Jonathan Slack is Emeritus Professor at the University of Bath. His research interests have included early development of the Xenopus embryo, regeneration of limbs and tails, and attempts to reprogramme other cell types to β cells. In Sept...
Fei Sun,Kenneth D Poss
Fei Sun
Tissue regeneration is not simply a local repair event occurring in isolation from the distant, uninjured parts of the body. Rather, evidence indicates that regeneration is a whole-animal process involving coordinated interactions between d...
Syncytia are multinucleated cells that form distinct functional compartments. In a new paper in Development, Charles Ettensohn and colleagues use the sea urchin embryonic skeleton to study how specialized compartments are generated in a syn...
Caenorhabditis elegans germ granules are present in distinct configurations and assemble in a hierarchical manner [0.03%]
模式生物线虫 Caenorhabditis elegans 的生殖细胞颗粒以不同的方式存在并层次化地组装在一起
Celja J Uebel,Sanjana Rajeev,Carolyn M Phillips
Celja J Uebel
RNA silencing pathways are complex, highly conserved, and perform crucial regulatory roles. In Caenorhabditis elegans germlines, RNA surveillance occurs through a series of perinuclear germ granule compartments - P granules, Z granules, SIM...
Yolanda Moyano Rodriguez,Maud Borensztein
Yolanda Moyano Rodriguez
The last edition of the X-chromosome inactivation (XCI) meeting was held as an EMBO workshop in Berlin on 19-22 June 2023. The conference took place at the Harnack-haus in the Dahlem district, birthplace of the first modern research campus,...
FRL and DAAM are required for lateral adhesion of interommatidial cells and patterning of the retinal floor [0.03%]
FRL和DAAM是间视盘细胞侧向黏附及视网膜基部图案化所必需的
Gabriella Gazsó-Gerhát,Rita Gombos,Krisztina Tóth et al.
Gabriella Gazsó-Gerhát et al.
Optical insulation of the unit eyes (ommatidia) is an important prerequisite of precise sight with compound eyes. Separation of the ommatidia is ensured by pigment cells that organize into a hexagonal lattice in the Drosophila eye, forming ...
ABA guides stomatal proliferation and patterning through the EPF-SPCH signaling pathway in Arabidopsis thaliana [0.03%]
在拟南芥中，ABA通过EPF-SPCH信号途径指导气孔的增殖和排列
Deka Mohamed,Eliana Vonapartis,Dennedy Yrvin Corcega et al.
Deka Mohamed et al.
Adaptation to dehydration stress requires plants to coordinate environmental and endogenous signals to inhibit stomatal proliferation and modulate their patterning. The stress hormone abscisic acid (ABA) induces stomatal closure and restric...
ARRDC5 deficiency impairs spermatogenesis by affecting SUN5 and NDC1 [0.03%]
ARRDC5缺陷通过影响SUN5和NDC1损害精子发生
Ruyi Liu,Ronggui Qu,Qun Li et al.
Ruyi Liu et al.
Sperm with normal morphology and motility are essential for successful fertilization, and the strong attachment of the sperm head-tail coupling apparatus to the nuclear envelope during spermatogenesis is required to ensure the integrity of ...
Toll-like receptor signalling via IRAK4 affects epithelial integrity and tightness through regulation of junctional tension [0.03%]
TLR信号通过IRAK4影响上皮完整性和紧密性及其连接张力的调节作用
Jesse Peterson,Kinga Balogh Sivars,Ambra Bianco et al.
Jesse Peterson et al.
Toll-like receptors (TLRs) in mammalian systems are well known for their role in innate immunity. In addition, TLRs also fulfil crucial functions outside immunity, including the dorsoventral patterning function of the original Toll receptor...
In toto imaging of glial JNK signaling during larval zebrafish spinal cord regeneration [0.03%]
脊髓受损后脊椎鱼幼虫少突胶质细胞JNK信号通路的整体成像
Clayton J Becker,Valentina Cigliola,Pierre Gillotay et al.
Clayton J Becker et al.
Identification of signaling events that contribute to innate spinal cord regeneration in zebrafish can uncover new targets for modulating injury responses of the mammalian central nervous system. Using a chemical screen, we identify JNK sig...