Correction: Complexity and self-organization in the evolution of cell polarization [0.03%]
关于细胞极化演化的复杂性和自组织的更正论文
Marieke M Glazenburg,Liedewij Laan
Marieke M Glazenburg
Published Erratum
Journal of cell science. 2024 Dec 1;137(23):jcs263699. DOI:10.1242/jcs.263699 2024
Sara K Tucker,Douglas M McLaurin,Michael D Hebert
Sara K Tucker
Cajal bodies (CBs) are membraneless organelles whose mechanism of formation is still not fully understood. Many proteins contribute to the formation of CBs, including Nopp140 (NOLC1), WRAP53 and coilin. Coilin is modified on multiple differ...
Altered calcium responses and antioxidant properties in Friedreich's ataxia-like cerebellar astrocytes [0.03%]
类Friedreich共济失调小脑星形胶质细胞的钙反应和抗氧化特性异常
Chiara Marullo,Laura Croci,Iris Giupponi et al.
Chiara Marullo et al.
Friedreich's ataxia (FRDA) is a neurodegenerative disorder characterized by severe neurological signs, affecting the peripheral and central nervous system, caused by reduced frataxin protein (FXN) levels. While several studies highlight cel...
Dennis K Jeppesen,Qin Zhang,Robert J Coffey
Dennis K Jeppesen
Cells can communicate with neighboring and more distant cells by secretion of extracellular vesicles (EVs). EVs are lipid bilayer membrane-bound structures that can be packaged with proteins, nucleic acids and lipids that mediate cell-cell ...
Stem cell expressed CXCR4 regulates tissue composition in the vomeronasal organ [0.03%]
鼻腔感觉器官中的干细胞表达的CXCR4调控组织组成
André Dietz,Katja Senf,Eva M Neuhaus
André Dietz
The vomeronasal organ (VNO) detects signaling molecules that often prompt innate behaviors such as aggression and reproduction. Vomeronasal sensory neurons, classified into apical and basal lineages based on receptor expression, have a limi...
The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations [0.03%]
具有错义突变的细胞质蛋白被蛋白酶体降解时，DNAJA2同伴蛋白起到缓冲作用
Heather A Baker,Jonathan P Bernardini,Veronika Csizmók et al.
Heather A Baker et al.
Mutations can disrupt a protein's native function by causing misfolding, which is generally handled by an intricate protein quality control network. To better understand the triaging mechanisms of misfolded cytosolic proteins, we screened a...
The Ras-related nuclear GTPase RAN1 ensures pollen size and tube growth by maintaining the actin cytoskeleton [0.03%]
Ras相关的核GTP酶RAN1通过维持肌动蛋白细胞骨架保证花粉大小和萌发管生长
Yihao Li,Yuwan Zhao,Haining Zhang et al.
Yihao Li et al.
Controlling organ size in plants is a complex biological process influenced by various factors, including gene expression, genome ploidy and environmental conditions. Despite its importance for plant growth and development, the mechanisms u...
PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation [0.03%]
PIKFYVE抑制通过氨积累诱导内体和溶酶体来源的囊泡增大
Junsuke Uwada,Hitomi Nakazawa,Takeshi Kiyoi et al.
Junsuke Uwada et al.
FYVE-type zinc finger-containing phosphoinositide kinase (PIKFYVE), that is essential for PtdIns(3,5)P2 production, is an important regulator of lysosomal homeostasis. PIKFYVE dysfunction leads to cytoplasmic vacuolization; however, the und...
Suzan Kors,Anne-Lore Schlaitz
Suzan Kors
The endoplasmic reticulum (ER) is a dynamic and continuous membrane network with roles in many cellular processes. The importance and maintenance of ER structure and function have been extensively studied in interphase cells, yet recent fin...
Phosphorylation on serine 72 modulates Rab7A palmitoylation and retromer recruitment [0.03%]
丝氨酸72磷酸化调控Rab7A棕榈酰化及retromer募集
Graziana Modica,Laura Tejeda-Valencia,Etienne Sauvageau et al.
Graziana Modica et al.
Rab7A has a key role in regulating membrane trafficking at late endosomes. By interacting with several different effectors, this small GTPase controls late endosome mobility, orchestrates fusion events between late endosomes and lysosomes, ...