Drosophila Clu ribonucleoprotein particle dynamics rely on the availability of functional Clu and translating ribosomes [0.03%]
Clu核糖核蛋白颗粒的动力学取决于功能性Clu和翻译性核糖体的存在
Hye Jin Hwang,Kelsey M Sheard,Rachel T Cox
Hye Jin Hwang
Drosophila Clu is a conserved multi-domain ribonucleoprotein essential for mitochondrial function that forms dynamic particles within the cytoplasm. Unlike stress granules and Processing bodies, Clu particles disassemble under nutritional o...
Annette Müller-Taubenberger,Ludwig Eichinger
Annette Müller-Taubenberger
Aline Grata,Romain Levayer
Aline Grata
The robustness and plasticity of epithelial tissues rely on the capacity of such tissues to eliminate cells without affecting their sealing. This is achieved by epithelial cell extrusion - a well-orchestrated series of remodelling steps inv...
Cell-end marker proteins are required for hyphal ring formation and size determination of traps in Arthrobotrys flagrans [0.03%]
细胞末端标记蛋白是Arthrobotrys flagrans菌丝环形成和圈套大小决定所必需的
Marius Kriegler,Valentin Wernet,Birgit Hetzer et al.
Marius Kriegler et al.
Filamentous fungi grow by apical extension where secretory vesicles are transported long distances by microtubules and by actin prior to fusion with the cell membrane. Apical, membrane-bound cell-end marker proteins (CEMPs) organise the cyt...
Intra-Golgi Golgin PpSgm1 and GRIP domain Golgin PpImh1 synergistically mediate Golgi cisternal stacking [0.03%]
内质网介稳小泡的形成机制及在植物生长发育中的作用研究杂交水稻育种中理想株型基因的克隆与功能分析高尔基体顺面膜囊 stacks 形成的分子机制
Roma Dahara,Dibyendu Bhattacharyya
Roma Dahara
Regulation of the distinctive stacked Golgi morphology remains an unresolved subject. Using budding yeast Pichia pastoris, we previously documented the role of GRIP domain Golgin PpImh1 in cisternal stacking, regulated by the Arl3-Arl1 GTPa...
Enhancement of CEP215/CDK5RAP2 dynamics for spindle pole assembly during mitosis [0.03%]
有丝分裂期间CEP215/CDK5RAP2动态增强以促进纺锤杆组装
Hyunjeong Yoo,Taehyun Kim,Sungjin Ryu et al.
Hyunjeong Yoo et al.
The microtubule organizing activity of centrosomes fluctuates during the cell cycle, reaching the highest levels at M phase. CEP215/CDK5RAP2 is a key pericentriolar material (PCM) protein for microtubule organization of the human centrosome...
Pyruvate plus uridine augment mitochondrial respiration and prevent cardiac hypertrophy in zebrafish and H9c2 cells [0.03%]
丙酮酸和尿苷增强斑马鱼和H9c2细胞线粒体呼吸并防止心脏肥大
Soumyajit Mukherjee,Shreya Das,Surajit Das et al.
Soumyajit Mukherjee et al.
Dysfunction of mitochondrial pyruvate oxidation and aberrant respiratory chain components are common in cardiac defects. However, the precise role of mitochondrial respiration in cardiomyocyte hypertrophy is unclear. Phenylephrine (PE) trea...
Kailash Venkatraman,Nicolas-Frédéric Lipp,Itay Budin
Kailash Venkatraman
Unique membrane architectures and lipid building blocks underlie the metabolic and non-metabolic functions of mitochondria. During eukaryogenesis, mitochondria likely arose from an alphaproteobacterial symbiont of an Asgard archaea-related ...
Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain [0.03%]
纳米抗体揭示了N端卷曲螺旋结构域的结构灵活性和调节作用力
Ya Gao,Vikas A Tillu,Yeping Wu et al.
Ya Gao et al.
Caveolae are abundant plasma membrane structures that regulate signalling, membrane homeostasis, and mechanoprotection. Their formation is driven by caveolins and cavins and their coordinated interactions with lipids. We have developed nano...
EdU tracking of leukocyte recruitment in mouse models of ischemic stroke and sterile lung inflammation [0.03%]
用于缺血性脑卒中和非感染性肺部炎症小鼠模型的白细胞招募的EdU追踪方法
Erika Arias,Maureen E Haynes,Neil A Nadkarni et al.
Erika Arias et al.
The discovery of copper(I)-catalyzed azide-alkyne cycloaddition (click chemistry) has significantly advanced the detection of proliferating cells by utilizing 5-ethynyl-2'-deoxyuridine (EdU). EdU, a thymidine analogue, is incorporated into ...