must coordinate their responses to stimuli. One way that organelles communicate is via membrane contact sites (MCSs), sites of close apposition between organelles us...
Virginie Uhlmann,Matthew Hartley,Josh Moore et al.
Virginie Uhlmann et al.
The increasing technical complexity of all aspects involving bioimages, ranging from their acquisition to their analysis, has led to a diversification in the expertise of scientists engaged at the different stages of the discovery process. ...
Synchrotron X-ray imaging of soft biological tissues - principles, applications and future prospects [0.03%]
同步加速器X射线成像在软组织中的应用及发展前景
Jonas Albers,Angelika Svetlove,Elizabeth Duke
Jonas Albers
Synchrotron-based tomographic phase-contrast X-ray imaging (SRµCT or SRnCT) is a versatile isotropic three-dimensional imaging technique that can be used to study biological samples spanning from single cells to human-sized specimens. SRµ...
I am not a microscopist [0.03%]
我并不是一名显微镜专家
Seema Grewal,Helen L Zenner
Seema Grewal